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Xia, Yu (Brandon) Associate Professor 收藏 完善纠错
McGill University    Department of Bioengineering
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研究领域

Construction of genome-scale computer models of biomolecular networks with high spatial and temporal resolutions. Use of genome-scale models to probe the biophysical and engineering principles of biological networks. Use of genome-scale models to study the systems biology of diseases Computational Structural Biology. Prediction and analysis of protein structure and function; evolutionary and design principles of proteins Computational Systems Biology. Prediction and analysis of protein networks; evolutionary and design principles of protein networks. Bioinformatics. Development and application of bioinformatics algorithms to analyze biological sequence, structural and functional data.

近期论文

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Structural principles within the human-virus protein-protein interaction network. Franzosa EA, Xia Y. Proc. Natl. Acad. Sci. USA 108: 10538-10543 (2011). Structural determinants of protein evolution are context-sensitive at the residue level. Franzosa EA, Xia Y. Mol. Biol. Evol. 26: 2387-2395 (2009). Relating three-dimensional structures to protein networks provides evolutionary insights. Kim PM, Lu LJ, Xia Y, Gerstein MB. Science 314: 1938-1941 (2006).

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