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个人简介

Ben L. Feringa obtained his PhD degree at the University of Groningen in the Netherlands under the guidance of Professor Hans Wynberg. After working as a research scientist at Shell in the Netherlands and at the Shell Biosciences Centre in the UK, he was appointed lecturer and in 1988 full professor at the University of Groningen and named the Jacobus H. van't Hoff Distinguished Professor of Molecular Sciences in 2004. He was elected Foreign Honory member of the American Academy of Arts and Sciences and is member and vice-president of the Royal Netherlands Academy of Sciences. In 2008 he was appointed Academy Professor and was knighted by Her Majesty the Queen of the Netherlands. Feringa's research has been recognized with a number of awards including the Koerber European Science Award (2003), the Spinoza Award (2004), the Prelog gold medal (2005), the Norrish Award of the ACS (2007), the Paracelsus medal (2008), the Chirality medal (2009),the RSC Organic Stereochemistry Award (2011), Humboldt Award (2012), the Grand Prix Scientifique Cino del Duca (French Academy 2012), the Marie Curie medal (2013) and the Nagoya Gold Medal (2013). The research interest includes stereochemistry, organic synthesis, asymmetric catalysis, optopharma, molecular switches and motors, self-assembly and molecular nanosystems. Academic and industrial career 1969-1978 Undergraduate and graduate studies in chemistry, University of Groningen PhD at Department of Organic Chemistry, University of Groningen, Thesis: Asymmetric Oxidations of Phenols; supervisor Prof. Dr. Hans Wynberg 1978-1982 Research Chemist (organic synthesis, oxidation processes, photochemistry), Royal Dutch Shell, Shell Laboratories, Amsterdam. 1979-1982 Lecturer Amsterdam (Hogere Analistenschool). 1982-1983 Research Chemist (Bioorganic Chemistry), Shell Biosciences Laboratories, Sittingbourne, UK. 1983-1984 Project Leader Homogeneous Catalysis, Shell Research Laboratories, Amsterdam. 1984-1988 Lecturer Organic Chemistry, University of Groningen. 1988- Appointed successor of Prof. Dr. H. Wynberg; chair of Organic Chemistry, Professor of Organic Chemistry, University of Groningen. 1991-1995 Chairman Department Organic and Molecular Inorganic Chemistry 2003-2011 Director Stratingh Institute for Chemistry 2003- Jacobus H. van 't Hoff Distinguished Professor of Molecular Sciences 2008- Academy Professor; Royal Netherlands Academy of Sciences 2011- Hans Fischer Honorary Fellow, Institute for Advanced Studies, TU Muenchen

研究领域

The research program of the Feringa group is focussed on synthetic organic chemistry. Over the years a unique expertise in stereochemistry has been acquired. Inspired by nature's principles of molecular assembly, recognition, transport, motion and catalysis, the goal is to exploit the full potential of synthetic chemistry to create new structures and functions. A major part of the research is directed towards nanotechnology and novel functional materials, such as molecular switches and motors. A second part of the program deals with the development (and application in chemical biology) of novel stereoselective synthesis methods and asymmetric catalysis. Control of chirality is the guiding principle in both programs.

近期论文

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Hydrazone-based boron difluoride complexes as triplet photosensitizers for singlet oxygen generation Sven van Vliet, Johannes G. H. Hermens, Youxin Fu, Lukas Pfeifer and Ben L. Feringa, Chem. Commun. 2023, Advance Article (DOI: 10.1039/D2CC05336E) Photoswitchable, Water-Soluble Bisazobenzene Cross-Linkers with Enhanced Properties for Biological Applications Jana Volarić, Sebastian Thallmair, Ben L. Feringa and Wiktor Szymanski, ChemPhotoChem 2022, 6, e20220017 (DOI: 10.1002/cptc.202200170) Incorporating sulfur into redox-active reagents and materials Sebastian B. Beil, Marco B. S. Wonink, Ben L. Feringa, Tetrahedron 2023, 133262 (DOI: 10.1016/j.tet.2023.133262) Turning Enantiomeric Relationships into Diastereomeric Ones: Self-Resolving α-Ureidophosphonates and Their Organocatalytic Enantioselective Synthesis.Vanda Dašková, Damián Padín and Ben L. Feringa, J. Am. Chem. Soc. 2022, 144, 51, 23603–23613 (DOI: 10.1021/jacs.2c10911) A sustainable polymer and coating system based on renewable raw materials Johannes G. H. Hermens, Thomas Freese, Georgios Alachouzos, Mathieu L. Lepage, Keimpe J. van den Berg, Niels Elders and Ben L. Feringa, Green Chem. 2022, 24, 9772–9780 (DOI: 10.1039/D2GC03657F) Light-fueled transformations of a dynamic cage-based molecular system Marco Ovalle, Michael Kathan, Ryojun Toyoda, Charlotte N. Stindt, Stefano Crespi, Ben L Feringa, Angew. Chem. Int. Ed. 2023, Accepted article. (DOI: 10.1002/anie.202214495) Nanoporous Films with Oriented Arrays of Molecular Motors for Light-Controlled Adsorption and Diffusion Yunzhe Jiang, Wojciech Danowski, Ben L. Feringa and Lars Heinke, Angew. Chem. Int. Ed. 2023, 62, 3, e202214202 (DOI: 10.1002/anie.202214202) Designing light-driven rotary molecular motors Daisy R. S. Pooler, Anouk S. Lubbe, Stefano Crespi and Ben L. Feringa, Chem. Sci. 2021, 12, 14964-14986 (DOI: 10.1039/D1SC04781G) Photoresponsive Supramolecular Polymers: From Light-controlled Small Molecules to Smart Materials Fan Xu and Ben L. Feringa, Adv. Mater. 2022, early view (DOI: 10.1002/adma.202204413) Design and Synthesis of Visible-Light-Responsive Azobenzene Building Blocks for Chemical Biology Jana Volarić, Jeffrey Buter, Albert M. Schulte, Keimpe-Oeds van den Berg, Eduardo Santamaría-Aranda, Wiktor Szymanski and Ben L. Feringa, J. Org. Chem. 2022, early view. (DOI: 10.1021/acs.joc.2c01777) Coupled Rocking Motion in a Light-Driven Rotary Molecular Motor Cosima Stähler, Daisy R. S. Pooler, Romain Costil, Dhruv Sudan, Pieter van der Meulen, Ryojun Toyoda and Ben L. Feringa, J. Org. Chem. 2022, early view. (DOI: 10.1021/acs.joc.2c01830) Synergistic interplay between photoisomerization and photoluminescence in a light-driven rotary molecular motor Ryojun Toyoda, Nong V. Hoang, Kiana Gholamjani Moghaddam, Stefano Crespi, Daisy R. S. Pooler, Shirin Faraji, Maxim S. Pshenichnikov and Ben L. Feringa, Nat. Commun. 2022, 13, 5765 (DOI: 10.1038/s41467-022-33177-0) Development of a modular photoreactor for the upscaling of continuous flow photochemistry Johannes G. H. Hermens, Mathieu L. Lepage, Arjan Kloekhorst, Erik Keller, Robin Bloem, Maurice Meijer and Ben L. Feringa, React. Chem. Eng. 2022, 7, 2280-2284 (DOI: 10.1039/D2RE00310D) Enantiodivergent epoxidation of alkenes with a photoswitchable phosphate manganese-salen complex Xiaofei Chen, Pieter J. Gilissen, Paul Tinnemans, Nicolas Vanthuyne, Floris P. J. T. Rutjes, Ben L. Feringa, Johannes A. A. W. Elemans and Roeland J. M. Nolte, Nat. Synth. 2022, 1, 872-882 (DOI: 10.1038/s44160-022-00157-7) A Chemically Recyclable Crosslinked Polymer Network Enabled by Orthogonal Dynamic Covalent Chemistry Yuanxin Deng, Qi Zhang, Da-Hui Qu, He Tian and Ben L. Feringa, Angew. Chem. Int. Ed. 2022, 61, 39, e202209100 (DOI: 10.1002/anie.202209100) Visible light activated BINOL-derived chiroptical switches based on boron integrated hydrazone complexes Sven van Vliet, Georgios Alachouzos, Folkert de Vries, Lukas Pfeifer and Ben L. Feringa, Chem. Sci. 2022, 13, 9713-9718. (DOI: 10.1039/D2SC03518A) The Influence of Strain on the Rotation of an Artificial Molecular Motor Michael Kathan, Stefano Crespi, Axel Troncossi, Charlotte N. Stindt, Ryojun Toyoda and Ben L. Feringa, Angew. Chem. Int. Ed. 2022, 61, 34, e202205801 (DOI: 10.1002/anie.202205801) Mechanistic Insight into Supramolecular Polymerization in Water Tunable by Molecular Geometry Fan Xu, Stefano Crespi, Lukas Pfeifer, Marc C. A. Stuart and Ben L. Feringa, CCS Chem. 2022, 4, 2212-2220. (DOI: 10.31635/ccschem.022.202201821) Intrinsically unidirectional chemically fuelled rotary molecular motors Ke Mo, Yu Zhang, Zheng Dong, Yuhang Yang, Xiaoqiang Ma, Ben L. Feringa and Depeng Zhao, Nature 2022, 609, 293-298 (DOI: 10.1038/s41586-022-05033-0) Strategy for Engineering High Photolysis Efficiency of Photocleavable Protecting Groups through Cation Stabilization Albert M. Schulte, Georgios Alachouzos, Wiktor Szymański and Ben L. Feringa, J. Am. Chem. Soc. 2022, 144, 27, 12421–12430 (DOI: 10.1021/jacs.2c04262)

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