Zhanel, George - University of Manitoba - Department of Medical Microbiology and Infectious Diseases

个人简介

Professor, Departmental of Medical Microbiology, University of Manitoba (first appointed Assistant Professor in 1987) Director, Canadian Antimicrobial Resistance Alliance (CARA, http://www.can-r.ca/) Degrees: Ph.D. Medical Microbiology (Manitoba, 1994), Doctor of Pharmacy (Minnesota, 1986)

研究领域

Antibiotic resistant infections including prevalence/epidemiology, cellular and molecular resistance mechanisms, rapid diagnostics, treatment and prevention. Discovery/development of agents used to prevent and/or treat infectious diseases.

近期论文

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Adam HJ, Karlowsky JA, Nichol K, Gilmour MW, Hoban DJ, Embree J and Zhanel GG. Baseline epidemiology ofStreptococcus pneumoniae serotypes in Canada prior to the introduction of the 13-valent pneumococcal vaccine. Microbial Drug Resistance 2012;18(2):176-182. Zhanel GG, Lawson CD, Zelenitsky S, Findlay B, Schweizer F, Adam H, Walkty A, Rubinstein E, Gin AS, Hoban DJ, Lynch JP and Karlowsky JA. Comparison of the next generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin. Expert Reviews in Antiinfective Therapy 2012;10(4):459-473. Zhanel GG, Rossnagel E, Nichol K, Cox, L, Karlowsky JA, Zelenitsky S, Noreddin AM and Hoban DJ. Ceftaroline pharmacodynamic activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus (MRSA), heteroresistant (h) vancomycin-intermediate Staphylococcus aureus (hVISA), VISA and vancomycin-resistant Staphylococcus aureus (VRSA) using an in vitro model. Journal of Antimicrobial Chemotherapy 2011;66(6):1301-1305. Bera S, Zhanel GG and Schweizer F. Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles: Polyol-modified neomycin B, kanamycin A, amikacin and neamine based amphiphiles with potent broad spectrum antibacterial activity. Journal of Medicinal Chemistry 2010;53(9):3626-3631. Zhanel GG, DeCorby M, Adam H, Lagace-Wiens P, Nichol KA, Wierzbowski A, Baudry PJ, Tailor F, Karlowsky JA, Walkty A, Schweizer F, McCracken M, Mulvey MR, Johnson J, The Canadian Antimicrobial Resistance Alliance (CARA) and Hoban DJ. Prevalence of antimicrobial resistant pathogens in Canadian hospitals: Results of the Canadian ward surveillance study (CANWARD 2008). Antimicrobial Agents and Chemotherapy 2010;54(11):4684-4693.