Houry, Walid A. - University of Toronto - Department of Biochemistry

个人简介

Director and principal applicant for the CIHR training program grant in “Protein Folding and Interaction Dynamics: Principles and Diseases” at the Department of Biochemistry, University of Toronto (June, 2002 – current). Director of the Analytical Ultracentrifugation Facility in the Biochemistry Department, Faculty of Medicine, Medical Science Building, University of Toronto (September, 2004 – current). Co-chair of the Basic Sciences panel of the Faculty of Medicine Research Grants Committee (Dean’s fund) at the University of Toronto (November, 2012 – current) Associate Editor of Frontiers in Protein Folding, Misfolding and Degradation, a section of Frontiers in Molecular Biosciences (January, 2014 – current). On the Editorial Board of Microbial Cell (January, 2014 – current). Editor of the book “Systems Biology & Interactomics: The Molecular Chaperones Interaction Networks in Protein Folding and Degradation”, Springer Science + Business Media (2014). Editor of The Biomedical & Life Sciences Collection, Henry Stewart Talks Series on “Protein Homeostasis” (2011 – 2012). Special Editor for the journal Biochemistry and Cell Biology, Special Issue on AAA Proteins (February, 2010). Editor of The Biomedical & Life Sciences Collection, Henry Stewart Talks Series on “Molecular Chaperones: Principles and Diseases” (2006 – 2007).

近期论文

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Nutritional Status Modulates Box C/D snoRNP Biogenesis by Regulated Subcellular Relocalization of the R2TP Complex Kakihara, Y., Makhnevych, T., Zhao, L., Tang, W., & Houry, W. A. Genome Biology 15(7): 404, 1-20 (2014) Read Structural Insights into the Inactive Subunit of the Apicoplast-Localized Caseinolytic Protease Complex of Plasmodium falciparum El Bakkouri, M., Rathore, S., Calmettes, C., Wernimont, A. K., Liu, K., Sinha, D., Asad, M., Jung, P., Hui, R., Mohmmed, A., & Houry, W. A. The Journal of Biological Chemistry 288(2), 1022-1031 (2013) Read Hsp110 is Required for Spindle Length Control Makhnevych, T., Wong, P., Pogoutse, O., Vizeacoumar, F. J., Greenblatt, J. F., Emili, A., & Houry, W. A. Journal of Cell Biology 198(4), 623-636 (2012) Read Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Novel Small Molecule Activators of the ClpP Protease Leung, E., Datti, A., Cossette, M., Goodreid, J., McCaw, S. E., Mah, M., Nakhamchik, A., Ogata, K., El Bakkouri, M., Cheng, Y.-Q., Wodak, S. J., Eger, B. T., Pai, E. F., Liu, J., Gray-Owen, S., Batey, R. A., & Houry, W. A. Chemistry & Biology 18(9), 1167–1178 (2011) Read Linkage between the Bacterial Acid Stress and Stringent Responses Revealed by the Structure of the Inducible Lysine Decarboxylase Kanjee, U., Gutsche, I., Alexopoulos, E., Zhao, B., El Bakkouri, M., Thibault, G., Liu, K., Ramachandran, S., Snider, J., Pai, E. F., & Houry, W. A. The EMBO Journal 30(5), 931-944 (2011) Read