BATEY, Robert - University of Toronto - Department of Chemistry

研究领域

Our research interests are in the general area of organic chemistry, including the development of synthetic methods and reagents, the total synthesis of natural products, and the discovery and design of small molecules having useful biological function. For more information on our research and group please use the links at the top of the page.

近期论文

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"Total Synthesis and Bacterial Testing of the Antibiotic A54556 Cyclic Acyldepsipeptides Isolated from Streptomyces hawaiiensis.", Goodreid, J. D.; Wong, K.; Leung, E.; McCaw, S. E.; Gray-Owen, S.; Lough, A.; Houry, W. A.; Batey, R. A. J. Nat. Prod. 2014, 77, 2170–2181. DOI: 10.1021/np500158q "Organoboron-based Allylation Approach to the Total Synthesis of the Medium-ring Dilactone (+)-Antimycin A1b.", Janetzko, J.; Batey, R. A. J. Org. Chem. 2014, 79, 943–954. doi: 10.1021/jo501134d "An Organotrifluoroborate-based Convergent Total Synthesis of the Potent Cancer Cell Growth Inhibitory Depsipeptides Kitastatin and Respirantin.", Beveridge, R. E.; Batey, R. A. Org. Lett. 2014, 16, 2322–2325. doi: 10.1021/ol500484f "Amidation Reactions from the Direct Coupling of Metal Carboxylate Salts with Amines.", Goodreid, J. D.; Duspara, P. A.; Bosch, C.; Batey, R. A. J. Org. Chem. 2014, 79, 943–954. doi: 10.1021/jo402374c "A Short Total Synthesis of the Marine Sponge Pyrrole-2-aminoimidazole Alkaloid (±)-Agelastatin A.", Duspara, P. A.; Batey, R. A. Angew. Chem. Int. Ed. 2013, 52, 10862–10866. doi: 10.1002/anie.201304759 "Synthesis of 2-Bromo-1-Aryl-1H-indenes via a Domino 2π-Electrocyclic Ring-opening / 4π -Electrocyclization Reaction of 1,2-Diaryl Substituted Gem-Dibromocyclopropanes.", Rosocha, G.; Batey, R. A. Tetrahedron 2013, 69, 8758–8768. doi: 10.1016/j.tet.2013.07.086 "Copper Catalyzed Non-Decarboxylative Cross Coupling of Alkenyltrifluoroborate Salts with Carboxylic Acids or Carboxylates: Synthesis of Enol Esters.", Huang, F.; Quach, T. D.; Batey, R. A. Org. Lett. 2013, 15, 3150–3153. doi: 10.1021/ol4013712 "Total Synthesis of the Cytotoxic Enehydrazide Natural Products Hydrazidomycins A and B by a Carbazate Addition / Peterson Olefination Approach.", Beveridge, R. E.; Batey, R. A. Org. Lett. 2013, 15, 3086–3089. doi: 10.1021/ol401275f "ConfChem Conference on Educating the Next Generation: Green and Sustainable Chemistry – Greening the Organic Curriculum: Development of an Undergraduate Catalytic Chemistry Course.", Dicks A. P.; Batey, R. A. J. Chem. Educ. 2013, 90, 519-520. doi: 10.1021/ed2004998 "A Formal Hetero Diels-Alder Approach to the Synthesis of Chromans (3,4-Dihydrobenzopyrans) using Oxonium Ion Chemistry: The Oxa-Povarov Reaction.", Taylor, R. R. R.; Batey, R. A. J. Org. Chem. 2013, 78, 1404-1420. doi: 10.1021/jo302328s "Mild Double Allylboration Reactions of Nitriles and Anhydrides Using Potassium Allyltrifluoroborate.", Ramadhar, T. R.; Bansagi, J.; Batey, R. A. J. Org. Chem. 2013, 78, 1216-1221. doi: 10.1021/jo302194n "Regio- and Stereoselective C–2 Allylation and Crotylation of Indoles with Potassium Organotrifluoroborate Salts.", Nowrouzi, F.; Batey, R. A. Angew. Chem. Int. Ed 2012, 52, 892-895. doi: 10.1002/anie.201207978 "The Synthesis and Reactivity of N-Alkyl Carbamoylimidazoles: Development of N-Methyl Carbamoylimidazole as a Methyl Isocyanate Equivalent.", Duspara, P. A.; Sadequl Islam, Md.; Lough, A. J.; Batey, R. A. J. Org. Chem. 2012, 77, 10362-10368. doi: 10.1021/jo302084a "Effect of Acid Catalysis on the Direct Electrophilic Fluorination of Ketones and Enamides using Selectfluor™.", Liu, J.; Chan, J.; Bryant, C. M.; Duspara, P.; Lee, E. E.; Powell, D.; Yang, H.; Liu, Z.; Walpole, C.; Roberts, E.; Batey, R. A. Tetrahedron Lett. 2012, 53, 2971-2975. doi: 10.1016/j.tetlet.2012.03.074 "Diastereoselective Synthesis of Fluorinated Piperidine Quinazoline Spirocycles as iNOS Selective Inhibitors.", Walpole, C.; Liu, Z.; Lee, E. E.; Yang, H.; Zhou, F.; Mackintosh, N.; Sjogren, M.; Taylor, D.; Shen, J.; Batey, R. A. Tetrahedron Lett. 2012, 53, 2942-2947. doi: 10.1016/j.tetlet.2012.03.050