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研究领域

multidrug resistance in Gram-negative bacteria, Resistance-Nodulation-Division efflux pumps, Acinetobacter, Pseudomonas, pathogenicity and virulence, bacterial stress response, genomics and transcriptomics

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Fernando, D., Xu, W., Loewen, P. C., Zhanel, G. G., and Kumar, A. (2014) Triclosan can select for AdeIJK overexpressing mutant of Acinetobacter baumannii ATCC17978 that displays reduced susceptibility to multiple antibiotics. Antimicrobial Agents and Chemotherapy, 58:6424-6431. Loewen, P. C., Alsaadi, Y., Fernando, D., Kumar, A. (2014) Genome sequence of a tigecycline-resistant clinical isolate of Acinetobacter baumannii strain AB031 obtained from a bloodstream infection. Genome Announcements, 2:pii: e01036-14. Loewen, P. C., Alsaadi, Y., Fernando, D., Kumar, A. (2014) Genome sequence of an extremely drug-resistant clinical isolate of Acinetobacter baumannii strain AB030. Genome Announcements, 2:pii: e01035-14. Moya-Torres, A., Mulvey, M. R., Kumar, A., Oresnik, I. J., and Brassinga, A. K. C. (2014) The lack of OmpF, but not OmpC, contributes to increased antibiotic resistance in Serratia marcescens. Microbiology, 160:1882-1892. Bazyleu, A and Kumar, A. (2014) Incubation temperature, osmolarity, and salicylate affect the expression of Resistance-Nodulation-Division efflux pumps and outer membrane porins in Acinetobacter baumannii ATCC19606T. FEMS Microbiology Letters, 357(2):136-143. Tilley, D., Law, R., Warren, S., Samis, J., and Kumar, A. (2014) CpaA a novel protease from Acinetobacter baumannii clinical isolates deregulates blood coagulation. FEMS Microbiology Letters, 356: 53-61. (Editor's choice for the issue) Fernando, D. and Kumar, A. (2013) Resistance-nodulation-division multidrug efflux pumps in Gram-negative bacteria: role in virulence. Antibiotics, 2: 163-181. Fernando, D., Zhanel, G. G., and Kumar, A. (2013) Antibiotic resistance and expression of resistance-nodulation-division pumps and outer membrane porins in Acinetobacter spp isolated from Canadian hospitals. Canadian Journal of Infectious Diseases and Medical Microbiology, 24: 17-21. Fernando, D. and Kumar, A. (2012) Growth phase-dependent expression of RND efflux pump- and outermembrane porin-encoding genes in Acinetobacter baumannii ATCC19606. Journal of Antimicrobial Chemotherapy, 67:569-572.

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