Phillips, Robert - The University of Georgia

研究领域

Analytical Chemistry/Inorganic Chemistry/Organic Chemistry/Physical Chemistry/Biological Chemistry/Chemical Education/Computational/Theoretical Chemistry/Environmental/Atmospheric Chemistry/Materials Chemistry and Nanoscience

近期论文

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Kumar, S. ; Gawandi, V. B. ; Capito, N. ; Phillips, R. S. Substituent effects on the reaction of beta-benzoylalanines with Pseudomonas fluorescens kynureninase. Biochemistry 2010, 49, 7913-9. Phillips, R. S. ; Lima, S. ; Khristoforov, R. ; Sudararaju, B. Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics. Biochemistry 2010, 49, 5066-73. Marchal, S. ; Font, J. ; Ribó, M. ; Vilanova, M. ; Phillips, R. S. ; Lange, R. ; Torrent, J. Asymmetric kinetics of protein structural changes. Accounts of chemical research 2009, 42, 778-87. Lima, S. ; Kumar, S. ; Gawandi, V. ; Momany, C. ; Phillips, R. S. Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity. Journal of medicinal chemistry 2009, 52, 389-96. Lima, S. ; Sundararaju, B. ; Huang, C. ; Khristoforov, R. ; Momany, C. ; Phillips, R. S. The crystal structure of the Pseudomonas dacunhae aspartate-beta-decarboxylase dodecamer reveals an unknown oligomeric assembly for a pyridoxal-5'-phosphate-dependent enzyme. Journal of molecular biology 2009, 388, 98-108. Phillips, R. S. ; Miles, E. W. ; McPhie, P. ; Marchal, S. ; Georges, C. ; Dupont, Y. ; Lange, R. Pressure and temperature jump relaxation kinetics of the conformational change in Salmonella typhimurium tryptophan synthase L-serine complex: large activation compressibility and heat capacity changes demonstrate the contribution of solvation. Journal of the American Chemical Society 2008, 130, 13580-8. Osborne, A. S. ; Som, P. ; Metcalf, J. L. ; Phillips, R. S. Regioselective nitration of N(alpha),N(1)-bis(trifluoroacetyl)-L-tryptophan methyl ester: efficient synthesis of 2-nitro and 6-nitro-N-trifluoroacetyl-L-tryptophan methyl ester. Bioorganic & medicinal chemistry letters 2008, 18, 5750-2. Musa, M. M. ; Ziegelmann-Fjeld, K. I. ; Vieille, C. ; Phillips, R. S. Activity and selectivity of W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus in organic solvents and ionic liquids: mono- and biphasic media. Organic & biomolecular chemistry 2008, 6, 887-92. Song, L. ; Teng, Q. ; Phillips, R. S. ; Brewer, J. M. ; Summers, A. O. 19F-NMR reveals metal and operator-induced allostery in MerR. Journal of molecular biology 2007, 371, 79-92. Musa, M. M. ; Ziegelmann-Fjeld, K. I. ; Vieille, C. ; Zeikus, G. J. ; Phillips, R. S. Xerogel-encapsulated W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus performs asymmetric reduction of hydrophobic ketones in organic solvents. Angewandte Chemie (International ed. in English) 2007, 46, 3091-4.