个人简介

Ph.D. Cornell University 1979 B.Sc. University of Vermont 1973

研究领域

Comparative Genomics Evolutionary Biology Plant Biology

I am a mycologist; my specialty is the ascomycetes. I am an avid observer of the field natural history of fungi, the foundation of my undergraduate teaching (BIO 335) as well as much of my research. I am currently working on: Mechanisms of speciation in fungi. I continue to infer patterns of population divergence and speciation through retrospective studies based on population samples. This includes both agricultural plant pathogens and “wild” fungi. The new part is that, in collaboration with Jim Anderson, we are observing incipient speciation in experimental populations of both yeast and filamentous fungi. Fungal model systems are ideal for getting at genetics and genomics of this trajectory of adaptation, divergence and reproductive isolation – and for addressing key questions in speciation theory. Mechanisms of trophic preference in pathogenic fungi. New projects use genomic resources for Sclerotinia, Botrytis, and other fungi as a starting point for molecular and genetic investigation of the evolutionary divergence of trophic type among closely related taxa. Population and community dynamics of fungi in plants. This is a shift in scale to patterns and processes of fungi in planta. Current projects include lab and field experiments on facilitation /competition among maize endophytes associated with fungal tolerance of a maize allelopathic compound.

近期论文

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The Underlying Structure of Adaptation Under Strong Selection in Twelve Experimental Yeast Populations.Kohn LM, Anderson JB.Eukaryotic Cell 2014 Jul; pubmed PRP8 inteins in species of the genus Botrytis and other ascomycetes.Bokor AA, Kohn LM, Poulter RT, van Kan JA.Fungal Genet. Biol. 2012 Mar;49(3):250-61 pubmed Evidence for a common toolbox based on necrotrophy in a fungal lineage spanning necrotrophs, biotrophs, endophytes, host generalists and specialists.Andrew M, Barua R, Short SM, Kohn LM.PLoS ONE 2012;7(1):e29943 pubmed Cellular effects and epistasis among three determinants of adaptation in experimental populations of Saccharomyces cerevisiae.Parreiras LS, Kohn LM, Anderson JB.Eukaryotic Cell 2011 Oct;10(10):1348-56 pubmed Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populations.Anderson JB, Funt J, Thompson DA, Prabhu S, Socha A, Sirjusingh C, Dettman JR, Parreiras L, Guttman DS, Regev A, Kohn LM.Curr. Biol. 2010 Aug;20(15):1383-8 pubmed Genome-wide investigation of reproductive isolation in experimental lineages and natural species of Neurospora: identifying candidate regions by microarray-based genotyping and mapping.Dettman JR, Anderson JB, Kohn LM.Evolution 2010 Mar;64(3):694-709 pubmed Single nucleotide polymorphism-based diagnostic system for crop-associated Sclerotinia species.Andrew M, Kohn LM.Appl. Environ. Microbiol. 2009 Sep;75(17):5600-6 pubmed Evidence for alteration of fungal endophyte community assembly by host defense compounds.Saunders M, Kohn LM.New Phytol. 2009;182(1):229-38 pubmed Divergent adaptation promotes reproductive isolation among experimental populations of the filamentous fungus Neurospora.Dettman JR, Anderson JB, Kohn LM.BMC Evol. Biol. 2008;8:35 pubmed Marker stability throughout 400 days of in vitro hyphal growth in the filamentous ascomycete, Sclerotinia sclerotiorum.Kohn LM, Schaffer MR, Anderson JB, Grünwald NJ.Fungal Genet. Biol. 2008 May;45(5):613-7 pubmed Host-synthesized secondary compounds influence the in vitro interactions between fungal endophytes of maize.Saunders M, Kohn LM.Appl. Environ. Microbiol. 2008 Jan;74(1):136-42 pubmed