个人简介

Ph.D. Nagoya University 1994

研究领域

Biotechnology Chemical Biology Comparative Genomics Functional Genomics Genetics Metabolomics Molecular Biology Plant Biology Systems Biology

Plant hormones are low-abundant compounds, which elicit numerous biological processes essential for plant growth and development. Recent progress in functional genomics reveals that elucidation of hormone action mechanism is the key to engineer plants with enhanced performance as well as to evaluating the short- and long-term effects of genetic modifications in plants. My laboratory will study how hormone levels are regulated. In particular, we will focus on elucidating the molecular mechanisms by which regulate abscisic acid metabolism and movement.

近期论文

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NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis.Yan D, Easwaran V, Chau V, Okamoto M, Ierullo M, Kimura M, Endo A, Yano R, Pasha A, Gong Y, Bi YM, Provart N, Guttman D, Krapp A, Rothstein SJ, Nambara E. Nat. Commun. 2016 Oct 12;7:13179. doi: 10.1038/ncomms13179. pubmed CATchUP: A web database for spatiotemporally regulated genes.Nakamura Y, Kudo T, Terashima S, Saito M, Nambara E, Yano K. Plant Cell Physiol. 2016 doi: 10.1093/pcp/pcw199. pubmed Highly sprouting-tolerant wheat grain exhibits extreme dormancy and cold imbibition-resistant accumulation of abscisic acid. Kashiwakura Y, Kobayashi D, Jikumaru Y, Takebayashi Y, Nambara E, Seo M, Kamiya Y, Kushiro T, Kawakami N. Plant Cell Physiol. 2016. 57: 715-732. pubmed ANAC032 positively regulates age-dependent and stress-induced senescence in Arabidopsis thaliana.Mahmood K, El-Kereamy A, Kim SH, Nambara E, Rothstein SJ. Plant Cell Physiol. 2016. 57: 2029-2046. pubmed S-nitrosylation triggers ABI5 degradation to promote seed germination and post-germinative development.Albertos P, Romero-Puertas MC, Tatematsu K, Mateos I, Sanchez-Vicente I, Nambara E, Lorenzo O. Nat. Commun. 2015. 6: 8669. doi: 10.1038/ncomms9669. pubmed Overexpression of the CC-type glutaredoxin, OsGRX6 affects hormone and nitrogen status in rice plants.El-Kereamy A, Bi YM, Mahmood K, Ranathunge K, Yaish MW, Nambara E, Rothstein SJ. Front. Plant Sci. 2015. 6: 934. doi: 10.3389/fpls.2015.00934. eCollection 2015. pubmed Sustained low abscisic acid levels increase seedling vigor under cold stress in rice (Oryza sativa L.).Mega R, Meguro-Maoka A, Endo A, Shimosaka E, Murayama S, Nambara E, Seo M and Sato S. Sci. Rep. 2015. 5:13819. doi: 10.1038/srep13819. pubmed OsPIN5b modulates rice plant architecture and yield by changing auxin homeostasis, transport and distribution.Lu G, Coneva V, Casaretto JA, Ying S, Mahmood K, Liu F, Nambara E, Bi Y-M, Rothstein SJ. Plant J. 2015. 83: 913-925. pubmed Functional characterization of xanthoxin dehydrogenase in rice.Endo A, Nelson KM, Thoms K, Abrams SR, Nambara E, Sato Y.J. Plant Physiol. 2014 Sep;171(14):1231-40 pubmed The Functions of the Endosperm During Seed Germination.Yan D, Duermeyer L, Leoveanu C, Nambara E.Plant Cell Physiol. 2014 Jun; pubmed Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions.Takeuchi J, Okamoto M, Akiyama T, Muto T, Yajima S, Sue M, Seo M, Kanno Y, Kamo T, Endo A, Nambara E, Hirai N, Ohnishi T, Cutler SR, Todoroki Y.Nat. Chem. Biol. 2014 Jun;10(6):477-82 pubmed Amplification of ABA biosynthesis and signaling through a positive feedback mechanism in seeds.Nonogaki M, Sall K, Nambara E, Nonogaki H.Plant J. 2014 May;78(3):527-39 pubmed