Lalji, Fawziah - University of British Columbia - Faculty of Pharmaceutical Sciences

个人简介

Dr. Fawziah Lalji (Marra) obtained her bachelor of science in pharmacy and doctor of pharmacy at UBC. She subsequently completed a two-year fellowship in infectious diseases pharmacotherapy at the Vancouver General Hospital. She is a professor in the Faculty of Pharmaceutical Sciences at UBC and has practiced infectious diseases pharmacotherapy within both the acute care (hospital) sector and public health (at the BC Centre for Disease Control). Dr. Lalji's work at the BC Centre for Disease Control allowed her to focus on applied research around population and public health of communicable diseases. Thus, much of Dr. Lalji's work focuses on health outcomes associated with immunizations and treatment of tuberculosis, and it directly translated to changes in policy within British Columbia. Dr. Lalji's uses British Columbia's administrative databases for pharmacoepidemiological evaluation as well as health economic modelling, particularly for vaccine-preventable diseases. She has published over 200 peer-reviewed papers, book chapters and research abstracts in prestigious medical journals, and has been a recipient of many research awards.

研究领域

Applied research around population and public health of communicable diseases has been the focus of Dr. Lalji's research for most of her career. Together with her colleagues at the BC Centre for Disease Control, she has published numerous studies that evaluate the effectiveness and cost-effectiveness of new therapies in individuals with tuberculosis and immunization. She is well-versed in the use of large administrative databases to conduct pharmacoepidemiological evaluations, such as the studies on the use of antivirals in preventing hospitalizations during the H1N1 pandemic, the delay in diagnosis of TB, use of antibiotics and development of asthma, use of various antibiotics for urinary tract infections, skin and soft tissue infections and upper respiratory tract infections. Some of the pharmacoepidemiological data obtained from the administrative databases (such as incidence of disease, health outcomes, resource utilization, length of stay, and cost to the health care system) is paired with quality of life data to build economic models that use real data to implement new policies around communicable disease control. Evidence of such models include publications on the cost-effectiveness of switching to a new but more costly diagnostic test, Quantiferon Gold, cost-effectiveness of latent tuberculosis infection (LTBI) treatment for contacts, and cost-effectiveness of various immunizations. Current research projects include building a cost-effectiveness model for foreign born patients who have been exposed to LTBI, epidemiology of herpes zoster infections in BC, risk of zoster following immunosuppressive conditions and/or medications, epidemiology of community-acquired Clostridium difficile infections, meta-analysis on antibiotics used for C. difficile treatment, and adverse event reporting of influenza immunizations by pharmacists.

近期论文

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A Systematic Review on TST and IGRA Tests Used for Diagnosis of LTBI in Immigrants, Campbell, Jonathon R., Krot Jane, Elwood Kevin, Cook Victoria, and Marra Fawziah , Molecular Diagnosis & Therapy, Jan-02-2015, Volume 19, Issue 1, p.9 - 24, (2015) Effectiveness of neuraminidase inhibitors in preventing hospitalization during the H1N1 influenza pandemic in British Columbia, Canada, Marra, F., Chong M., Henry B., Patrick D. M., and Kendall P. , Journal of Antimicrobial Chemotherapy, Jan-05-2014, Volume 69, Issue 5, p.1397 - 1406, (2014) Screening immigrants for latent tuberculosis: Do we have the resources?, Campbell, J., Marra F., Cook V., and Johnston J. , Canadian Medical Association Journal, Apr-03-2014, Volume 186, Issue 4, p.246 - 247, (2014) Immunogenicity of 2 Doses of HPV Vaccine in Younger Adolescents vs 3 Doses in Young Women, Dobson, Simon R. M., McNeil Shelly, Dionne Marc, Dawar Meena, Ogilvie Gina, Krajden Mel, Sauvageau Chantal, Scheifele David W., Kollmann Tobias R., Halperin Scott A., et al. , JAMA, Jan-05-2013, Volume 309, Issue 17, p.1793, (2013) Population-Based Study of the Increased Incidence of Skin and Soft Tissue Infections and Associated Antimicrobial Use, Marra, F., Patrick D. M., Chong M., McKay R., Hoang L., and Bowie W. R. , Antimicrobial Agents and Chemotherapy, Jan-12-2012, Volume 56, Issue 12, p.6243 - 6249, (2012)