个人简介

Ph.D. Texas A&M University

研究领域

Animal Biology Bioinformatics & Computational Biology Biotechnology Comparative Genomics Evolutionary Biology Genetics Molecular Biology Plant Biology Synthetic Biology Systems Biology

Transposable elements (TEs) form a major community in eukaryotic genome ecosystems, where they often account for at least half of total content. The discovery of transposons has forced biologists to view genomes as much more dynamic systems than previously imagined. In addition, TE derived DNA tools are widely used in gene discovery and transgenesis. The most intriguing issues surrounding TEs are their interaction with host genome and their persistent proliferation during evolution despite being mutagens. Our research aims to understand how transposable elements shape genome function and evolution.

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Procedures for Mucosal Immunization and Analyses of Cellular Immune Response to Candidate HIV Vaccines in Murine and Nonhuman Primate Models.Singh S, Nehete P, Hanley P, Nehete B, Yang G, He H, Anthony SM, Schluns KS, Sastry KJ.Methods Mol. Biol. 2014;1184:417-55 pubmed Tc1-like transposable elements in plant genomes.Liu Y, Yang G.Mob DNA 2014;5:17 pubmed Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.Singh S, Yang G, Schluns KS, Anthony SM, Sastry KJ.PLoS ONE 2014;9(3):e90001 pubmed Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis).Nehete PN, Hanley PW, Nehete BP, Yang G, Ruiz JC, Williams L, Abee CR, Sastry KJ.PLoS ONE 2013;8(11):e79836 pubmed On a class of two-dimensional Douglas and projectively flat Finsler metrics.Yang G.ScientificWorldJournal 2013;2013:291491 pubmed Miniature inverted-repeat transposable elements: discovery, distribution, and activity.Fattash I, Rooke R, Wong A, Hui C, Luu T, Bhardwaj P, Yang G.Genome 2013 Sep;56(9):475-86 pubmed Birth of three stowaway-like MITE families via microhomology-mediated miniaturization of a Tc1/Mariner element in the yellow fever mosquito.Yang G, Fattash I, Lee CN, Liu K, Cavinder B.Genome Biol Evol 2013;5(10):1937-48 pubmed Draft genome sequence of the mulberry tree Morus notabilis.He N, Zhang C, Qi X, Zhao S, Tao Y, Yang G, Lee TH, Wang X, Cai Q, Li D, Lu M, Liao S, Luo G, He R, Tan X, Xu Y, Li T, Zhao A, Jia L, Fu Q, Zeng Q, Gao C, Ma B, Liang J, Wang X, Shang J, Song P, Wu H, Fan L, Wang Q, Shuai Q, Zhu J, Wei C, Zhu-Salzman K, Jin D, Wang J, Liu T, Yu M, Tang C, Wang Z, Dai F, Chen J, Liu Y, Zhao S, Lin T, Zhang S, Wang J, Wang J, Yang H, Yang G, Wang J, Paterson AH, Xia Q, Ji D, Xiang Z.Nat Commun 2013;4:2445 pubmed Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.Weaver EA, Nehete PN, Nehete BP, Yang G, Buchl SJ, Hanley PW, Palmer D, Montefiori DC, Ferrari G, Ng P, Sastry KJ, Barry MA.PLoS ONE 2013;8(7):e67574 pubmed MITE Digger, an efficient and accurate algorithm for genome wide discovery of miniature inverted repeat transposable elements.Yang G.BMC Bioinformatics 2013;14:186 pubmed A rice Stowaway MITE for gene transfer in yeast.Fattash I, Bhardwaj P, Hui C, Yang G.PLoS ONE 2013;8(5):e64135 pubmed HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex.Wang X, Singh S, Jung HY, Yang G, Jun S, Sastry KJ, Park JI.J. Biol. Chem. 2013 May;288(22):15474-80 pubmed