Marsden, Mungo - University of Waterloo

个人简介

Mungo Marsden investigates the molecular mechanisms that mediate changes in biological form, in particular the modulation of cell adhesion states. Regulation of cell adhesion is not only important during early cell development, but is also fundamental to a wide variety of health related issues, such as cancer and wound healing. Physiology, Cell and Developmental Biology Molecular Genetics Journal Reviews PLOS One BMC Developmental Biology Development Developmental Biology 1995 PhD Developmental Biology, University of Victoria 1989 MSc Cell and Molecular Biology, University of Calgary 1987 BSc University of Calgary

研究领域

Professor Marsden's research interests are centered around the molecular mechanisms that mediate changes in biological form. In particular he is interested in the modulation of cell adhesion states that allow for the complex three dimensional rearrangements that characterize early embryogenesis. These changes in adhesive state are under strict spatial and temporal control, and in many cases stem from extra-cellular signals that cells perceive in their immediate environment. Professor Marsden's major line of research involve two families of cell adhesion molecules, the integrins, and the cadherins. Recent evidence indicates the regulation of adhesive states is through a direct cross-talk between these molecules, indicating a coordination between cell–matrix and cell–cell adhesion. This regulation of cell adhesion is not only found during early development but is also of fundamental significance to a wide variety of health related issues such as cancer and wound healing.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

2015 Kostadinka Bizheva, Bingyao Tan, Tyler Monahan, Julia Zangalous, Mungo Marsden, Mojtaba Hajialamdari 2 µm axial resolution, fiber-optic SD-OCT operating at 1300 nm for cellular resolution imaging of biological tissue. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine 2015 M. Sheikholeslam, S. Wheeler, K. Duke, M. Marsden, M. Pritzker and P. Chen. Peptide and Peptide-Carbon Nanotube Hydrogels as Scaffolds for Tissue & 3D Tumor Engineering. Nanoscale (accepted) 2012 A.Taeb, , M. A. Basha, S. Gigoyan, M. Marsden, S. Safavi-Naeini Label-Free DNA Sensing Using Millimeter-Wave Silicon WGM Resonator Transactions on Microwave Theory and Techniques 2012 Dinushan Nesan, Maryam Kamkar, Jeffery Burrows, Ian C. Scott, Mungo Marsden and Mathilakath M. Vijayan Glucocorticoid recepter signalling is critical for early development in zebrafish . Endocrinology 153(3): 1288-1300. 2010 GW Brodland, X Chen, P Lee, M Marsden From Genes to Neural Tube Defects (NTDs): Insights from Multi-scale Computational Modeling HFSP JOURNAL 4 (3) Pages: 142-152