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Organic Chemistry

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Iodine(III)-Mediated Cyclization of Unsaturated O-Alkyl Hydroxamates: Silyl-Assisted Access to α-Vinyl & α-(2-Silylvinyl) Lactams. Wardrop, D. J.; Yermolina, M. V.; Bowen, E. G. Synthesis 2012, 14, 1199-1207. Dehydrative Fragmentation of 5-Hydroxyalkyl-1H-tetrazoles: A Mild Route to Alkylidenecarbenes. Wardrop, D. J.; Komenda, J. Org. Lett. 2012, 14, 1548-1551. Methods for Direct Alkene Diamination, Old & New. de Jong, S.; Nosal, D. G.; Wardrop, D. J. Tetrahedron 2012, 68, doi 10.1016/j.tet.2012.03.036. Nitrenium Ion-Mediated Alkene Bis-Cyclofunctionalization: Total Synthesis of (-)-Swainsonine. Wardrop, D. J.; Bowen, E. G. Org. Lett. 2011, 13, 2376-2379. Diastereoselective Nitrenium Ion-Mediated Cyclofunctionalization: Total Synthesis of (+)-Castanospermine. Bowen, E. G.; Wardrop, D. J. Org. Lett. 2010, 12, 5330-5333. Discovery, Synthesis, and Biological Evaluation of a Novel Group of Selective Inhibitors of Filoviral Entry. Yermolina, M. V.; Wang, J.; M., C.; Rong, L. L.; Wardrop, D. J. J. Med. Chem. 2011, 54, 765–781. Intramolecular Oxamidation of Unsaturated O-Alkyl Hydroxamates: A Remarkably Versatile Entry to Hydroxy Lactams. Wardrop, D. J.; Bowen, E. G.; Forslund, R. E.; Sussman, A. D.; Weerasekera, S. L. J. Am. Chem. Soc. 2010, 132, 1188-1189. Synthesis and Biological Activity of Naturally Occurring Alpha-Glucosidase Inhibitors. Wardrop, D. J.; Waidyarachchi, S. L. Nat. Prod. Rep. 2010, 27, 1431-1468. Total Synthesis of the α-Glucosidase Inhibitors Schulzeine A, B, and C and a Structural Revision of Schulzeine A. Bowen, E. G.; Wardrop, D. J. J. Am. Chem. Soc. 2009, 131, 6062-6063. Reduction of Solid-Supported Olefins and Alkynes. Dickson, D. P.; Toh, C.; Lunda, M.; Yermolina, M. V.; Wardrop, D. J.; Landrie, C. L. J. Org. Chem. 2009, 74, 9535-9538. Total Synthesis of (±)-Agelastatin A, A Potent Inhibitor of Osteopontin-Mediated Neoplastic Transformations. Dickson, D. P.; Wardrop, D. J. Org. Lett. 2009, 11, 1341-1344. Total Synthesis of (±)-Magnofargesin. Wardrop, D. J.; Fritz, J. Org. Lett. 2006, 8, 3659-3662. Nitrenium Ion Azaspirocyclization−Spirodienone Cleavage: A New Synthetic Strategy for the Stereocontrolled Preparation of Highly Substituted Lactams and N-Hydroxy Lactams. Wardrop, D. J.; Burge, M. S. J. Org. Chem. 2005, 70, 10271-10284.

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