个人简介
Dr. Hao Ding received his Bachelor of Medicine from the Shanghai Medical University, China (1987); and his Ph.D. degree on Molecular Biology from the University of Leuven, Belgium (1997). His post-doctoral training (between 1997 and 2004) was done in the labs of Drs. Andras Nagy and Abhijit Guha at the Samuel Lunenfeld Research Institute, Toronto. In 2004, he was awarded a Canada Research Chair and had established his research laboratory at the Department of Biochemistry and Medical Genetics, University of Manitoba and is currently an Associate Professor
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Vannier, J.B., Sandhu, S., Petalcorin, M., Wu, X., Nabi, Z., Ding, H*., Boulton, S.J*. RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science, 2013, 342(6155):239-242 *shared corresponding authorship
Vannier, J.B., Pavicic-Kaltenbrunner, V., Petalcorin, M., Ding, H., Boulton, S.J. RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell, 2012, 149 (4):795-806
Nicklas, S., Otto, A., Wu, X., Miller, P., Stelzer, S., Wen, Y., Kung, S., Wrogemann, K., Patel, K., Ding, H*., Schwamborn, J.C*. TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. Plos One, 2012, 7(1):e30445 *shared corresponding authorship
Wu, X., Sandhu, S., Nabi, Z., Ding, H. Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis. Transgenic Res., 2012, 5:1109-1115
Sandhu, S., Wu, X., Nabi, Z., Rastegar, M., Kung, S., Mai, S., Ding, H. Loss of HLTF promotes intestinal carcinogenesis. Mol Cancer, 2012, 11:18