个人简介
Chief, Bioinformatics, National Microbiology Laboratory - Public Health Agency of Canada
Adjunct Professor, Departments of Medical Microbiology, Computer Science and Faculty of Pharmacy, University of Manitoba.
Visiting Professor, Centre for Bioinformatics and Biotechnology, University of Nairobi, Nairobi, Kenya
Degrees: Ph.D (Alberta, 2003), B.Sc (Alberta, 1988)
研究领域
Microbial bioinformatics including metagenomics, molecular diagnostics, computational genomics, and pathogenomics
近期论文
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Petkau A, Stuart-Edwards M, Stothard P, and Van Domselaar G (2010) Prokaryotic Genome Visualization with GView. Bioinformatics (submitted).
Gravel C, Li C, Wang J, Hashem A, Jaentschke B, Xu XW, Lorbetski B, Gingras G, Aubin Y, Van Domselaar G, Girard M, He R , Li X. (2010) Qualitative and quantitative analyses of virtually all subtypes of influenza A and B viral neuraminidases using antibodies targeting universally conserved sequences. Vaccine (in press).
Gilmour MW, Tyler S, Graham M, Van Domselaar G, Kent H, Yakel K, Larios O, Allen V, Lee B, and Nadon C (2010) High-Throughput Genome Sequencing of Two Listeria monocytogenes Clinical Isolates During a Large Foodborne Outbreak . BMC Genomics , 11 :120.
Golding GR, Bryden L, Levett PN, McDonald RR, Wong A, Wylie J, Graham M, Tyler S, Van Domselaar G, Simor AE, Gravel D, and Mulvey MR. (2010) Molecular characterization of “live-stock” associated ST398 methicillin-resistant Staphylococcus aureus isolated from humans, Canada. EID, 16:587-94.
Hashe AM, Flaman AS, Farnsworth A, Brown EG, He R, Van Domselaar G and Li X (2009) Aurintricarboxylic Acid is a potent inhibitor of Influenza A and B virus neuraminidases. PLoS ONE , 4:e8350.
Li C, Jaentschke B, Song Y, Wang J,Cyr TD, Van Domselaar G, He R, Li X (2009) A simple slot blot for the detection of virtually all subtypes of the influenza A viral hemagglutinins using universal antibodies targeting the fusion peptide. Nature Protocols 5:14-19.
Chiang S, Burch T, Van Domselaar G, Radziwon A, Dick K, Brusnyk C, Cutts T, Cao X, Li X and He R (2009) The Interaction between T:G Mismatch Repair Enzyme Thymine DNA Glycosylase and Nuclear Receptor Coactivator 3 is Important for the Transcriptional Activation of Nuclear Hormone Receptors. Biochemistry . Mol Cell Biochem , 33 :221-232
Kropinski AM, Borodovsky M, Carver TJ, Cerde?o-Tárraga AM, Darling A, Lomsadze A, Mahadevan P, Stothard P, Seto D, Van Domselaar G, and Wishart DS. (2009) “In silico analysis of bacteriophage genomic DNA ” in Methods in Molecular Biology, vol 132: Bacteriophages (Martha R.J. Clokie and Andrew M. Kropinski, eds.) Humana Press Inc., Totowa, NJ
Chun S, Li C, Van Domselaar G, Wang J, Farnsworth A , Cui X, Rode H, . Cyr TD, He R. and Li X. (2008) Universal antibodies and their applications to the quantitative determination of virtually all subtypes of the influenza A viral hemagglutinins. Vaccine 26:6068-6076.
Liang BB, Luo M, Ball TB, Jones SJM , Yao X, Van Domselaar GH, Cheang M, and Plummer FA (2008) Systematic Analysis of Host Immunological Pressure on the Envelope Gene of Human immunodeficiency virus Type 1 by an Immunological Bioinformatics Approach. Current HIV Research 6:370-379.