Morck, Douglas Walter - University of Calgary - Department of Biological Sciences

个人简介

PhD - Pathogenesis of Bovine Pasteurellosis University of Calgary, 1991 DVM University of Saskatchewan, 1987 BSc - Cellular, Microbial and Microbiology University of Calgary, 1983

研究领域

Antibiotic Resistance Pathogenic mechanisms in infectious disease Treatment of infectious disease Biofilms and medical device-related infection

近期论文

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Duquette SC, Fischer CD, William AC, Sajedy S, Feener TD, Bhargava A, Reti KL, Muench GP, Morck DW, Allison J, Lucas MJ, Buret AG. Immunomodulation by antibiotics: tulathromycin promotes porcine neutrophil apoptosis, enhances efferocytosis and inhibits pro-inflammatory leukotriene B4 production in Actinobacillus pleuropneumoniae- and zymosan-challenged piglets. (Submitted 2014 Amer J Vet Res) Duquette SC, Fischer CD, Feener TD, Muench GP, Morck DW, Barreda DR, Nickerson JG, Buret AG. Anti-inflammatory effects of retinoids and carotenoid derivatives on caspase-3-dependent apoptosis and efferocytosis of bovine neutrophils. Amer J Vet Res 2014; 75(12):1064-75 Fischer CD, Duquette SC, Renaux BS, Feener TD, Morck DW, Hollenberg MD, Lucas MJ, Buret AG. Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production. Antimicrob Agents Chemother 2014;58(8):4298-4307 Fischer CD, Beatty JK, Duquette SC, Morck DW, Lucas MJ, Buret AG. Direct and indirect anti-inflammatory effects of tulathromycin in bovine macrophages: inhibition of CXCL-8 secretion, induction of apoptosis, and promotion of efferocytosis. Antimicrob Agents Chemother 2103;57(3):1385-1393 Holland S, Morck D, Schultz C. Treatment of corneal defects with delayed re-epithelialization with a medical device/drug delivery system for epidermal growth factor. Clin Experiment Ophthalmol 2012;40(7):662-668 D’Amours GH, Ward TI, Mulvey MR, Read RR, Morck DW. Genetic diversity of tetracycline resistant genes in Histophilus somni. Vet Microbiol 2011;150(3-4):362-372 Schultz C, Breaux J, Schentag J, Morck DW. Drug delivery to the posterior segment of the eye through hydrogel contact lenses. Clin Exp Optom 2011;94(2):212-218 Fischer CD, Beatty JK, Zvaigne C, Morck DW, Lucas MJ, Buret AG. Anti-inflammatory benefits of antibiotic-induced neutrophil apoptosis: tulathromycin induces caspase-3-dependent neutrophil programmed cell death and inhibits NF-kappaB signaling and CXCL-8 transcription. Antimicrob Agents Chemother 2011;55(1):338-348 Mataseje LF, Baudry PJ, Zhanel GG, Morck DW, Read RR, Louie M, Mulvey M. Comparison of CMY-2 plasmids isolated from human, animal and environmental Escherichia coli and Salmonella spp from Canada. Diag Microbiol Infect Dis. 2010;67(4):387-391 Chan E, Goldstein D, Ceri H, Costerton JW, Morck DW, Schultz C. Biofilm development on a post subsequent to leakage of the core buildup: a case report. General Dentistry. 2010 (July/August) e184-e186 Boothe J, Nykiforuk C, Shen Y, Zaplachinski S, Szarka S, Kuhlman P, Murray E, Morck DW, Moloney MM. Seed-based expression systems for plant molecular farming. Plant Biotechnology Journal. 2010;8:588-606 Schultz CI, Morck DW. Contact lenses as a drug delivery device for epidermal growth factor in the treatment of ocular wounds. Clin Exp Optom. 2010:93(2):61-65 Sweeney M, Watts J, Portis E, Lucas M, Nutsch R, Meeuwse D, Bade D, Oliver V, Morck DW, Shinabarger D, Poppe S, Peterson M, Sweeney D, Knechtel M, Zurenko G. Identification ofPorphyromonas levii isolated from clinical cases of bovine interdigital necrobacillosis by 16S rRNA sequencing. Veterinary Therapeutics. 2010;10(4):E1-E10 Mulvey MR, Susky E, McCracken M, Morck DW, Read RR. Similar cefoxitin resistance plasmids circulating in Escherichia coli from human and animal sources in Canada. Vet Microbiol 2009 Mar 2;134(3-4):279-87 Hecker K, Donnon T, Fuentealba C, Hall D, Illanes O, Morck DW, Muelling C. Assessment of applicants to the veterinary curriculum using a multiple mini-interview. J Vet Educ 2009;36(2):166-172. Alexander TW, Yanke LJ, Topp E, Olson ME, Morck DW, Read RR, McAllister TA. Effect of subtherapeutic administration of antibiotics on the prevalence of antibiotic-resistant Escherichia coli in feedlot cattle.Appl Environ Microbiol. 2008; 74(14):4405-16 Hoar BM, Whiteside DP, Ward L, Inglis GD, Morck DW. Evaluation of the normal enteric microflora of captive whooping cranes (Grus Americana) and sandhill cranes (Grus canadensis). Zoo Biology 2007;26:141-153 Mills SW, Montgomery SH, Morck DW. Short chain fatty acids and extracellular pH modulate bovine neutrophil function in vitro. Am J Vet Res 2006;67:1901-1907 Inglis GD, Morck DW, McAllister TA, Entz T, Olson ME, Yanke LJ, Read RR. Temporal prevalence of antimicrobial resistance in Campylobacter spp. From beef cattle in Alberta feedlots. Appl Environ Microbiol 2006;72:4088-4095