个人简介

闫学海，中国科学院过程工程研究所研究员，博士生导师，生化工程国家重点实验室副主任、介尺度科学研究中心副主任。国家自然科学基金委“优秀青年”科学基金获得者，中国化学会生物物理化学专业委员会、青年工作者委员会委员。2008年于中国科学院化学研究所获得博士学位，之后在德国马普胶体与界面研究所先后从事博士后和洪堡学者研究工作。2013年回国加入中科院过程工程研究所。 在国际重要学术期刊Chem.Soc.Rev.、J.Am.Chem.Soc.、Angew.Chem.Int.Ed.和Adv.Mater.等发表SCI论文100余篇，他引5000余次。撰写英文专著1部（Wiley-VCH出版社），英文章节5章。申报发明专利10余项。担任国际期刊ColloidsandSurfacesA副主编，ChemSystemsChem、GreenEnerg.Environ.、过程工程学报编委，Biomacromolecules、Chem.-AsianJ.客座编辑。获中国胶体与界面化学优秀青年教师奖、中国科学院优秀导师奖。

研究领域

主要从事生物分子组装和工程化研究，涉及：肽、蛋白质等生物分子自组装和超分子作用机理，生物材料可控制备技术；纳米药物和剂型、疫苗佐剂、生物催化剂以及光动力/光热治疗和免疫治疗等新技术；多尺度分级有序组装和功能调控，构建仿生功能体系和原细胞（protocell）模型，研究生化反应及能量转化机制。

肽、蛋白质等生物分子自组装和超分子作用机理，生物材料的可控制备技术 纳米药物和剂型、疫苗佐剂、生物催化剂、肿瘤成像、光动力/光热治疗和免疫治疗等新技术 多尺度分级有序组装和功能调控，构建仿生功能体系和原细胞（protocell）模型，研究生化反应及能量转化机制

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

C. Yuan, W. Ji, R. Xing, J. Li*, E. Gazit*, X. H. Yan*, Hierarchically oriented organization in supramolecular peptide crystals, Nat. Rev. Chem. 2019, 3, 567–588.Nat. Rev. Chem. 2019, 3, 567–588..JPG B. Sun, K. Tao, Y. Jia, X. H. Yan*, Q. Zou, E. Gazit*, J. Li*, Photoactive properties of supramolecular assembled short peptides, Chem. Soc. Rev. 2019, 48, 4387-4400. X. Ren, Q. Zou, C. Yuan, R. Chang, R. Xing, X. H. Yan*, The Dominant Role of Oxygen in Modulating the Chemical Evolution Pathways of Tyrosine in Peptides: Dityrosine or Melanin, Angew. Chem. Int. Ed. 2019, 58, 5872-5876.Angew. Chem. Int. Ed. 2019, 58, 5872-5876.JPG J. Han, K. Liu, R. Chang, L. Zhao, X. H. Yan*, Photooxidase-mimicking nanovesicles with superior photocatalytic activity and stability based on amphiphilic amino acid and phthalocyanine co-assembly, Angew. Chem. Int. Ed. 2019, 58, 2000-2004. L. Zhao, Y. Liu, R. Xing, X. H. Yan*, Supramolecular photothermal effects: A promising mechanism for efficient thermal conversion, Angew. Chem. Int. Ed. 2019, DOI:10.1002/anie.201909825. C. Yuan, A. Levin, W. Chen, R. Xing, Q. Zou, T. W. Herling, P. K. Challa, T. P.J. Knowles,* X. H. Yan*, Nucleation and Growth of Amino-acid and Peptide Supramolecular Polymers through Liquid-liquid Phase Separation, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201911782. R. Xing, Q. Zou, C. Yuan, L. Zhao, R. Chang, X. H. Yan*, Self-Assembling Endogenous Biliverdin as a Versatile Near-Infrared Photothermal Nanoagent for Cancer Theranostics, Adv. Mater. 2019, 31, 1900822. W. Ji, C. Yuan, S. Zilberzwige-Tal, R. Xing, P. Chakraborty, K. Tao, S. Gilead, X. H. Yan*, E. Gazit*, Metal-Ion Modulated Structural Transformation of Amyloid-Like Dipeptide Supramolecular Self-Assembly, ACS Nano 2019, 6, 7300-7309. L. Zhao, Y. Liu, R. Chang, R. Xing, X. H. Yan*, Supramolecular photothermal nanomaterials as an emerging paradigm towards precision cancer therapy, Adv. Funct. Mater. 2019, 29, 1806877. M. Cao*, R. Xing, R. Chang, Y. Wang, X. H. Yan*, Peptide-coordination Self-assembly for the Precise Design of Theranostic Nanodrugs, Coord. Chem. Rev. 2019, 397, 14-27. H. Zhang, L. Kang, Q. Zou, X. Xin*, X. H. Yan*, Coordination-assembled supramolecular nanoplatforms: Structural modulation and theranostic applications, Curr. Opin. Biotechnol. 2019, 58, 45-52. S. Li, Q. Zou, R. Xing, T. Govindaraju, R. Fakhrullin, X. H. Yan*, Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics, Theranostics 2019, 9, 3249-3261. W. Ji, C. Yuan, P. Chakraborty, S. Gilead, X. H. Yan*, E. Gazit*, Stoichiometry-controlled secondary structure transition of amyloid-derived supramolecular dipeptide co-assemblies, Communications Chemistry 2019, 2, 65. S. Li, Y. Liu, R. Xing, X. H. Yan*, Covalent assembled dipeptide nanoparticles with adjustable fluorescence emission for multi-color bio-imaging, ChemBioChem 2019, 20, 555-560. L. Zhao, Q. Zou, X. H. Yan*, Self-Assembling Peptide-Based Nanoarchitectonics, Bull Chem. Soc. Jpn. 2019, 92, 70-79. L. Zhao, S. Li, Y. Liu, R. Xing, X. H. Yan*, Kinetically Controlled Self-Assembly of Phthalocyanine-Peptide Conjugate Nanofibrils Enabling Super-Large Redshifted Absorption, CCS Chem. 2019, 1, 173-180. J. Li, R. Xing, S. Bai*, X. H. Yan*, Recent advances of self-assembling peptide-based hydrogels for biomedical applications, Soft Matter 2019, 15, 1704-1715. J. Li, A. Wang, P. Ren, X. H. Yan*, S. Bai*, One-step co-assembly method to fabricate photosensitive peptide nanoparticles for two-photon photodynamic therapy, Chem. Comm. 2019, 55, 3191-3194. M. Yang, C. Yuan, G. Shen, R. Chang, R. Xing, X. H. Yan*, Cyclic dipeptide nanoribbons formed by dye-mediated hydrophobic self-assembly for cancer chemotherapy, J. Colloid Interface Sci. 2019, 557, 458-464. M. Yang, R. Xing, G. Shen, C. Yuan, X. H. Yan*, A versatile cyclic dipeptide hydrogelator: Self-assembly and rheology in various physiological conditions, Colloid Surf. A-Physicochem. Eng. Asp. 2019, 572, 259-265.