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研究领域

Clinical pharmacokinetics and evaluation of the prophylactic and therapeutic efficacy of antiviral drugs and viral vaccines. Population-based studies of antiviral drug epidemiology and selected bacterial and viral infections

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Aoki FY, Sitar DS. Amantadine kinetics in healthy elderly men: implications for influenza prevention. Clin Pharmacol Ther 1985; 37:137-144. Aoki FY, Tyring S, Diaz-Mitoma F, Gross G, Joseph Gao J, Hamed K. Single-day, patient-initiated famciclovir therapy for recurrent genital herpes: A randomized, double-blind, placebo-controlled trial. Clin Inf Dis 2006; 42:6-13. Bodsworth N, Bloch M, McNulty A, Denham I, Doong N, Trottier S, Adena M, Bonney M-A, Agnew J and the Australo-Canadian FaST (Famciclovir Short-Course Herpes Therapy Study Group (Aoki FY, member). 2-day versus 5-day famciclovir as treatment of recurrences of genital herpes: results of the FaST study. Sexual Health 2008; 5:219-225. Loeb M, Russell ML, Moss L, Fonesca K, Fox J, Earn DJD, Aoki FY, Horsman G, Van Caeseele P, Chokani K, Vooght M, Babiuk L, Webby R, Walter SD. Effect of influenza vaccination of children on infection rates in Hutterite communities. JAMA 2010; 303:943-950. Langley JM, Aoki FY, Ward BJ et al. A nasally administered trivalent inactivated influenza vaccine is well tolerated, stimulates both mucosal and systemic immunity, and potentially protects against influenza illness. Vaccine 2011; DOI:10.1016/j.vaccine.2010.12.100. Lam H, Jeffery J, Sitar D, Aoki FY. Oseltamivir, an influenza neuraminidase inhibitor drug, does not affect the steady-state pharmacokinetic characteristics of cyclosporine, mycophenolate, or tacrolimus in adult renal transplant patients. Ther Drug Monit 2011; 33:699-704. DOI: 10.1097/FTD.0b103e3182399448. Wheeler CM, Castellsagué X, Garland SM, Szarewski A, Paavonen J, Naud P, Salmerón J, Chow S-N, Apter D, Kitchener H, Teixeira JC, Skinner SR, Jaisamrarn U, Limson G, Romanowski B, Aoki FY, Schwarz TF, Poppe WA, Bosch FX, Harper DM, Huh W, Hardt K, Zahaf T, Descamps D, Struyf F, Dubin G, Lehtinen M, for the HPV PATRICIA Study Group. Cross-protective efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: end-of-study (4-year) analysis of the randomised, double-blind PATRICIA trial. Lancet Oncol 2012; 13:100-110. DOI: 10.10106/S1470-20451(11)70287. Aoki, FY, Allen UD, Stiver, HG, Evans GA. The use of antiviral drugs for influenza: Guidance for practitioners 2012/2013. Can J Infect Dis Med Microbiol 2012; 23(4):e79-e92.

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