Arthur, Gilbert - University of Manitoba - Department of Biochemistry and Medical Genetics

个人简介

Dr. Gilbert Arthur received his B.Sc. degree from the University of Ghana in Accra, Ghana, and his Ph.D. degree from the University of Leeds in England. He moved to Winnipeg to do his post-doctoral training with Dr. P. C. Choy at the University of Manitoba in the area of phospholipid metabolism in the heart with special emphasis on plasmalogens. Dr. Arthur is currently a Professor in the Department of Biochemistry and Medical Genetics at the University of Manitoba

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Samadder P, Xu Y, Schweizer F, Arthur G. Cytotoxic properties of D-gluco-, D-galacto- and D-manno-configured 2-amino-2-deoxy-glycerolipids against epithelial cancer cell lines and BT-474 breast cancer stem cells. Eur J Med Chem. 2014 May 6;78:225-35. PMID:24681987 Samadder P, Bittman R, Byun HS, Arthur G. A glycosylated antitumor ether lipid kills cells via paraptosis-like cell death. Biochem Cell Biol. 2009 Apr;87(2):401-14. PMID:19370058 Lin W, Arthur G. Phospholipids are synthesized in the G2/M phase of the cell cycle. Int J Biochem Cell Biol. 2007;39(3):597-605. PMID:17113814 Zhou X, Lu X, Richard C, Xiong W, Litchfield DW, Bittman R, Arthur G. 1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells. J Clin Invest. 1996 Aug 15;98(4):937-44. PMID:8770865 Erukulla RK, Zhou X, Samadder P, Arthur G, Bittman R. Synthesis and evaluation of the antiproliferative effects of 1-O-hexadecyl-2-O-methyl-3-O-(2'-acetamido-2'-deoxy-beta-D- glucopyranosyl)-sn-glycerol and 1-O-hexadecyl-2-O-methyl-3-0- (2'-amino-2'-deoxy-beta-D-glucopyranosyl)-sn-glycerol on epithelial cancer cell growth. J Med Chem. 1996 Mar 29;39(7):1545-8. PMID:8691486