Jha, Mukund - Nipissing University - Department of Biology and Chemistry

个人简介

BSc, University of Delhi; MSc, University of Delhi; PhD, University of Saskatchewan

研究领域

Chemical Synthesis Green Chemistry Medicinal Chemistry Microbiology Enzymology

近期论文

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Mukund Jha*, Oro Enaohwo, Stephanie Guy. Yttrium triflate-catalyzed efficient chemoselective S-benzylation of indoline-2-thiones using benzyl alcohols. Tetrahedron Letters, 2011, 52, 684-687. Mukund Jha*, Ting-Yi Chou, Brian Blunt. General synthesis of mono-, di-, and tri-acetylated indoles from indolin-2-ones. Tetrahedron, 2011, 67, 982-989. Mukund Jha*, Oro Enaohwo, Ashley Marcellus. Chemoselective S-benzylation of indoline-2-thiones using benzyl alcohols. Tetrahedron Letters, 2009, 50, 7184-7187. (Highlighted in ChemInform) Mukund Jha*, Brian Blunt. Highly efficient one-pot C-, N-, O- acylation of indolin-2-one analogs. Tetrahedron Letters, 2009, 50, 6044-6047. (Highlighted in ChemInform) Susheel J. Nara, Mukund Jha, Johan Brinkhorst, Tony J. Zemneck, Derek A. Pratt. A simple Cu-catalyzed coupling approach to substituted 3-pyridinols and 5-pyrimidinols. Journal of Organic Chemistry, 2008, 73, 9326-9333. (Highlighted in ChemInform) M. Soledade C. Pedras, Zoran Minic, Mukund Jha. Purification, functional characterization and inhibition of Brassinin Oxidase, a fungal detoxifying enzyme to overcome plant defenses. FEBS Journal, 2008, 275, 3691-3705. Mukund Jha, Derek A. Pratt. Kinetic solvent effects on peroxyl radical reactions. Chemical Communications, 2008, 1252-1254. M. Soledade C. Pedras, Mukund Jha, Zoran Minic, Oladapo G. Okeola. Isosteric probes provide structural requirements for detoxification of the phytoalexin brassinin by the fungal pathogen Leptosphaeria maculans. Bioorganic and Medicinal Chemistry, 2007, 15, 6054-6061. M. Soledade C. Pedras, Ravi S. Gadagi, Mukund Jha, Vijay K. S. Mamillapalle. Detoxification of the phytoalexin brassinin by isolates of Leptosphaeria maculans involves an inducible hydrolase. Phytochemistry, 2007, 68, 1572-1578. M. Soledade C. Pedras, Adewale M. Adio, Mojmir Suchy, Denis P. O. Okinyo, Qing-An Zheng, Mukund Jha, Mohammed G. Sarwar. Detection, characterization and identification of crucifer phytoalexins using high-performance liquid chromatography diode array and electrospray ionization tandem mass spectrometry analyses. Journal of Chromatography A, 2006, 1133, 171-183. M. Soledade C. Pedras, Mukund Jha. Towards the control of Leptosphaeria maculans: design, synthesis, biological activity and metabolism of potential inhibitors of detoxification of the crucifer phytoalexin brassinin. Bioorganic and Medicinal Chemistry, 2006, 14, 4958-4979. M. Soledade C. Pedras, Mukund Jha, Oladapo G. Okeola. Camalexin induces detoxification of the phytoalexin brassinin in the plant pathogen Leptosphaeria maculans. Phytochemistry, 2005, 66, 2609-2616. M. Soledade C. Pedras, Mukund Jha. Concise syntheses of the cruciferous phytoalexins brassilexin, sinalexin, wasalexins and analogs: Expanding the scope of the Vilsmeier formylation. Journal of Organic Chemistry, 2005, 70, 1828-1834. (Highlighted in ChemInform). M. Soledade C. Pedras, Mukund Jha, Pearson W. K. Ahiahonu. The synthesis and biosynthesis of phytoalexins produced by cruciferous plants. Current Organic Chemistry, 2003, 7, 1635-1647