Gabryelski, Wojciech - University of Guelph

个人简介

B.Sc. (1986) - Gdansk Institute of Technology (Gdansk, Poland) Chemistry and Chemical Engineering M.Sc. (1986) - Gdansk Institute of Technology (Gdansk, Poland) Analytical Chemistry Ph.D. (2000) - University of Alberta (Edmonton, Alberta) Mass Spectrometry Appointed to faculty of the University of Guelph Department of Chemistry in August 2004. Currently a member of the American Society of Mass Spectrometry

研究领域

Our research in the area of analytical mass spectrometry focuses on the development and application of new, effective, and convenient techniques for characterization of chemical components of complex mixtures typically found in environmental and biological samples. Our strategy for improving the existing analytical methods is coupling mass spectrometry with nano-flow Ultra-high Performance Liquid Chromatography (UPLC) (pictured here) and High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS).

近期论文

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22. Beach, D. G., Gabryelski, W. “Revisiting the Reactivity Uracil During Collision Induced Dissociation: Tautomerism and Charge Directed Processes.” J. Am. Soc. Mass Spectrom. 2012, 23, 858-868. 21. Witham, A. A., Beach, D. G., Gabryelski, W., Manderville, R. A. “Hydroxyl Radical-Induced Oxidation of a Phenolic C-Linked-2’-Deoxyguanosine Adduct Yields a Reactive Catechol” Chem. Res. Toxicol. 2012, 25, 315-325. 20. Beach, D. G., Gabryelski, W. „Non-Target Analysis of Urine by Electrospray Ionization – High Field Asymmetric Waveform Ion Mobility – Tandem Mass Spectrometry (ESI-FAIMS-MS/MS).” Anal. Chem. 2011, 83, 9170-9113. 19. Sagoo, S., Beach, D. G., Manderville, R. A., Gabryelski, W. “Tautomerization in Gas Phase Ion Chemistry of Isomeric C-8 Deoxyguanosine Adducts From Phenol-Induced DNA Damage.” J. Mass Spectrom. 2011, 46, 41-49. 18. Omumi, A., Beach, D. G., Baker, M., Gabryelski, W., Manderville, R. A. “Post-Synthetic Guanine Arylation of DNA by Suzuki-Miyaura Cross-Coupling.” J. Am. Chem. Soc. 2011, 133, 42-50. (Cover Article, January 12) 17. Kulikov, N., Baker, M., Gabryelski W. “Collision Induced Dissociation of Protonated N-Nitrosodimethylamine by Ion Trap Mass Spectrometry: Ultimate Carcinogens in Gas Phase” Int. J. Mass Spectrom. 2009, 288, 75-83. 16. Pfohl-Leszkowicz, A., Gabryelski, W., Manderville, R. A. “Formation of 2 '-deoxyguanosine-carbon 8-bound Ochratoxin A Adduct in Rat Kidney DNA” Mol. Nutr. Food Res. 2009, 53, 154-155. 15. Weishar, J. L., McLaughlin, C. K., Baker, M., Gabryelski, W., Manderville, R. A. “Oxidation of a Biomarker for Phenol Carcinogen Exposure: Expanding the Redox Chemistry of 2 '-Deoxyguanosine” Org. Lett. 2008, 1839-1842. 14. Baker, M., Gabryelski W. “Collision Induced Dissociation of Deprotonated Glycolic Acid” Int. J. Mass Spectrom. 2007, 262, 128-135. 13. Baker, M., Gabryelski, W. “Collision induced dissociation of deprotonated glycolic acid” Int. J. Mass Spectrom. 2007, 262, 128–135. 12. Sultan, J., Gabryelski, W. “Structural Identification of Highly Polar Non-target Contaminants in Drinking Water by ESI-FAIMS-Q-TOF-MS.” Anal. Chem. 2006; 78(9); 2905-2917, (Accelerated Article). 11. Gabryelski, W., Froese, K. L. “Characterization of Naphthenic Acids by Electrospray Ionization High-Field Asymmetric Waveform Ion Mobility Mass Spectrometry.” Anal . Chem. 2003, 75, 4612-4623. 10. Gabryelski, W., Froese, K. L. “Comparison of High-Field Asymmetric Waveform Ion Mobility Mass Spectrometry (FAIMS) with GC methods in analysis of haloacetic acids in drinking water” Anal. Chem. 2003, 75, 2478-2486. 9. Gabryelski, W., Froese, K. L. “Rapid and Sensitive Differentiation of Anomers, Linkage and Position Isomers of Disaccharides using High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS)” J. Am. Soc. Mass Spectrom. 2003, 14 (3), 265-277. 8. Wu, F., Gabryelski, W., Froese, K. L. “Improved gas chromatography methods for micro-volume analysis of haloacetic acids in water and biological matrices” Analyst, 2002,10, 1318-1323. 7. Gabryelski, W., Li, L. “Photoinduced Dissociation of Electrospray Generated Ions in an Ion Trap/Time-of-Flight Mass Spectrometer using a Pulsed CO2Laser.” Rapid Commun. Mass Spectrom., 2002, 16, 1805-1811. 6. Yalcin, T., Gabryelski, W., Li, L. “Structural Analysis of Polymer End Groups by Electrospray Ionization High-Energy Collision-Induced Dissociation Tandem Mass Spectrometry.” Anal. Chem., 2000, 72, 3847-3852. 5. Gabryelski, W., Li, L. “Photo-Induced Dissociation of Electrospray Generated Ions in an Ion Trap/Time-of-Flight Mass Spectrometer.” Rev. Sci. Instruments, 1999, 70, 4192-4199. 4. Gabryelski, W., Purves, R. W., Li, L. “Characterization of an ESI Ion Trap/Linear TOF Mass Spectrometer for PTH-Amino Acid Analysis.” Int. J. Mass Spectrom. Ion Processes, 1998, 176, 213-225. 3. Yalcin, T., Gabryelski, W., Li, L. “Dissociation of Protonated Phenylthiohydantoin-Amino Acids and Phenylthiocarbamoyl-Dipeptides.” J. Mass Spectrom.,1998, 33, 543-553. 2. Purves, R. W., Gabryelski, W., Li, L. “Investigation of the Quantitative Capabilities of an ESI Ion Trap/Linear TOF Mass Spectrometer.” Rapid Commun. Mass Spectrom., 1998, 12, 695-700. 1. Purves, R. W., Gabryelski, W., Li, L. “The Effect of Using Silicon Based Diffusion Pump Fluid on Spectral Quality in an ESI Ion Trap/TOF Mass Spectrometer.” Rev. Sci. Instrum. 1997, 68 (8), 3252-3253.