Kilkenny, Dawn M. - University of Toronto - Institute of Biomaterials & Biomedical Engineering

个人简介

Institute of Biomaterials & Biomedical Engineering

研究领域

Professor Kilkenny’s current research interest is in intracellular signalling and cellular interaction with the extracellular environment, particularly during migration. Her specific interests relate to fibroblast growth factors (FGFs) and signalling through FGF receptors.

近期论文

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Autofluorescence imaging of living pancreatic islets reveals fibroblast growth factor-21 (FGF21)-induced metabolism. Sun MY, Yoo E, Green BJ, Altamentova SM, Kilkenny DM, Rocheleau JV. Biophysical Journal. 2012 Dec 5. 103(11):2379-2388. Dynamics and Distribution of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex. Ming AY, Yoo E, Vorontsov EN, Altamentova SM, Kilkenny DM, Rocheleau JV. J Biol Chem. 2012 Jun 8. 287(24):19997-20006. Examining Pancreatic Islet Lipotoxicity by Two-photon NAD(P)H imaging in a Microfluidic Device. J Rocheleau, M Sun and D Kilkenn. Microscopy and Microanalysis. 2011 Oct. 17(2): 1226-1227. Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): Functional characterization and interindividual variability. Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB. Pharmacogenet Genomics. 2010 Jan. 20(1):45-57. Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity. Smith TK, Hager HA, Francis R, Kilkenny DM, Lo CW, Bader DM. Proc Natl Acad Sci U S A. 2008 Jun 17. 105(24):8298-303. CMF1-Rb interaction promotes myogenesis in avian skeletal myoblasts. Robertson JB, Zhu T, Nasreen S, Kilkenny D, Bader D, Dees E. Dev Dyn. 2008 May. 237(5):1424-33.