个人简介

Postdoctoral Fellow, Biology, Princeton University, 2013 Ph.D., Chemistry, New York University, 2009 B.S., Chemistry, Lanzhou University, 2001

研究领域

Biochemistry/Polymer/Materials

Programming synthetic biomolecules to fabricate novel nanostructures / devices that work for sensors, drug delivery systems, and biophysical studies of protein-protein and other macromolecular interactions at the single molecule level. Molecular engineering at the genome level to transform live eukaryotic cells to study in vivo functional biomaterials self-assembly for the potential to edit cell metabolism, RNA-mediated therapeutics, and creation of novel proteins. Non-coding RNA (both long and short) mediated epigenetic inheritance in the ciliate Oxytricha Trifallax.

近期论文

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Fang, Wang, Bracht, Nowacki, and Landweber, Piwi-interacting RNAs protect DNA against loss during Oxytricha genome rearrangement, Cell, 151, 1243-1255 (2012). Wang, Zhang, Mao, and Seeman, Double-stranded DNA homology produces a physical signature, PNAS, 107, 12547-12552 (2010). Wang, Lin, Rinker, Liu, Seeman, and Yan, In vivo cloning of artificial DNA nanostructures, PNAS, 105, 17626-17632 (2008). Liu, Wang, Wang, Sha, and Seeman, PX DNA triangle oligomerized using a novel three-domain motif, Nano Letters, 8, 317-322 (2008). Lin, Wang, Liu, Seeman, and Yan, Rolling circle enzymatic replication of a complex multi-crossover DNA nanostructure, JACS, 129,14475-14481 (2007). Wang, and Seeman, Assembly and characterization of 8-Arm and 12-Arm DNA branched junctions, JACS, 129, 8169-8176 (2007).