Zerges, William - Concordia University

研究领域

We are investigating cell biological processes in the chloroplast of Chlamydomonas reinhardtii. This unicellular green alga is a popular model organism for research of chloroplast biogenesis and photosynthesis. We have identified two novel chloroplast compartments with intriguingly similarities to the endoplasmic reticulum and stress granules.

近期论文

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Joerg Nickelsen and William Zerges. (2013) Thylakoid biogenesis has joined the new era of bacterial cell biology. Frontiers in Plant Science. 2013 Nov 13;4:458. Simon, D.F., Domingos, R.F., Hauser C., Hutchins, C.M., Zerges W., K.J Wilkinson. (2013) RNA-Seq analysis of the effects of metal nanoparticle exposure on the transcriptome of Chlamydomonas reinhardtii. Applied Environmental Microbiology 79(16) 4774-85. Bohne, A.-V., Schwarz, C., Schottkowski, M., Lidschreiber, M., Piotrowski, M., Zerges, W. and Nickelsen, J. (2013). Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis. PLoS Biology. 2013 11 (2): 1-18 (Highlighted in Nature Chemical Biology's News &Views April 2013.) B. L. Weis, E. Schleiff, and W. Zerges (2013) Protein targeting to subcellular organelles via mRNA localization. Biochimica et Biophysica Acta- Molecular Cell Research 1833; 260-273. Schottkowski, M, M. Peters, Yu Zhan, O. Rifai, Y. Zhang, and W. Zerges (2012) Biogenic membranes of the chloroplast in Chlamydomonas reinhardtii. Proceedings of the National Academy of Sciences U S A 109(47):19286-19291. Hutchins, C.M, Simon, DF, Zerges, W. and KJ Wilkinson. (2010) Transcriptomic signatures in Chlamydomonas reinhardtii as Cd biomarkers in metal mixtures. Aquatic Toxicology 100(1):120- Uniacke, J. and W. Zerges. 2009. Chloroplast protein targeting involves localized translation in Chlamydomonas. Proceedings of the National Academy of Sciences U S A 106(5):1349-44. Simon DF, Descombes P, Zerges W, Wilkinson KJ. (2008) Global expression profiling of Chlamydomonas reinhardtii exposed to trace levels of free cadmium. Environmental Toxicology and Chemistry. 27(8):1668‐75. Uniacke, J. and W. Zerges (2008) Stress induces the assembly of RNA granules in the chloroplast of Chlamydomonas reinhardtii. Journal of Cell Biology 182(4):641‐6. Uniacke, J. and W. Zerges (2007) "Photosystem II Assembly and Repair Are Differentially Localized in Chlamydomonas." The Plant Cell 19(11): 3640‐54.