个人简介

Education B.S. Chemistry, Seoul National University, Korea, 1975 M.S. Chemistry, Seoul National University, Korea, 1977 Ph.D. Molecular Biology and Biochemistry, princeton university, USA, 1984 Research Experiences Postdoctoral, Molecular Genetics, Beckman National Research Institute of City of Hope, CA, USA, 1986

研究领域

BIO

Current Research Interests The Development of drug delivery system. The Development of gene delivery system.

近期论文

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Reconbinant soluble neprilysin reduces amyoid-beta accumulation and improves memory impairment in Alzheimer's disease mice , Min Hee Park, Jong Kil Lee, Sunghyun Choi, Junseing Ahn, Hee Kyung Jin, Jong-Sang Park, Jae-sung Bae , Brain Reserch. 1529(1), pp.113-124 (2013) Comparison of the Neointima Inhibition Between Paclitaxel- and Sirolimus-Eluting Expanded Polytetrafluoroethylene Hemodialysis Grafts in a Porcine Model , Inso Baek, AJin Cho, Jinsun Hwang, Heasun Kim, Jong-Sang Park, Dae Joong Kim , B. Kor. Chem. Soc. 34(6), pp.1663-1667 (2013) Hsp27 Reduces Phosphorylated Tau and Prevents Cell Death in the Human Neuroblstoma Cell Line SH-SY5Y , Junseong Ahn, Hyeseon Kim, Jong-Sang Park , B. Kor. Chem. Soc. 34(5), pp.1503-1507 (2013) Stimulation of Phospholipase D in HepG2 cells After Transfection Using Cationic Liposomes , Sang Yoon Lee, Yan Lee, Joon Sig Choi, Jong-Sang Park, Myung-Un Choi , B. Kor. Chem. Soc. 34(3), pp.931-935 (2013) Arginine modified PAMAM dendrimer for interferon beta gene delivery to malignant glioma , Cheng Zhe Bai, Sunghyun Choi, Kihoon Nam, Sunghie An, Yan Lee, Jong-Sang Park , Int J Pham. 445, pp.79-87 (2013) Nonviral Gene Therapy in vivo with PAM-RG4/apoptin as a potntial brain Tumor Therapeutic , Sunghie An, Kihoon Nam, Sunghyun Choi, Cheng Z Bai, Yan Lee, Jong-Sang Park , Int J Nanomed. 8(1), pp.821-834 (2013) PAMAM Dendrimers Conjugated with L-Arginine and γ-Aminobutyric Acid as Novel Polymeric Gene Delivery Carriers , Sang Jae Son, Gwang Sig Yu, Yun Hui Choe, Youn-Joong Kim, Eunji Lee, Jong-Sang Park, Joon Sig Choi , B. Kor. Chem. Soc. 34(2), pp.579-584 (2013) Arginine Modified PAMAM Dendrimer for Interferon Beta Gene Delivery to Malignant Glioma , Cheng Zhe Bai, Sunghyun Choi, Kihoon Nam, Songhie An, Jong-Sang Park , Int. J. Pharm. 445(1-2), pp.79-87 (2013) Nonviral Gene Therapy in vivo with PAM-RG4/apoptin as a Potential Brain Tumor Therapeutic , Songhie An, Kihoon Nam, Sunghyun Choi, Cheng Z Bai, Yan Lee, Jong-Sang Park , Int. J. Nanomed. 8(1), pp.821-834 (2013) Development of SS-AG20-loaded Polymeric Microparticles by Oil-in-Water (o/w) Emulsion Solvent Evaporation and Spray Drying Methods for Sustained Drug Delivery , Eunjung Choi, Cheng Zhe Bai, Areum Hong, and Jong-Sang Park , Bull. Korean Chem. Soc., 33(10), pp.3208-3212 (2012) Synthesis, Characterization and Application of Dendritic Lipids for Gene Delivery , Hyung-Suk Jang, Yan Lee, Tae-Il Kim, Jong-Sang Park, and Joon Sig Choi , Bull. Korean Chem. Soc. , 33(4), pp.1353-11356 (2012) Formation of Polyion Complex Micelles with Tunable Isoelectric Points Based on Zwitterionic Block Copolymers , Geun-woo Jin, Heejin Kim, Ji-Hun Seo, Jiyeon Ham, Jong-Sang Park, Yan Lee , Macromol. Res. , 20(12), pp.1249-1256 (2012) Elevation of Transfection Efficiency by Conjugation of Poly(amindoamine)-diethylenetriamine (PAM-DET) with Dexamethasone , Yunseong Jeong, Jihye Park, Geun-woo Jin, and Jong-Sang Park , Bull. Korean Chem. Soc. , 33(11), pp.3849-3852 (2012) Combination of Epstein-Barr Virus-Based Plasmid and Nonviral Polymeric Vectors for Enhanced and Prolonged Gene Expression , Hye Choi, Key Sun Park, Seon Joo Bae, Su Jeong Song, Kyoon Eon Kim, Jong-Sang Park and Joon Sig Choi , Bull. Korean Chem. Soc. , 33(11), pp.3676-3680 (2012) Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain , Il-Doo Kim, Joo-Hyun Shin, Seung-Woo Kim, Sunghyun Choi, Junseong Ahn, Pyung-Lim Han, Jong-Sang Park and Ja-Kyeong Lee , Mol Ther , 20(4), pp.829-839 (2012) Effective healing of diabetic skin wounds by using nonviral gene therapy based on minicircle vascular endothelial growth factor DNA and a cationic dendrimer , Min J. Kwon, Songhie An, Sunghyun Choi, Kihoon Nam, Hye S. Jung, Chang S. Yoon, Jung H. Ko, Hye J. Jun, Tae K. Kim, Soo J. Jung, Jeong H. Park, Yan Lee, Jong-Sang Park , J Gene Med , 14, pp.272-278 (2012) Paclitaxel coating of the luminal surface of hemodialysis grafts with effective suppression of neointimal hyperplasia , Baek I, Zhe Bai C, Hwang J, Nam HY, Park JS, Kim DJ , J Vasc Surg , 55(3), pp.806-U502 (2012) Topically Administered Risedronate Shows Powerful Anti-osteoporosis Effect in Ovariectomized Mouse Model , So Hee Nam, Jae-Hwan Jeong, Xiangguo Che, Kyung-Eun Lim, Hyemi Nam, Jong-Sang Park, Je-Yong Choi , Bone , 50(1), pp.149-155 (2012) Suppression of neointimal hyperplasia by sirolimus-eluting expanded polytetrafluoroethylene (ePTFE) haemodialysis grafts in comparison with paclitaxel-coated grafts , Baek I, Bai CZ, Hwang J, Park J, Park JS, Kim DJ , Nephrol Dial Transplant , Nov (0), pp.1-8 (2011) The Natural Product NI-07, Is Effective Against Breast Cancer Cells While Showing No Cytotoxicity to Normal Cells , Lauren S. Gollahon, Yunseong Jeong, Velvetlee Finckbone, Kyungwoo Lee, Jong-Sang Park , The Open Breast Cancer Journal , 3, pp.31-44 (2011)