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An LC/MS/MS method for the simultaneous determination of individual sphingolipid species in B cells. Mi S, Zhao YY, Dielschneider RF, Gibson SB, Curtis JM. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 15;1031:50-60. doi: 10.1016/j.jchromb.2016.07.028. Epub 2016 Jul 16. Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Ma S, Henson ES, Chen Y, Gibson SB. Cell Death Dis. 2016 Jul 21;7:e2307. doi: 10.1038/cddis.2016.208. Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia. Chen Y, Henson ES, Xiao W, Huang D, McMillan-Ward EM, Israels SJ, Gibson SB. Autophagy. 2016 Jun 2;12(6):1029-46. doi: 10.1080/15548627.2016.1164357. Epub 2016 May 11. Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells. Chen Y, Henson ES, Xiao W, Shome E, Azad MB, Burton TR, Queau M, Sathya A, Eisenstat DD, Gibson SB. Cancer Biol Ther. 2016 Jun 2;17(6):604-13. doi: 10.1080/15384047.2015.1095399. Epub 2015 Oct 15. Comparison of outcome of patients with CLL who are referred or nonreferred to a specialized CLL clinic: a Canadian population-based study. Beiggi S, Banerji V, Deneka A, Griffith J, Gibson SB, Johnston JB. Cancer Med. 2016 Jun;5(6):971-9. doi: 10.1002/cam4.559. Epub 2016 Feb 18. Dielschneider, R.F., Eisenstat, H., Mi, S. Curtis, J.M., Xiao, W., Johnston, J.B., and Gibson SB 2015 Lysomostropic Agents Selectively Target Chronic Lymphocytic Leukemia Cells Due to Altered Sphingolipid Metabolism. Leukemia In press Li, H., Wu, X., Hou, S., Noh, E., Makondo, K., Du, Q., Wilkins, JA, Johnston, JB, Gibson SB, Lin, F. and Marshall, AJ 2015 Phosphatidylinositol-3,4-biphosphate and its binding protein lamellipodin regulate chemotaxis of malignant B lymphocytes. Journal of Immunology In press Chen, Y., Henson, E.S., Huang, D. and Gibson SB 2015 Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia. Autophagy In press Chen, Y., Henson, E.S., Xiao, W., Shome, E., Azad, M.B., Burton, T.R., Queau, M., Sathya, A., Eisenstat, D.D., and Gibson SB 2015 Bcl-2 family member Mcl-1 expression is reduced under hypoxia by E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells. Cancer Biology Therapy In press Lafarge ST, Hou S, Pauls SD, Johnston JB, Gibson SB, Marshall AJ. Differential expression and function of CD27 in chronic lymphocytic leukemia cells expressing ZAP-70. Leuk Res. 2015 Jul;39(7):773-8. doi: 10.1016/j.leukres.2015.04.016. Epub 2015 May 2. Ali JL, Lagasse BJ, Minuk AJ, Love AJ, Moraya AI, Lam L, Arthur G, Gibson SB, Morrison LC, Werbowetski-Ogilvie TE, Fu Y, Nachtigal MW.Differential cellular responses induced by dorsomorphin and LDN-193189 in chemotherapy-sensitive and chemotherapy-resistant human epithelial ovarian cancer cells. Int J Cancer. 2015 Mar 1;136(5):E455-69. doi: 10.1002/ijc.29220. Epub 2014 Sep 26. Lafarge ST, Li H, Pauls SD, Hou S, Johnston JB, Gibson SB, Marshall AJ. ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells. Br J Haematol. 2015 Jan;168(1):139-42. doi: 10.1111/bjh.13063. Epub 2014 Aug 4. No abstract available. Shi RY, Zhu SH, Li V, Gibson SB, Xu XS, Kong JM. BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke.CNS Neurosci Ther. 2014 Dec;20(12):1045-55. doi: 10.1111/cns.12325. Epub 2014 Sep 17. Lu P, Kamboj A, Gibson SB, Anderson CM. Poly(ADP-ribose) polymerase-1 causes mitochondrial damage and neuron death mediated by Bnip3.J Neurosci. 2014 Nov 26;34(48):15975-87. doi: 10.1523/JNEUROSCI.2499-14.2014. Dielschneider RF, Xiao W, Yoon JY, Noh E, Banerji V, Li H, Marshall AJ, Johnston JB, Gibson SB. Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling.Cell Death Dis. 2014 Oct 2;5:e1439. doi: 10.1038/cddis.2014.391. Gehrke I, Bouchard ED, Beiggi S, Poeppl AG, Johnston JB, Gibson SB, Banerji V. On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.Clin Cancer Res. 2014 Sep 15;20(18):4861-72. doi: 10.1158/1078-0432.CCR-14-0624. Epub 2014 Aug 29. Schacter JL, Henson ES, Gibson SB.Estrogen regulation of anti-apoptotic bcl-2 family member mcl-1 expression in breast cancer cells.PLoS One. 2014 Jun 27;9(6):e100364. doi: 10.1371/journal.pone.0100364. eCollection 2014. Minuk GY, Lerner B, Gibson SB, Johnston JB, Uhanova J, Andonov A, Wu J. Hepatitis B and hepatitis C viral infections in patients with chronic lymphocytic leukemia. Can J Gastroenterol Hepatol. 2014 Mar;28(3):131-4. Yoon JY, Szwajcer D, Ishdorj G, Benjaminson P, Xiao W, Kumar R, Johnston JB, Gibson SB. Synergistic apoptotic response between valproic acid and fludarabine in chronic lymphocytic leukaemia (CLL) cells involves the lysosomal protease cathepsin B. Blood Cancer J. 2013 Oct 18;3:e153. doi: 10.1038/bcj.2013.50. Yoon JY, Ishdorj G, Graham BA, Johnston JB, Gibson SB. Valproic acid enhances fludarabine-induced apoptosis mediated by ROS and involving decreased AKT and ATM activation in B-cell-lymphoid neoplastic cells. Apoptosis. 2014 Jan;19(1):191-200. doi: 10.1007/s10495-013-0906-7. Lafarge ST, Johnston JB, Gibson SB, Marshall AJ. Adhesion of ZAP-70+ chronic lymphocytic leukemia cells to stromal cells is enhanced by cytokines and blocked by inhibitors of the PI3-kinase pathway.Leuk Res. 2014 Jan;38(1):109-15. doi: 10.1016/j.leukres.2013.08.001. Epub 2013 Aug 9. Beiggi S, Johnston JB, Seftel MD, Pitz MW, Kumar R, Banerji V, J Griffith E, Gibson SB.Increased risk of second malignancies in chronic lymphocytic leukaemia patients as compared with follicular lymphoma patients: a Canadian population-based study. Br J Cancer. 2013 Jul 16. doi: 10.1038/bjc.2013.381. [Epub ahead of print] Gibson SB. Investigating the role of reactive oxygen species in regulating autophagy. Methods Enzymol. 2013;528:217-35. doi: 10.1016/B978-0-12-405881-1.00013-6. Kriangkum J, Motz SN, Debes Marun CS, Lafarge ST, Gibson SB, Venner CP, Johnston JB, Belch AR, Pilarski LM. Frequent occurrence of highly expanded but unrelated B-cell clones in patients with multiple myeloma. PLoS One. 2013 May 28;8(5):e64927. doi: 10.1371/journal.pone.0064927. Print 2013. Burton, T. R., Henson, E.S., Azad, M.B., Brown, M., Eisenstat, D.D. and Gibson, S.B. 2013 BNIP3 acts as transcriptional repressor of Death Receptor 5 (DR5) expression and prevents TRAIL induced cell death in gliomas. Cell Death and Disease 4:e587