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Dr. Knopf's teaching responsibilities and expertise are in the general field of product design & advanced manufacturing. His areas of research interest includeengineering design, 3D shape reconstruction, laser microfabrication, micro-optics andbioelectronic imaging arrays. Past contributions have been to the development of intelligent systems for engineering design including studies on the characterization of micro geometry flaws in product data exchange, efficient packing of 3D parts for layered manufacturing, and the adaptive reconstruction of complex freeform surfaces. The innovative surface modeling algorithms have been applied to the reconstruction of complex bone geometry and fragmented archaeological artifacts. Other contributions include self-organizing feature maps that convert large numeric data sets into geometric forms for interactive data exploration and visualization. In recent years, the focus of research has significantly expanded in the areas of laser microfabrication, micro-optics and light driven technologies. These technologies include a unique approach to surface geometry measurement using an unconstrained range-sensor head [US patent 6,542,249], micro-optic element design for large area light guides and curtains, non-lithographic fabrication of metallic micro-mold masters by laser machining and welding, laser micro polishing and development of several bioelectronic devices that exploit the photoelectric signals generated by dried bacteriorhodopsin (bR) films. Biologically-based light activated transducers represent a new sensor technology that can be fabricated on flexible polymer substrates for creating novel imaging and biosensor systems [USA Patent No. 7,573,024]. Current research involves the development of electrically conductive graphene-based inks and novel fabrication processes for printing electronic circuitry on a variety of mechanically flexible surfaces(e.g. polymers, paper, and biocompatible silk). In addition, he has co-edited two CRC Press volumes entitled Smart Biosensor Technology and Optical Nano and Micro Actuator Technology. Professor Knopf has acted as a technical reviewer for numerous academic journals, conferences, and granting agencies and has co-chaired several international conferences.

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Wang, W.W., Knopf, G.K. and Bassi, A.S. (2009) "Bioelectronic photodetector and imaging arrays based on bacteriorhodopsin (bR) thin films and flexible printed electronic circuits" [USA Patent No. 7,573,024 - issued August 2009 ]. Kofman, J. and Knopf, G.K. (2003) "Method and apparatus for three-dimensional shape measurement with unconstrained object and sensor motion" [USA Patent No. 6,542,249 - issued April 2003; Canadian Patent CA 2278108 - issued January 2008]. Kaneko, S., Cho, H-S., Knopf, G.K. and Tutsch, R. (Eds.) (2004), Machine Vision and its Optomechatronic Applications. SPIE vol. 5603, Bellingham WA: SPIE Press [ISSN: 0277-786X]. Knopf, G.K. (Ed.) (2003), Optomechatronic Systems IV. SPIE vol. 5264, Bellingham WA: SPIE Press [ISBN: 0-8194-5152-5]. Cho, H.-S. and Knopf, G.K. (Eds.) (2000), Optomechatronic Systems. SPIE vol. 4190, Bellingham WA: SPIE Press [ISBN: 0-8194-3855-3]. Knopf, G.K. and Orban, P. (Eds.) (2000), Sensors and Controls for Intelligent Manufacturing. SPIE vol. 4191, Bellingham WA: SPIE Press [ISBN: 0-8194-3856-1]. Knopf, G.K., Muir, P. and Orban, P. (Eds.) (1999), Sensors and Controls for Intelligent Machining and Manufacturing Mechatronics. SPIE vol. 3832, Bellingham WA: SPIE Press [ISBN: 0-8194-3425-6]. Knopf, G.K. (2013), “Light driven and optically actuated technologies”, in Optical Nano and Micro Actuator Technology, G.K. Knopf and Y. Otani (Eds.), CRC Press, pp. 3 – 46. Knopf, G.K. and Al-Aribe, K.M. (2013), “Light driven micro and nanofluidics”, in Optical Nano and Micro Actuator Technology, G.K. Knopf and Y. Otani (Eds.), CRC Press, pp. 375 – 404. Knopf, G.K. and Otani ,Y. (2013), “Perspectives on light driven actuators”, in Optical Nano and Micro Actuator Technology, G.K. Knopf and Y. Otani (Eds.), CRC Press, pp. 597 – 603. Knopf, G.K. and Wang, W.W. (2010) “Biophotoreceptor arrays”, Encyclopedia of Industrial Biotechnology, M.C. Flickinger and C. Vona (Eds.), John Wiley [available online; ~ 30 pages]. Knopf, G.K. (2007), “Smart biosensor functions – a machine learning perspective”, in Smart Biosensor Technology, G.K. Knopf and A.S. Bassi (Eds.), CRC Press, pp. 151 – 176. Wang, W.W., Knopf, G.K. and Bassi, A.S. (2007), “Protein-based photoreceptor array and flexible plastic substrates”, in Smart Biosensor Technology, G.K. Knopf and A.S. Bassi (Eds.), CRC Press, pp. 461 – 504. Bassi, A.S. and Knopf, G.K. (2007), “Perspectives on biosensor technology”, in Smart Biosensor Technology, G.K. Knopf and A.S. Bassi (Eds.), CRC Press, pp. 617 – 630. Barari, A., ElMaraghy, H.A. and Knopf, G.K. (2007), “Evaluation of geometric deviations in sculptured surfaces using probability density estimation”, in Models for Computer Aided Tolerancing in Design and Manufacturing, J. K. Davidson (Ed.), Springer Netherlands, pp. 135-146. Knopf, G.K. and Johnson, J.A. (2006), “Computer aided design”, in Wiley Encyclopedia of Biomedical Engineering, Metin Akay (Ed.), John Wiley [13 pages – electronic access through Wiley]. Knopf G.K. and Sangole, A. (2006), “Data visualization”, in Wiley Encyclopedia of Biomedical Engineering, Metin Akay (Ed.), John Wiley [13 pages – electronic access through Wiley]. Knopf, G.K. (2006), “Optical actuation and control”, in Handbook of Optoelectronics, J. Dakin and R.W. Brown (Eds.), CRC Press, pp. 1453-1479. Knopf, G.K. (2003), “Design of optomechatronic products and processes”, in Opto-Mechatronic Systems: Techniques and Applications Handbook, H.S. Cho (Ed.), CRC Press, pp. 2.1-2.27. Knopf, G.K. and Bassi, A.S. (2003), “Biological-based optical sensors and transducers”, in Opto-Mechatronic Systems: Techniques and Applic. Handbook, H.S. Cho (Ed.), CRC Press, pp. 6.1–6.22. Gupta, M.M. and Knopf, G.K. (1994), “Neuro-vision systems: a tutorial”, in Neuro-Vision Systems: Principles and Applications, M.M. Gupta and G.K. Knopf (Eds.), New York: IEEE Press, pp. 1 - 34. Gupta, M.M. and Knopf, G.K. (1992), “Fuzzy neural network approach to control systems”, in Analysis and Management of Uncertainty: Theory and Application, B.M. Ayyub, M.M. Gupta and L.N. Kanal (Eds.), North Holland, New York, pp. 183 - 197. Gupta, M.M., Knopf, G.K. and Nikiforuk, P.N. (1988), “Edge perception using fuzzy logic”, in Fuzzy Computing, North-Holland, M.M. Gupta and T. Yamakawa (Eds.), Amsterdam, pp. 35 - 51. Gupta, M.M., Knopf, G.K. and Nikiforuk, P.N. (1988), “Sinusoidal-based cognitive mapping functions”, in Fuzzy Logic in Knowledge-based Systems, M.M. Gupta and T. Yamakawa (Eds.), North-Holland, Amsterdam, pp. 69 - 92.

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