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Vila-Leahey A, Oldford S, Marignani PA, Haidl I and Marshall JS, (2016) Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice. Oncoimmunology 10;5(7):e1151591 [PubMed] [Article] Nahta, R., Andrade-Vieira R., multi-author., Marignani PA, (2015) Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis 36 (Suppl 1):S2-S18 [PubMed] [Article] Andrade-Vieira, R, Marignani PA, multi-author, (2015) Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead Carcinogenesis Vol 36 (Suppl):S254-S296 [PubMed] [Article] Vila-Leahey, A., Oldford, S., Marignani, PA. and Marshall, JS., (2015) Histamine receptor 2 blockade reduces breast tumor development and metastasis The Journal of Immunology vol.194 (1 Supplement):210.12 [Article] Andrade-Vieira, R., Bentley H, Goguen, D. Bowen C and Marignani P, (2014) Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss. Oncotarget Published November 25, 2014: [PubMed] Rafaela Andrade-Vieira, Jae H Han and Paola A Marignani, (2013) Omega-3 polyunsaturated fatty acid promotes the inhibition of glycolytic enzymes and mTOR signaling by regulating the tumor suppressor LKB1. Cancer Biology and Therapy 14 (11):1-9 [PubMed] [Article] Andrade-Vieira RA, Colp P., Xu, Z., Marignani PA, (2013) Loss of lkb1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways. Plos One 8(2):e56567 [PubMed] [Article] Marignani PA and Sanchez-Cespedes M, (2010) The tumour suppressor role of LKB1 in human cancer. Emerging Signaling Pathways in Tumor Biology. :71-94 Nath-Sain, S and Marignani, P. A., (2009) LKB1 catalytic activity contributes to estrogen receptor alpha signaling. Molecular Biology of the Cell 20:2785-2795 [PubMed] Soundararajan, R., Robertson, G., and Marignani, P. A., (2009) Triptolide: an inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells. Cancer Biology and Therapy 8:2052-2060 [PubMed] Arora, P.D, Marignani, P.A, and McCulloch, C.A. , (2008) Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2. Am J Physiol Cell Physiol. 295(1):C130-7 [PubMed] Scott KD, Nath-Sain S, Agnew MD and Marignani PA. , (2007) LKB1 catalytic-deficient mutants enhance cyclin D1 expression. Cancer Research 67(12):5622-5627. [PubMed] Marignani, P. A., Scott, K.D., Bagnulo, R., Stella, A., Guanti, G., Simone, C., Resta, N., (2007) Novel splice isoforms of STRADa differentially affect LKB1 activity, complex assembly and sub-cellular localization. Cancer Biology and Therapy 6(9):1627-1631 [PubMed] Marignani, P. A., (2005) LKB1, the multi-tasking tumour suppressor kinase. Journal of Clinical Pathology 58:15-19 [PubMed] Scheid, M., Marignani PA., Woodgett J., (2002) Multiple Phosphoinositide-3-kinase dependent steps in the activation of protein kinase B. Molecular and Cellular Biology 22:6247-6260 [PubMed] Marignani PA., Kanai F and Carpenter CL, (2001) LKB1 associates with Brg1 and is necessary for Brg1 induced growth arrest. Journal of Biological Chemistry 276:32415-32418 [PubMed] Marignani PA and Carpenter CL, (2001) Vav2 is required for cell spreading. Journal of Cell Biology 154:177-186 [PubMed] Ohashi M., Kanai F., Tateishi K.,Taniguchi H., Marignani PA., Yoshida Y., Shiratori Y., Hamada H., Omata H., (2001) Target gene therapy for alpha-fetoprotein producing hepatocellularcarcinoma by E1B55k-attenuated adenovirus. BBRC 282:529-535 [PubMed] Kanai F., Marignani PA., Sarbassova D., Yagi R., Hall RA., Donowitz M., Hisaminato A., Fujiwara T., Ito Y., Cantley LC. and Yaffe MB., (2000) TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. Embo. J. 19:6778-6791 [PubMed] Kanai, F., Ohashi, M., Marignani, P. A., Shiratori, Y., Hamada, H., and Omata, M., (2000) Adenovirus-mediatd drug-sensitivity gene therapy for hepatocellular carcinoma. Methods Mol Med. 45:257-269 [PubMed] Methods Mol. Med. 45:257-269 [PubMed] Nishikawa K., Toker A., Wong K., Marignani PA., Johannes F-J and Cantley LC., (1998) Association of protein kinase C with Type II phosphatidylinositol 4-kinase and Type I phosphatidyl-4-phosphate 5-kinase. Journal of Biological Chemistry 273:23126-23133 [PubMed] Sebaldt RJ and Marignani P., (1997) Diradylglycerol formation is altered by n-3 highly unsaturated fatty acids, with differences between eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids. Adv Exp Med Biol. 400 :937-45 [PubMed] Marignani PA, (1997) Effects of Omega-3 Polyunsaturated Fatty Acids on the Formation of sn-1,2-Diradylglycerol, Cytokine Secretion and Regulation of Protein Kinase C Activity. Doctoral Thesis, McMaster University, Canada : Marignani PA, Epand RM and Sebaldt RJ., (1996) Acyl chain dependence of diacylglycerol activation of protein kinase C activity in vitro. Biochemical and Biophysical Research Communication 225:469-473 [PubMed] Marignani PA and Sebaldt RJ., (1996) The formation of diradylglycerol molecular species in murine peritoneal macrophages varies dose-dependently with purified eicosapentaenoic and docosahexaenoic ethyl esters. Journal of Nutrition 126:2738-2745 [PubMed]