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研究领域

Coordination Chemistry, Photophysics and Photochemistry, Photodynamic Therapy, DNA Topology

近期论文

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Near-Infrared-Emitting Heteroleptic Cationic Iridium Complexes Derived from 2,3-Diphenylbenzo[g]quinoxaline as In Vitro Theranostic Photodynamic Therapy Agents: Dalton Trans. Accepted May, 2017. Novel Osmium-based Coordination Complexes as Photosensitizers for Panchromatic Photodynamic Therapy: Photochem. and Photobio., Accepted March, 2017. DOI: 10.1111/php.12767 Synthesis and Photobiological Activity of Ru(II) Dyads Derived from Pyrrole-2-carboxylate Thionoesters: Inorg. Chem., 2017, 56, 4121 - 4132. DOI: 10.1021/acs.inorgchem.7b00072 π‐Expansive Heteroleptic Ruthenium(II) Complexes as Reverse Saturable Absorbers and Photosensitizers for Photodynamic Therapy: Inorg. Chem., 2017, 56, 3245-3259. DOI: 10.1021/acs.inorgchem.6b02624 Increasing the Triplet Lifetime and Extending the Ground-State Absorption of Cationic Biscyclometalated Ir(III) Complexes by Tuning Ligand π-Conjugation for Applications in Reverse Saturable Absorption and Photodynamic Therapy: Dalt. Trans., 2016, 45, 16366-16378. DOI: 10.1039/c6dt02416e Influence of Protonation State on the Excited State Dynamics of a Photobiologically Active Ru(II) Dyad: J. Phys. Chem. A, 2016, 120, 6379-6388. DOI: 10.1021/acs.jpca.6b05957 Strained Ruthenium Metal-Organic Dyads as Photocisplatin Agents with Dual Action: J. Inorg. Biochem. 2016, 158, 45-54. DOI: 10.1016/j.jinorgbio.2016.01.009 A Spectroscopic Study of Substituted Anthranilic Acids as Sensitive Environmental Probes for Detecting Cancer Cells: Bioorg. Med. Chem., 2016, 24, 929-937. DOI: 10.1016/j.bmc.2015.12.044 Organometallic Ru(II) Photosensitizers Derived from π‐Expansive Cyclometalating Ligands: Surprising Theranostic PDT Effects: Inorg. Chem., 2016, 55, 83–95. DOI: 10.1021/acs.inorgchem.5b01838 Isolation and Synthetic Diversification of Jadomycin 4‐Amino‐L‐phenylalanine: J. Nat. Prod., 2015, 78, 1208-1214. DOI: 10.1021/np5009398 Photophysics of Ru(II) Dyads Derived from Pyrenyl-Substitued Imidazo[4,5-f][1,10]Phenanthroline Ligands: J. Phys. Chem. A, 2015, 119, 3986–3994. DOI:10.1021/acs.jpca.5b01737 Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis: J. Am. Chem. Soc., 2015, 137, 3271-3275. DOI:10.1021/ja5114672 Ru(II) Dyads Derived from α-Oligothiophenes: a New Class of Potent and Versatile Photosensitizers for PDT: Coord. Chem. Rev., 2015, 282-283, 127-138. DOI 10.1016/j.ccr.2014.04.012 Ru(II) Dyads Derived from 2-(1-Pyrenyl)-1H-imidazo[4,5-f][1,10]phenanthroline: Versatile Photosensitizers for Photodynamic Applications: J. Phys. Chem. A, 2014, 118, 10507-10521. DOI:10.1021/jp504330s Synthesis and Antimalarial Activity of Prodigiosenes: Org. Biomol. Chem., 2014, 12, 4132-4142. DOI:10.1039/C3OB42548G In Vitro Multiwavelength PDT with 3IL States: Teaching Old Molecules New Tricks: Inorg. Chem., 2014, 53, 4548−4559. DOI 10.1021/ic5002368 Exploitation of Long-Lived 3IL Excited States for Metal−Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model: J. Am. Chem. Soc., 2013, 135, 17161−17175. DOI 10.1021/ja408426z Synthetic prodigiosenes and the influence of C-ring substitution on DNA cleavage, transmembrane chloride transport and basicity: Org. Biomol. Chem., 2013, 11, 3834–3845. DOI 10.1039/c3ob40477c Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru(II)-based type I/type II photosensitizers: Photodiag. Photodyn. Ther., 2013, 10, 615-625. DOI 10.1016/j.pdpdt.2013.07.001 Investigations regarding the utility of prodigiosenes to treat leukemia: Org. Biomol. Chem., 2012, 11, 62-68. DOI 10.1039/c2ob26535d Synthetic diversification of natural products: semi-synthesis and evaluation of triazole jadomycins: Chem. Sci., 2012, 3, 1640–1644. DOI 10.1039/c2sc00663d Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies: Med. Chem. Commun., 2011, 2, 274–277. DOI 10.1039/c0md00211a Copper-mediated nuclease activity of jadomycin B: Bioorg. Med. Chem., 2011, 19, 3357–3360. DOI 10.1021/ic902427r Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine: J. Nat. Prod. 2011, 74, 2420−2424. DOI 10.1021/np200689w Photobiological Activity of Ru(II) Dyads Based on (Pyren-1-yl)ethynyl Derivatives of 1,10-Phenanthroline: Inorg. Chem. 2010, 49, 2889–2900. DOI: 10.1021/ic902427r

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