Law, David - Lakehead University - Department of Biology

研究领域

Molecular aquatic toxicology; effects of industrial effluents on fish reproduction; plant biochemistry, molecular biology, and biotechnology; molecular responses of plants to developmental progression; epigenetics, gene expression, proteomics and metabolism of specific plant cell types; molecular function of subunits in multimeric proteins.

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Werner, J., Ouellet, J.D., Cheng, C.S., Ju, Y.-J., and Law, R.D. (2010). Pulp and paper mill effluents induce distinct gene expression changes linked to androgenic and estrogenic responses in the fathead minnow (Pimephales promelas). Environ. Toxicol. Chem. 29: 430-439. DeCarlo, C.A., Escott, N.G., Werner, J., Robinson, K., Lambert, P.F., Law, R.D., and Zehbe, I. (2008). Gene expression analysis of interferon kappa in laser capture microdissected cervical epithelium. Anal. Biochem. 381: 59-66. Law, R.D., Russell, D.A., Thompson, L.C., Schroeder, S.C., Middle, C.M., Tremaine, M.T., Jury, T.P., Delannay, X., and Slater, S.C. (2006). Biochemical limitations to high-level expression of humanized monoclonal antibodies in transgenic maize seed endosperm. Biochim. Biophys. Acta (General Subjects) 1760: 1434-1444. Law, R.D., and Suttle, J.C. (2005). Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions. Plant Physiol. Biochem. 43(6): 527-534. Law, R.D., and Suttle, J.C. (2004). Changes in histone H3 and H4 multiacetylation during natural and forced dormancy break in potato tubers. Physiol. Plant. 120: 642-649. Law, R.D., and Suttle, J.C. (2003). Transient decreases in methylation at 5'-CCGG-3' sequences in potato (Solanum tuberosum L.) meristem DNA during progression of tubers through dormancy precede the resumption of sprout growth. Plant Mol. Biol. 51: 437-447.