Li, Yan - University of Manitoba - Department of Medical Microbiology and Infectious Diseases

研究领域

Diagnosis, surveillance and molecular epidemiology of influenza and other respiratory viruses including new emerging respiratory pathogens

近期论文

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Skowronski DM, De Serres G, Dickinson J, Petric M, Mak A, Fonseca K, Kwint TL, Chan T, Bastien N, Charest H, and Li Y.(2009). Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006-2007. J Infect Dis. 199: 168-179. Yan KX, Tan WJ, Wang HJ, Wang Y, Zhang XM, Li Y, and Ruan L. (2009). SARS-CoV spike protein expressed in vaccinia virus TianTan strain: secreted SQ protein induced robust neutralization antibody in mice. Viral Immunology. 22: 57-65. Patel A, Tran K, Gray M, Li Y, Ao Z, Yao X, Kobasa D, and Kobinger G. (2009). Evaulation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses. Vaccine. 27: 3083-3089. Bastien N, Burton L, Bontovics E, Winter AL, McNab B,Tipples G, and Li Y. (2009). Parotitis in a child infected with triple reassortant influenza A virus in Canada in 2007. J. Clin. Microbiol.47: 1896-1898. Luo L, Sabara M, and Li Y. (2009). Analysis of antigenic cross-reactivity between subgroup C avian penumovirus (APV) and human metapneumovirus (hMPV) by using recombinant fusion (F) proteins. Transboun Emerg Dis. 56: 303-310. Culter J, Schleihaul E, Hatchette T, Billard B, Waston-Creed G, Davidson R, Li Y, and Sarwal S. (2009). The first case of human to human transmission of A/H1N1 human swine influenza in Canada. CMAJ. 181: 159-163. Zhao L, Qian Y, Zhu R, Deng J, Wang F, Dong H, Sun Y, and Li Y. (2009). Human bocavirus infections are common in Beijing population indicated by sero-antibody prevalence analysis. Chin Med J. 122 (11): 1289-1292. Hatchette TF, Bastien N, Berry J, Booth TF, Chernesky M, Couillard M, Drews S, Ebsworth A, Fearon M, Fonseca K, Fox J, Gagnon JN, Guercio S, Horsman G, Jorowski C, Kuschak T, Li Y, Majury A, Petric M, Ratnam S, Smieja M, Van Caeseele P; Pandemic Influenza Laboratory Preparedness Network (2009). The limitations of point of care testing for pandemic influenza: what clinicians and public health professionals need to know. Can J Public Health. 100: 204-207. Zhao L, Qian Y, Ding Y, Zhu R, Deng J, Wang F, Sun Y, and Li Y. (2009). The expression of the capsid protein VP2 from human bocavirus identified in Beijing and the formation of virus-like particles (VLPs) in insect cells. Chin J. Virol. 25 (5): 332-338. LeBlanc J, Li Y, Bastien N, Forward, K, Davidson R, and Hatchette T. (2009). Switching gears for a pandemic: validation of a duplex RT-PCR for simultaneous detection and confirmation of pandemic influenza A (H1N1).J. Clin. Microbiol.3805-3813. Papenburg J, Karatzios C, Li Y, Bastien N, Semret M, and Moore D. (2009). A near-fatal infection with oseltamivir-resistant influenza A in a previously healthyu child: case report. Can J Infect Dis Med Microbiol. 20: e173-e176. Luo L, Hose K, Liu L, Sabara M, and Li Y. (2010). Characterization of the biosynthesis and cell surface expression of avian metapneumovirus attachment glycoprotein. Virus Research. 189-194. Weingartl HM, Berhane Y, Neufeld JKehler H, Emburr-Hyatt C, Hooper-McGerrv K, Kasloff S, Dalman D, Bystrom J, Alexandersen S, Li Y, and Pasick J. (2010). Genetic and pathobiological characterization of pandemic H1N1 2009 viruses from a naturally infected swine herd. J. Virol. 84: 2245-2256. Bastien N, Antonishyn NA, Brandt K, Wong CE, Chokani K, Vegh N, Horsman GB, Tyler S, Graham M, Plummer F, Levett PN, and Li Y (2010). Human infection with a triple-reassortant swine influenza A (H1N1) containing HA and NA genes of seasonal influenza. J Infect Dis. 201: 1178-1182. De Serres G, Rouleau I, Hamelin M, Quach C, Skowronski DM, Flamand L, Boulianne N, Li Y, Carbonneau J, Bourgault AM, Couillard M, Charest H, Boivin G (2010). Contagious period for pandemic (H1N1) 2009.Emerg Infect Dis.16: 783-788. Skowronski DM, De Serres G, Crowcroft N, Janjua NZ, , Boulianne N, Hottes T, Rosella LC, Dickinson J, Gilca R, Sethi P, Ouhoummane N, Willison DJ, Rouleau I, Petric M, Fonseca K, Drews SJ, Rebbapragada A, Charest H, Kwindt TL, Hamelin ME, Boivin G, Gardy JL, Li Y, Kwindt TL, Patrick DM, Brunham RC; Canadian SAVOIR Team (2010). Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during spring-summer 2009: four observational studies from Canada. PLoS Medicine. Apr 6;7(4): e1000258. Keynan Y, Card CM, Ball BT, Li Y, Plummer FA, and Fowke KR. (2010). Cellular immune responses to recurring influenza strain have limited boosting ability and limited cross reactivity to other strains. Clin. Microbiol. Infect. 16: 1179-1186. Zahariadis G, Joffe AR, Tablot J, deVilliers A, Campbell P, Pabbaraju K, Wong S, Bastien N, Li Y, Mitchell R, Pang X, Yanow S, Chui L, Predt G, Willans D, Lee B, Preiksaitis J, and Fonsca K. (2010). Identification and epidemiology of severe respiratory disease due to novel swine-origin influenza A (H1N1) virus infection in Alberta. Can J Infect Dis Med Microbiol.. 21(4): e151-e157. Okomo-Adhiambo M, Sleeman K, Ballenger K, Nguyen HT, Mishin VP, Sheu TG, Smagala J, Li Y, Klimov AI and Gubareva LV (2010). Neuraminidase inhibitor susceptibility testing in human influenza viruses: a laboratory surveillance perspective. Viruses. 2: 2269-2289. Douville DN, Lissitsyn Y, Hirschfeld AF, Becker A, Kozyrskyj A, Liem J, Bastien N, Li Y, Victor RE, Sekhon M, Turvey SE, and HayGlass K (2010). TLR4 Asp299Gly and Thr399Ile Polymorphisms: No Impact on Human Immune Responsiveness to LPS or Respiratory Syncytial Virus. PLoS One. Aug 10;5(8). pii; e12087. Kropp RY, Bogaert LE, Barber R, Tremblay FW, Ennis R, Tepper M, Pless R, Bastien N, Li Y, Beaudoin C, Anderson J, Pelletier L, and Rodin R. (2010). Pandemic (H1N1) 2009 outbreak at a Canadian forces cadet camp.Emerg Infect Dis.16(12): 1986-1989. Michaiski CJ, Li Y, and Kang CY. (2010). Induction of cytopathic effects and apoptosis in Spodoptera frugiperda cells by the HIV-1 Env glycoprotein signal peptide. Virus Genes. 41 (3): 341-350. Luo L, Nishi K, MacLeod E, Sabara IM, and Li Y. (2010). Analysis of expression and glycosylation of avian metapneumovirus attachment glycoprotein from recombinant baculovirus. Virus Research.153(2): 244-249. Safronetz D, Rockx B, Feldmann F, Belisle SE, Palermo RE, Brining D, Gardner D, Proll SC, Marzi A, Tsuda Y, Lacasse RA, Kercher L, York A, Korth MJ, Long D, Rosenke R, Shupert WL, Alpuche Aranda C, Mattoon JS, Kobasa D, Kobinger G, Li Y, Taubenberger JK, Richt JA, Parnell M, Ebihara H, Kawaoka Y, Katze MG, and Feldmann H. (2011). Pandemic swine-origin H1N1 influenza A isolates show heterogeneous virulence in macaques. J. Virol. 85(3): 1214-1223. Skowronski DM, Janjua NZ, De Serres G, Hottes TS, Dickinson J, Crowcroft N, Kwindt TL, Tang P, Charest H, Fonseca K, Gubbay J, Bastien N, Li Y, and Petric M. (2011). Effectiveness of AS03-adjuvanted pandemic H1N1 vaccine: estimates from the sentinel system in Canada, fall 2009. BMJ. 342: c7297.