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研究领域

Molecular characterization of hepatitis B virus (HBV): investigation of HBV genotypes, drug-resistant and immune-escape mutants; molecular epidemiology of HBV infection; investigation of occult HBV; HBV molecular evolution; investigation of HBV in indigenous populations of the circumpolar Arctic.

近期论文

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Willmore, J., Ellis, E., Etches, V., Labrecque, L., Osiowy, C., Andonov, A., McDermaid, C., Majury, A., Achonu, C., Maher, M., MacLean, B., Levy, I. (2014) Public health response to a large-scale endoscopy infection control lapse in a non-hospital clinic. Canadian Journal of Infectious Disease and Medical Microbiology (In press; November 2014.) Coffin, C.S., Osiowy, C., Gao, S., Nishikawa, S., van der Meer, F., van Marle, G. (2014) Hepatitis B Virus (HBV) Variants Fluctuate in Paired Plasma and Peripheral Blood Mononuclear Cells Among Patient Cohorts During Different Chronic Hepatitis B (CHB) Disease Phases. Journal of Viral Hepatitis (ahead of print September 2014 doi: 10.1111/jvh.12308). Coffin, C.S., Mulrooney-Cousins, P.M., Osiowy, C., van der Meer, F., Nishikawa, S., Michalak, T.I., van Marle, G., and Gill, M.J. (2014) Virological characteristics of occult hepatitis B virus in a North American cohort of human immunodeficiency virus type 1-positive patients on dual active anti-HBV/HIV therapy. Journal of Clinical Virology 60(4):347-53. Minuk, G.Y., Huynh, C., Uhanova, J., and Osiowy, C. (2014) Establishing diagnostic criteria for occult hepatitis B virus infections in community based populations. Journal of Medical Virology 86(1):156-161. Osiowy, C., Simons, B., and Rempel, J. (2013) Distribution of viral hepatitis in indigenous populations of North America and the circumpolar Arctic. Antiviral Therapy 18(3 Pt B):467-473. Minuk, G.Y., MacRury, S., Uhanova, J., Caouette, S., Coleman, N., Cummings, K., Larke, B., Vardy, L., Huynh, C., and Osiowy, C. (2013) A paucity of liver disease in Canadian Inuit with chronic hepatitis B virus, subgenotype B6 infection. Journal of Viral Hepatitis 20:890-896. Andonov, A., Kadkhoda, K., Osiowy, C., and Kaita, K. (2013) Pre-treatment resistance to hepatitis C virus protease inhibitors boceprevir/telaprevir in HCV subgenotype 1a infected patients from Manitoba, Canada. Canadian Journal of Gastroenterology 27(7):414-416. Kowalec, K., Minuk, G.Y., B?rresen, M., Koch, A., McMahon, B., Simons, B., and Osiowy, C. (2013) Genetic diversity of hepatitis B virus genotypes B6, D and F among circumpolar indigenous individuals with various clinical outcomes. Journal of Viral Hepatitis 20(2):122-130.

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