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Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets. Wever, C.M., Farrington, D. and Dent, J.A. (2015) The Validation of Nematode-Specific PLoS ONE, 10: e0138804 doi:10.1371/journal.pone.0138804. A dyf-7 haplotype causes sensory neuron defects and is associated with macrocyclic lactone resistance worldwide in the nematode parasite Haemonchus contortus. Urdaneta-Marquez, L., Bae, S.H., Janukavicius, P., Beech, R., Dent, J., Prichard, R. (2014) International journal of Parasitology 44: 1063–1071 Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni. Dufour, V., Beech, R.N., Wever, C., Dent, J.A., Geary, T.G. PLoS Pathology 9(8): e1003586. (2013) doi:10.1371/journal.ppat.1003586 Stoichiometry of the Human Glycine Receptor Revealed by Direct Subunit Counting. Durisic, N., Godin, A.G., Wever, C.M., Heyes, C.D., Lakadamyali, M and Dent, J.A. (2012) Journal of Neuroscience 32: 12915–12920. Nematode parasite genes: what's in a name? Beech, R.N., Wolstenholme, A.J., Neveu, C. and Dent, J.A. (2010) Trends in Parasitology 26: 334-340. Aplysia cys-loop Glutamate-Gated Chloride Channels Reveal Convergent Evolution of Ligand Specificity. Kehoe, J., Buldakova, S., Acher, F., Dent, J.A., Bregestovski, P., and Bradley (2009) J. Journal of Molecular Evolution 69: 125-141. Chapter II: The evolution of pentameric ligand-gated ion channels. In Insect Nicotinic Acetylcholine Receptors. Dent, J.A. (2009) S. Thany, ed., Landes Bioscience, Georgetown TX. Molecular characterization of a pH-gated chloride channel from Sarcoptes scabiei. Mounsey, K.E., Dent, J.A., Holt, D.C. McCarthy, J. Currie, B.J. and Walton, S.F. (2007) Invertebrate Neuroscience 7: 149-156. The serotonin receptor SER-1 (5HT2ce) contributes to the regulation of locomotion in Caenorhabditis elegans. Dernovici, S., Starc, T., Dent, J.A. and Ribeiro, P. (2007) Journal of Neurobiology 67: 189-204. Published Online: 7 Dec 2006 Evidence for a diverse cys-loop ligand-gated ion channel superfamily in early bilateria. Dent, J.A. (2006) Journal of Molecular Evolution 62: 523-535. Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans. De Jong, L., Meng, Y., Dent, J.A. & Hekimi, S.(2004) Genetics 168: 845-854. Genomic organisation of an avermectin receptor subunit from Haemonchus contortus and the expression of its promoter region in Caenorhabditis elegans. Liu, J., Dent, J.A., Beech, R.N. & Prichard, R.K. (2004) Molecular and Biochemical Parasitology 134: 267-274. Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin. Forrester, S.G., Prichard, R.K. Dent, J.A. & Beech, R.N. (2003) Molecular and Biochemical Parasitology 129: 115-121. Regulation of intermuscular electrical coupling by the Caenorhabditis elegans innexin inx-6. Li, S., Dent, J.A. & Roy, R. (2003) Molecular Biology of the Cell 14: 2630-2644. Reversal frequency in C. elegans represents an integrated response to the state of the worm and its environment. Zhao, B., Khare, P., Feldman, L. & Dent, J.A. (2003) Journal of Neuroscience 23: 5319-5328. What can Caenorhabditis elegans tell us about nematocides and parasites? Dent, J.A. (2001) Biotechnology and Bioprocess Engineering 6: 1-6. The genetics of ivermectin resistance in Caenorhabditis elegans. Dent, J.A., Smith, M., Vassilatis, D.K. and Avery, L. (2000) Proc. Nat. Acad. Sci. 97(6): 2674-2679.