McKee, Marc D. - McGill University - Department of Anatomy and Cell Biology

研究领域

Mineralized tissues and extracellular matrix biology, pathologic calcification, bone and tooth cell biology, osteopontin, matrix Gla protein.

近期论文

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Boukpessi T, Hoac B, Coyac BR, Leger T, Garcia C, Wicart P, Whyte MP, Glorieux FH, Linglart A, Chaussain C and McKee MD (2017) Osteopontin and the dento-osseous pathobiology of X-linked hypophosphatemia. Bone 95:151-161. Lomashvilli KA, Manning KE, Weitzmann MN, Nelea V, McKee MD, O’Neill WC (2017) Persistence of vascular calcification after reversal of uremia. Amer. J. Pathol. 187:332-338. Jiang W, Pacella MS, Athanasiadou D, Nelea V, Vali H, Hazen RM, Gray JJ and McKee MD. Chiral acidic amino acids induce chiral hierarchical structure in calcium carbonate. Nature Comm. In Press. Chicatun F, Griffanti G, McKee MD, Nazhat S (2017) Collagen/chitosan composite scaffolds for bone and cartilage tissue engineering. In: Biomedical Composites, 2nd Edition). Ed. L. Ambrosio, Woodhead Publishing, Sawston, Cambridge, UK. In Press. Eimar H, Tamimi F, Retrouvey JM, Rauch F, Aubin JE and McKee MD (2016) Craniofacial and dental defects in the Col1a1Jrt/+ mouse model of osteogenesis imperfecta. J. Dent. Res. 95:761-768. Abdallah MN, Eimar H, Bassett DC, Schnabel M, Nelea V, McKee MD, Cerruti M and Tamimi F (2016) Diagenesis-inspired reaction of magnesium ions with surface enamel mineral modifies properties of human teeth. Acta Biomaterialia 37:174-183. Jahnen-Dechent W, Brylka L, Schinke T and McKee MD (2016) Letter to the Editor re: Mattinzoli D et al. FGF23-regulated production of Fetuin-A (AHSG) in osteocytes. Bone 93:223-224. Neves RL, Chiarantin GD, Nascimento FD, Pesquero JB, Nader HB, Tersariol IL, McKee MD, Carmona AK and Barros NMT (2016) Expression and inactivation of osteopontin-degrading PHEX enzyme in squamous cell carcinoma. Intl. J. Biochem. Cell Biol. 77:155-164. Addison WN, Nelea V, Chicatun F, Chien YC, Tran-Khanh N, Buschmann MD, Nazhat SN, Kaartinen MT, Vali H, Tecklenburg MM, Franceschi RT and, McKee MD (2015). Extracellular matrix mineralization in murine MC3T3-E1 osteoblast cultures: An ultrastructural, compositional and comparative analysis with mouse bone. Bone. 71:244-256. Al-Jallad H, Palomo T, Roughley P, Glorieux FH, McKee MD, Moffatt P and Rauch F (2015) The effect of SERPINF1 in-frame mutations in osteogenesis imperfecta type VI. Bone 76:115-120. Komarova SV, Safranek L, Gopalakrishnan J, Ou MJ, McKee MD, Murshed M, Rauch F and Zuhr E (2015) Mathematical model for bone mineralization. Front. Cell Dev. Biol. 3(51):1-11, http://dx.doi.org/10.3389/fcell.2015.00051. Yuan Q, Jiang Y, Zhao X, Sato T, Densmore M, Schüler C, Erben RG, McKee MD and Lanske B (2014) Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice. J. Bone Miner. Res. 29:693-704. Salmon B, Bardet C, Coyac BR, Baroukh B, Naji J, Rowe PS, Opsahl Vital S, Linglart A,McKee MD and Chaussain C (2014) Abnormal osteopontin and matrix extracellular phosphoglycoprotein localization, and odontoblast differentiation, in X-linked hypophosphatemic teeth. Connect. Tissue Res. 55:79-82. Nelea V, Chien YC, Paquette J and McKee MD (2014) Effects of full-length phosphorylated osteopontin and constituent acidic peptides and amino acids on calcite dissolution. Cryst. Growth Des. 14:979-987. Hu J, Hu Y, Lu Y, Smith CE, Lertlam R, Wright JT, Suggs C, McKee MD, Beniash E, Kabir ME and Simmer JP (2014) Enamelin is critical for ameloblast integrity and enamel ultrastructure formation. PLOS ONE 9(3):e89303. Lin S, Zhang Q, Cao Z, Lu Y, Zhang H, Yan K, Liu Y, McKee MD, Qin C, Chen Z and Feng JQ (2014) Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype. J. Biol. Chem. 289:21533-21543. Foster BL, Nagatomo KJ, Tso HW, Tran AB, Nociti FH, Narisawa S, Yadav MC, McKee MD, Millan JL and Somerman MJ (2013) Tooth root dentin mineralization defects in a mouse model of hypophosphatasia. J. Bone Miner. Res. 28:271–282. Barros NMT, Hoac B, Neves RL, Addison WN, Assis DM, Murshed M, Carmona AK and McKee MD (2013) Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatasia. J. Bone Mineral Res. 28:688-699. Khayer Dastjerdi A, Pagano M, Kaartinen MT, McKee MD and Barthelat F (2013) Direct measurements of the cohesive behavior of soft biological interfaces. In: Mechanics of Biological Systems and Materials, Volume 5: Proc. 2012 Annual Conf. on Experimental and Applied Mechanics. Eds. Prorok BC et al. The Society for Experimental Mechanics, Inc., Costa Mesa, CA, USA. pp. 207-215. Mohazab L, Koivisto L, Jiang G, Kytomaki L, Haapasalo M, Owen GR, Wiebe C, Xie Y, Heikinheimo K, Yoshida T, Smith CE, Heino J, Hakkinen L, McKee MD and Larjava H (2013) Critical role for αvβ6 integrin in enamel biomineralization. J. Cell Sci. 126:732-744. Hoac B, Kiffer-Moreira T, Millan JL and McKee MD (2013) Polyphosphates inhibit extracellular matrix mineralization in MC3T3-E1 osteoblast cultures. Bone 53:478-486. Salmon B, Bardet C, Khaddam M, Naji J, Coyac BR, Baroukh B, Letourneur F, Lesieur J, Decup F, Le-Denmat D, Nicoletti A, Poliard A, Rowe PS, Huet E, Opsahl Vital S, Linglart A, McKee MD and Chaussain C (2013) MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia. PLOS ONE 8(2):e56749 Khavandgar Z, Alebrahim S, Eimar H, Tamimi F, McKee MD and Murshed M (2013) Local regulation of tooth mineralization by sphingomyelin phosphodiesterase 3. J. Dent Res. 92:358-364. Coyac BR, Chicatun F, Hoac B, Nelea V, Chaussain C, Nazhat SN and McKee MD (2013) Mineralization of dense collagen hydrogel scaffolds by human pulp cells. J. Dent. Res. 92:648-654. McKee MD, Hoac B, Addison WN, Barros NMT, Millan JL and Chaussain C (2013) Extracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemia. Perio. 2000, 63:102-122.