个人简介
Education
B. S. Chemistry, Seoul National University, Korea, 1999
M. S. Chemistry, Seoul National University, Korea, 2001
Ph. D. Chemistry, Seoul National University, Korea, 2005
Research Experiences
Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-Present.
Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.
近期论文
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Unlocking the pH-Responsive Degradability of Fumaramic Acid Derivatives Using Photoisomerization. Wonmin Choi, Sunyoung Kang, Yeongbong Mok, Euddeum Park, Youngjun Song, So Jung Choi, Yan Lee, Chemistry-A European Journal 20(48), pp.15715-15718 (2014)
Apoptosis Inducing, Conformationally Constrained, Dimeric Peptide Analogs of KLA with Submicromolar Cell Penetrating Abilities. Soonsil Hyun, Seonju Lee, Seoyeon Kim, Sangmok Jang, Jaehoon Yu, Yan Lee, Biomacromolecules 15(10), pp.3746-3752 (2014)
Alleviation of Capsular Formations on Silicone Implants in Rats using Biomembrane-mimicking Coatings. Ji Ung Park, Jiyeon Ham, Sukwha Kim, Ji-Hun Seo, Sang-Hyon Kim, Seonju Lee, Hye Jeong Min, Sunghyun Choi, Ra Mi Choi, Heejin Kim, Sohee Oh, Ji An Hur, Tae Hyun Choi, Yan Lee, Acta Biomaterialia 10(10), pp.4217-4225 (2014)
Cell-Penetrating, Dimeric α-Helical Peptides: Nanomolar Inhibitors of HIV-1 Transcription. Sangmok Jang, Soonsil Hyun, Seoyeon Kim, Seonju Lee, Im-Soon Lee, Masanori Baba, Yan Lee, Jaehoon Yu, Angewandte Chemie-International Edition 53(38), pp.10086-10089 (2014)
A Medusa-like β-cyclodextrin with 1-methyl-2-(2'-carboxyethyl) Maleic Anhydrides, a Potential Carrier for pH-sensitive Drug Delivery. Sunyoung Kang, Euddeum Park, Youngeun Kim, Seonju Lee, Jiwoong Kwon, Hyungdo Cho, Yan Lee, Journal of Drug Targeting 22(7), pp.658-668 (2014)
Comparison of pH-Sensitive Degradability of Maleic Acid Amide Derivatives. Sunyoung Kang, Youngeun Kim, Youngjun Song, Jin Uk Choi, Euddeum Park, Wonmin Choi, Jeongseon Park, Yan Lee, Bioorganic & Medicinal Chemistry Letters 24(10), pp.2364-2367 (2014)
Lower Critical Solution Temperature (LCST) Phase Separation of Glycol Ethers for Forward Osmotic Control. Daichi Nakayama, Yeongbong Mok, Minwoo Noh, Jeongseon Park, Sunyoung Kang, Yan Lee, Physical Chemistry Chemical Physics 16(11), pp.5319-5325 (2014)
Synthesis of Biomembrane-mimic Polymers with Various Phospholipid Head Groups. Heejin Kim, Wonmin Choi, Seonju Lee, Sooyeol Kim, Jiyeon Ham, Ji-Hun Seo, Sangmok Jang, Yan Lee, Polymer 55(2), pp.517-524 (2014)
Circulatory Osmotic Desalination Driven by a Mild Temperature Gradient Based on Lower Critical Solution Temperature (LCST) Phase Transition Materials. Yeongbong Mok, Daichi Nakayama, Minwoo Noh, Sangmok Jang, Taeho Kim, Yan Lee, Physical Chemistry Chemical Physics 15(44), pp.19510-19517 (2013)
Introduction of pH-Sensitive Upper Critical Solution Temperature (UCST) Properties into Branched Polyethylenimine. Minwoo Noh, Yeongbong Mok, Daichi Nakayama, Sangmok Jang, Seonju Lee, Taeho Kim, Yan Lee, Polymer 54(20), pp.5338-5344 (2013)
Preparation of Non-Aggregated Fluorescent Nanodiamonds (FNDs) by Non-Covalent Coating with a Block Copolymer and Proteins for Enhancement of Intracellular Uptake. Jong Woo Lee, Seonju Lee, Sangmok Jang, Kyu Young Han, Younggyu Kim, Jaekyung Hyun, Seong Keun Kim, Yan Lee, Molecular BioSystems 9(5), pp.1004-1011 (2013)
Stimulation of Phospholipase D in HepG2 Cells After Transfection Using Cationic Liposomes. Sang Yoon Lee, Yan Lee, Joon Sig Choi, Jong-Sang Park, Myung-Un Choi, Bulletin of The Korean Chemical Society 34(3), pp.931-935 (2013)
Nonviral Gene Therapy in vivo with PAM-RG4/apoptin as a Potential Brain Tumor Therapeutic. Songhie An, Kihoon Nam, Sunghyun Choi, Cheng Z Bai, Yan Lee, Jong-Sang Park, International Journal of Nanomedicine 8(1), pp.821-834 (2013)
Formation of Polyion Complex Micelles with Tunable Isoelectric Points Based on Zwitterionic Block Copolymers. Geun-woo Jin, Heejin Kim, Ji-Hun Seo, Jiyeon Ham, Jong-Sang Park, Yan Lee, Macromolecular Research 20(12), pp.1249-1256 (2012)
Preparation of pH-sensitive CaP Nanoparticles Coated with a Phosphate-based Block Copolymer for Efficient Gene Delivery. Sangmok Jang, Seonju Lee, Heejin Kim, Jiyeon Ham, Ji-Hun Seo, Yeongbong Mok, Minwoo Noh, Yan Lee, Polymer 53(21), pp.4678-4685 (2012)
Novel Lower Critical Solution Temperature Phase Transition Materials Effectively Control Osmosis by Mild Temperature Changes. Minwoo Noh, Yeongbong Mok, Seonju Lee, Heejin Kim, So Hyun Lee, Geun-woo Jin, Ji-Hun Seo, Heebeom Koo, Tae Ha Park, Yan Lee, Chemical Communications 48(32), pp.3845-3847 (2012)
Synthesis, Characterization and Application of Dendritic Lipids for Gene Delivery. Hyung-Suk Jang, Yan Lee, Tae-Il Kim, Jong-Sang Park, Joon Sig Choi, Bulletin of The Korean Chemical Society 33(4), pp.1353-1356 (2012)
Effective Healing of Diabetic Skin Wounds by Using Nonviral Gene Therapy Based on Minicircle Vascular Endothelial Growth Factor DNA and a Cationic Dendrimer. Min J. Kwon, Songhie An, Sunghyun Choi, Kihoon Nam, Hye S. Jung, Chang S. Yoon, Jung H. Ko, Hye J. Jun, Tae K. Kim, Soo J. Jung, Jeong H. Park, Yan Lee, Jong-Sang Park, Journal of Gene Medicine 14(4), pp.272-278 (2012)
Delivery of Nucleic Acid Drugs. Yan Lee, Kazunori Kataoka, Advances in Polymer Science 249(), pp.95-134 (2012)
Enhanced Endosomal Escape of siRNA-incorporating Hybrid Nanoparticles from Calcium Phosphate and PEG-block Charge-conversional Polymer for Efficient gene Knockdown with Negligible Cytotoxicity. Frederico Pittella, Mingzhen Zhang, Yan Lee, Hyun J. Kim, Theofilus Tockary, Kensuke Osada, Takehiko Ishii, Kanjiro Miyata, Nobuhiro Nishiyama, Kazunori Kataoka, Biomaterials 32(11), pp.3106-3114 (2011)
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