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个人简介

1989-1994 美国哈佛大学,化学系,博士 1994-1999 新加坡国立大学,助理教授 1999-2004 新加坡国立大学,副教授 2004-2005 新加坡国立大学,教授 2005-2008 新加坡南洋理工大学,终身教授,化学与生物系,系主任 2008-2012 新加坡南洋理工大学,物理与数学科学学院,副院长 2005- 新加坡南洋理工大学,终身教授 罗德平教授,国际著名化学家,新加坡科学院院士、马来西亚科学院院士,原新加坡化学学院建院院长。 学术成绩 2017 Yoshida prize(International Organic Chemistry Foundation) 2017 Assoc. Editor of The Journal of Organic Chemistry 2004-Present Advisory board member of Chem. Commun.; Synlett.; Synthesis; ChemCatChem; Heterocycles and etc.;Assoc. Editor of Asian Journal of Chemistry. 2014 Fellow, Royal Society of Chemistry ( RSC). 2010 Fellow, Academia of Sciences, Malaysia. 2010 GSK-SNIC Award in Organic Chemistry. 2010 Excellence Teaching Award, School of Physical and Mathematic Science (SPMS), NTU.

研究领域

绿色化学;不对称有机合成反应;生物质分子的有机转化;有机合成化学新反应、新概念的研究;具有生物活性的复杂天然产物和药物的全合成研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Jiang, B.; Zhao, M.; Li, S.-S; Xu, Y.-H.; Loh, T.-P. Macrolide Synthesis trough Intramolecular Oxidative Cross-Coupling of Alkenes, Angew.Chem. Int. Ed. 2017, DOI: 10.1002/anie.201710601. 2. Liang, Q.-J.; Yang, C.; Meng, F.-F.; Jiang, B.; Xu, Y.-H.; Loh, T.-P. Chelation versus Non-Chelation Control in the Stereoselective Alkenyl sp2 C-H Bond Functionalization Reaction. Angew. Chem. Int. Ed. 2017, 129, 5173. 3. Shen, L.; Zhao, K.; Doitomi, K.; Ganguly, R.; Li, Y.-X. Shen, Z.-L; Hirao, H.; Loh, T.-P. Lewis Acid-Catalyzed Selective [2 + 2]-Cycloaddition and Dearomatizing Cascade Reaction of Aryl Alkynes with Acrylates. J. Am. Chem. Soc. 2017, 139, 13570. 4. Lan, Y.; Chang,X.-H.; Fan, P.; Shan,C.-C. Liu, Z.-B.; Loh, T.-P.; Xu,Y.-H. Copper-Catalyzed Silylperoxidation Reaction of α,β-Unsaturated Ketones, Esters, Amides, and Conjugated Enynes. ACS. Catal. 2017, 7, 7120. 5. Zhao, K.; Shen, L.; Shen, Z.-L.; Loh, T.-P. Transition metal-catalyzed cross-coupling reactions using organoindium reagents. Chem. Soc. Rev. 2017, 46, 586. 6. Wang, C.-Q.; Ye, L.; Feng, C.; Loh, T. -P. C-F Bond Cleavage Enabled Redox-Neutral [4+1] Annulation via C-H Bond Activation, J. Am. Chem. Soc. 2017, 139, 1762. 7. Tian, P.; Wang, C.-Q.; Cai, S.-H.; Song, S.; Ye, L.; Feng, C.; Loh, T. -P. Fˉ Nucleophilic-Addition-Induced Allylic Alkylation, J. Am. Chem. Soc. 2016, 138, 15869. 8. Cai, S.-H.; Xie, J.-H.; Ye, L.; Feng, C.; Loh, T. -P. isible-Light-Promoted Carboimination of Unactivated Alkenes for the Synthesis of Densely Functionalized Pyrroline Derivatives, ACS Cat. 2016, 6, 5571. 9. Hu, X.-H.; Yang, X.-F.; Loh, T.-P. Selective Alkenylation and Hydroalkenylation of Enol Phosphates through Direct C-H Functionalization. Angew. Chem. Int. Ed. 2015, 127, 15755. 10. Lu, M.-Z.; Wang, C.-Q.; Loh, T.-P. Copper-Catalyzed Vicinal Oxyazidation and Diazidation of Styrenes under Mild Conditions: Access to Alkyl Azides. Org. Lett. 2015, 17, 6110. 11. Wang, M.; Liu, Z.-L.; Zhang, X.; Tian, P.-P.; Xu, Y.-H.; Loh, T.-P. Synthesis of Highly Substituted Racemic and Enantioenriched Allenylsilanes via Copper-Catalyzed Hydrosilylation of (Z)-2-Alken-4-ynoates with Silylboronate. J. Am. Chem. Soc. 2015, 137, 14830. 12. Zhou, J.-H.; Jiang, B.; Meng, F.-F.; Xu, Y.-H.; Loh, T.-P. B(C6F5)3: A New Class of Strong and Bulky Lewis Acid for Exo-Selective Intermolecular Diels–Alder Reactions of Unreactive Acyclic Dienes with α,β-Enals. Org. Lett. 2015, 17, 4432. 13. Zhang, M.-X.; Hu, X.-H.; Xu, Y.-H.; Loh, T.-P. Selective Dealkylation of Alkyl Aryl Ethers. Asian J. Org. Chem. 2015, 4, 1047. 14. Qiu, S.-Q.; Xu, Y.-H.; Loh, T.-P. Palladium-Catalyzed Intermolecular Oxyarylation of Vinylacetates with Retention of an Alkenyl Moiety. Org. Lett. 2015, 17, 3462. 15. Lu, P.; Feng, C.; Loh, T.-P. Divergent Functionalization of Indoles with Acryloyl Silanes via Rhodium-Catalyzed C-H Activation. Org. Lett. 2015, 17, 3210. 16. Chen, Y.-C.; Zhu, M.-K.; Loh, T.-P. Csp3–Csp3 Bond Cleavage in the Palladium-Catalyzed Aminohydroxylation of Allylic Hydrazones Using Atmospheric Oxygen as the Sole Oxidant. Org. Lett. 2015, 17, 2712. 17. Zhang, X.; Wang, M.; Ding, R.; Xu, Y.-H.; Loh, T.-P. Highly Enantioselective and Anti-Diastereoselective Catalytic Intermolecular Glyoxylate–Ene Reactions: Effect of the Geometrical Isomers of Alkenes. Org. Lett. 2015, 17, 2736. 18. Koh, P.-F.; Loh, T.-P. Synthesis of biologically active natural products, aspergillides A and B, entirely from biomass derived platform chemicals. Green Chem. 2015, 17, 3746. 19. Tian, P.; Feng, C.; Loh, T.-P. Rhodium-catalysed C(sp2)-C(sp2) bond formation via C-H/C-F activation. Nat. Commun. 2015, 6, 7472. 20. Tian, P.-P.; Cai, S.-H.; Liang, Q.-J.; Zhou, X.-Y.; Xu, Y.-H.; Loh, T.-P., Palladium-Catalyzed Difunctionalization of Internal Alkynes via Highly Regioselective 6-Endo Cyclization and Alkenylation of Enynoates: Synthesis of Multisubstituted Pyrones. Org. Lett. 2015, 17, 1636. 21. Isobe, M.; Nishida, A.; Choo, Y.-M.; Rahman, N. A.; Ploypradith, P.; Ruchirawat, S.; Lin, G.-Q.; Li, A.; Yao, Z.-J.; Uang, B.-J.; Liao, C.-C.; Chiu, P.; Kim, B. M.; Loh, T.-P., The Last and Next Decades of the Asian Core Program on Cutting-Edge Organic Chemistry in Asia. Chem. Asian J. 2015, 10, 790. 22. Yang, X.-F.; Hu, X.-H.; Loh, T.-P., Expedient Synthesis of Pyrroloquinolinones by Rh-Catalyzed Annulation of N-Carbamoyl Indolines with Alkynes through a Directed C–H Functionalization/C–N Cleavage Sequence. Org. Lett. 2015, 17, 1481. 23. Pankajakshan, S.; Chng, Z. G.; Ganguly, R.; Loh, T.-P., Copper-catalyzed aerobic carboxygenation and N-arylation of [1,2,3]triazolo[1,5-a]pyridines towards pyridinium triazolinone ylides. Chem. Commun. 2015, 51, 5929. 24. Zhang, L.-Y.; Zhou, J.-H.; Xu, Y.-H.; Loh, T.-P., Copper-Catalyzed Enantioselective Conjugate Addition of Grignard Reagents to Methyl 4,4,4-Trifluorocrotonate: Synthesis of Enantioenriched Trifluoromethylated Compounds. Chem. Asian J. 2015, 10, 844. 25. Zhang, S.; Li, L.; Hu, Y.; Zha, Z.; Wang, Z.; Loh, T.-P., Bifunctional Amino Sulfonohydrazide Catalyzed Direct Asymmetric Mannich Reaction of Cyclic Ketimines with Ketones: Highly Diastereo- and Enantioselective Construction of Quaternary Carbon Stereocenters. Org. Lett. 2015, 17, 1050. 26. Hu, X.-H.; Zhang, J.; Yang, X.-F.; Xu, Y.-H.; Loh, T.-P., Stereo- and Chemoselective Cross-Coupling between Two Electron-Deficient Acrylates: An Efficient Route to (Z,E)-Muconate Derivatives. J. Am. Chem. Soc. 2015, 137, 3169. 27. Yang, X.-F.; Hu, X.-H.; Feng, C.; Loh, T.-P., Rhodium(iii)-catalyzed C7-position C-H alkenylation and alkynylation of indolines. Chem. Commun. 2015, 51, 2532. 28. Wang, M.; Zhang, X.; Zhuang, Y.-X.; Xu, Y.-H.; Loh, T.-P., Pd-Catalyzed Intramolecular C–N Bond Cleavage, 1,4-Migration, sp3 C–H Activation, and Heck Reaction: Four Controllable Diverse Pathways Depending on the Judicious Choice of the Base and Ligand. J. Am. Chem. Soc. 2015, 137, 1341. 29. Cheng, J.-K.; Loh, T.-P. Copper- and Cobalt-Catalyzed Direct Coupling of sp3 α-Carbon of Alcohols with Alkenes and Hydroperoxides. J. Am. Chem. Soc. 2015, 137, 42. 30. Feng, C.; Feng, D.; Loh, T.-P. Rhodium(iii)-catalyzed C-H allylation of electron-deficient alkenes with allyl acetates. Chem. Commun. 2015, 51, 342.

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