近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Hekimi, S. and O'Shea, M. (1987) Identification of precursors of the insect neuropeptide adipokinetic hormone. J. Neurosci. 7(9):2773-2784 Hekimi, S. and O'Shea, M. (1989) Biosynthesis of adipokinetic hormones (AKHs): further characterisation of precursors and identification of novel products of processing. J. Neurosci. 9(3):996-1004. Hekimi, S. and O'Shea, M. (1989) Antisera against AKHs and AKH precursors to study an insect neuroendocrine system. Insect Biochem. 19:79-83. Hekimi, S., Burkhart, W., Moyer, M., Fowler, E. and O'Shea, M. (1989) Dimer structure of neuropeptide precursor established: consequences for processing. Neuron, 2:1363-1368. Hekimi, S. (1990) A neuron-specific antigen in C.elegans allows visualization of the entire nervous system. Neuron, 4:855-865. Hekimi, S., Fischer-Lougheed, J. and O'Shea, M. (1991) Regulation of neuropeptide stoichiometry in neurosecretory cells. J. Neurosci. (10)11:3246-3257. Hosono, R., Hekimi, S., Kamiya, Y., Sassa, T., Murakami, S., Nishiwaki, S., Miwa, J., Taketo, A. and Kodaira, K.-I. (1991) The gene unc-18 encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode C.elegans. J. Neurochem. 58(4):1517-1525. Hekimi, S. and Kershaw D. (1993) Axonal guidance defects in a Caenorhabditis elegans mutant reveal cell-extrinsic determinants of neuronal morphology. J. Neurosci. 13(10):4254-4272. Wong A., Boutis P., and Hekimi S. (1995) Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. Genetics, 139:1247-1259. Barnes T., Kohara Y., Coulson A, and Hekimi S. (1995) Meiotic recombination, non-coding DNA and genomic organization in Caenorhabditis elegans. Genetics, 141: 159-179 Hekimi S., Boutis P., and Lakowski B. (1995) Viable, maternal-effect mutations which affect the development of the nematode Caenorhabditis elegans. Genetics, 141: 1351-1364. Barnes TM, Yin Y, Horvitz HR, Ruvkun G, Hekimi S. (1996) The C.elegans behavioural gene unc-24 encodes a novel bipartite protein similar to both erythrocyte band 7.2 (stomatin) and non-specific lipid transfer protein (nsLTP). J Neurochemistry, 67(1): 46-57. Lakowski B, Hekimi S. (1996) Determination of Life-Span in Caenorhabditis elegans by Four Clock Genes. Science, 272:1010-1013. Ewbank JJ, Barnes TM, Lakowski B, Lussier M, Bussey H, Hekimi S (1997) Structural and Functional Conservation of the C. elegans Clock Gene clk-1. Science, 279: 980-983. Ogura K, Shirakawa M, Barnes T, Hekimi S, Ohshima Y (1997) The UNC-14 protein required for axonal elongation and guidance in Caenorhabditis elegans interacts with the serine/threonine kinase UNC-51. Genes and Development, 11(14): 1801-1810. Barnes T, Hekimi S (1997) The C. elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. J Neurochemistry, 69(6): 2251-2260. Takagi S, Bénard C, Pak J, Livingstone D, Hekimi S (1997) Cellular and axonal migrations are misguided along both body axes in the maternal-effect mau-2 mutants of Caenorhabditis elegans. Development, 124(24): 5115-5126. Lakowski B, Hekimi S (1998) The genetics of caloric restriction in C. elegans. Proceeding of the National Academy of Science of the USA, 22: 13091-13096 Labbé J-C, Hekimi S, Rokeach LA, (1998) The levels of RoRNP-associated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 protein. Genetics, 151: 143-150. Felkai S, Ewbank J, Lemieux J, Labbé J-C, Brown G, Hekimi S (1999) Control of respiration behavior and aging by the physiological clock gene clk-1. EMBO J, 18 (7): 1783-1792. Whitfield CW, Benard C, Barnes T, Hekimi S, Kim SK (1999) Basolateral localization of the C. elegans EGF receptor in epithelial cells by the PDZ protein LIN-10. Molecular Biology of the Cell, 10 (6):2087-100. Labbé J-C, Burgess J, Rokeach L, Hekimi S (2000) ROP-1, an RNA quality control pathway component, affects Caenorhabditis elegans dauer formation. Proceeding of the National Academy of Science of the USA, 97: 13233-38 Miyadera H, Amino H, Hiraishi A , Taka H, Murayama K, Miyoshi H, Sakamoto H, Ishii A, Hekimi S, Kita K (2001) Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans Journal of Biological Chemistry, 276:7713-7716. Jiang N, Levavasseur F, McCright B, Shoubridge EA, Hekimi S (2001) Mouse CLK-1 is imported into mitochondria by an unusual process that requires a leader sequence but no membrane potential. Journal of Biological Chemistry, 276:29218-29225. Lemieux J, Lakowski, Webb A, Barnes T, Meng Y, Hekimi S (2001) Regulation of physiological rates in Caenorhabditis elegans by a tRNA modifying enzyme in the mitochondria. Genetics, 159: 147-157.