Zhang, Donghui - Louisiana State University

个人简介

Bachelor's Degree(s): Peking University, 1998 PhD: Dartmouth College, 2003 PostDoc: University of Minnesota, 2003-2005

研究领域

Our group is interested in the development of new controlled polymerization methods that enable the synthesis of functional polymers with novel architectures and conformations, and the fundamental structure-property studies of these polymers. Insight obtained from the studies will provide feedback on the design of the polymer structure and ultimately facilitates their transition to practical applications. The multidisciplinary nature of the program entails various modern synthetic techniques and physical characterization methods, and requires an understanding of materials science and engineering. Current projects include (1) development of catalytic reactions towards peptidomimetic polymers (e.g., polypeptoids and polypeptides); (2) synthesis and characterization of functional polypeptoids and polypeptides; (3) solution properties of peptidomimetic polymers; (4) design and synthesis of water soluble peptidomimetic polymers for biotechnological applications.

近期论文

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Cao, J.; Hu, P.; Lu, L.; Chan, B. A.; Luo, B.-H.; Zhang, D.* Non-Ionic Water-Soluble “Clickable” α-Helical Polypeptides: Synthesis, Characterization and Side Chain Modification. Polym. Chem.2015, DOI: 10.1039/C4PY01560F Reyes, F. T.; Guo, L.; Hedgepeth, J. W.; Zhang, D.; Kelland, M. A.* The First Investigation of Kinetic Hydrate Inhibitor Performance of Poly(N-alkyl glycine)s. Energy & Fuels, 2014, 28, 6889-6896 Tang, H.*;Ling, Y.; Deng, Y.; Zhang, D.* Synthesis and Solid-State Self-Assembly of Poly(ethylene glycol)-b-poly(g-benzyl-L-glutamate)s and Single-Walled Carbon Nanotubes. J. Polym. Sci. A Polym. Chem.2014, 52,1905-1915 Lahasky, S. H.; Lu, L.; Huberty, W. A.; Cao, J.; Guo, L.; Garno, J. C.; Zhang, D.* Synthesis and Characterization of Thermo-responsive Polypeptoid Bottlebrushes. Polym. Chem. 2014, 5,1418-1429 Lee, C.-U.; Li, A.; Ghale, K.; Zhang, D.* “Crystallization and Melting Behaviors of Cyclic and Linear Polypeptoids with Alkyl Side Chains.” Macromolecules 2013, 46, 8213-8223 Tang, H.*; Zhang, D.* “Solid State Self-Assembly of Single-Walled Carbon Nanotubes and Poly(γ-benzyl-L-glutamate)s with Different Conformations.” J. Polym. Sci. A. Polym. Chem. 2013, 51, 4489-4497 Lee, C. -H.; Lu, L.; Chen, J.; Garno, J. C.; Zhang, D.* "Crystallization-Driven Thermo-Reversible Gelation of Coil-Crystalline Cyclic and Linear Diblock Copolypeptoids.” ACS Macro Lett. 2013, 2, 436-440 Zhang, D.;* Lahasky, S. H.; Guo, L.; Lee, C.-U.; Lavan, M. “Polypeptoid Materials: Current Status and Future Perspectives.” Macromolecules 2012, 45, 5833-5841 Guo, L.; Lahasky, S. H.; Ghale, K.; Zhang, D.* “N-Heterocyclic Carbene-Mediated Zwitterionic Polymerization of N-substituted N-carboxyanhydrides towards Poly(α-peptoid)s: Kinetic, Mechanism and Architectural Control.” J. Am. Chem. Soc. 2012, 134, 9163-9171 Lahasky, S. H.; Hu, X.; Zhang, D.* “Thermoresponsive Poly(α-peptoid)s: Tuning the Cloud Point Temperatures by Composition and Architecture.” ACS Macro Lett. 2012, 1, 580-584 Lee, C.-U.; Smart, T. P.; Guo, L.; Epps, T. H., III; Zhang, D.* “Synthesis and Characterization of Amphiphilic Cyclic Diblock Copolypeptoids from N-Heterocyclic Carbene-Mediated Zwitterionic Polymerization of N-Substituted N-Carboxyanhyrdride.” Macromolecules 2011, 44, 9574-9585 Lahasky, S. H.; Serem, W. K.; Guo, L.; Garno, J. C. Zhang, D.* “Synthesis and Characterization of Cyclic Brush-Like Polymers by N-Heterocyclic Carbene-Mediated Zwitterionic Polymerization of N-Propargyl N-Carboxyanhyrdride and the Grafting-to Approach.” Macromolecules 2011, 44, 9063-9074 Li, X.; Guo, L.; Casiano-Maldonado, M; Zhang, D.; Westdemiotis, C.* “Top-Down Multi-Dimensional Mass Spectrometry Methods for Synthetic Polymer Analysis.” Macromolecules 2011, 44, 4555-4564 Tang, H.; Lee, C. -U.; Zhang, D.* “Thermoreversible Gelation of Helical Polypeptide/Single-Walled Carbon Nanotubes and their Solid-State Structures.” J. Polym. Sci. A. Polym. Chem. 2011, 49, 3228-3238 Tang, H.; Li, Y.; Lahasky, S. H.; Sheiko, S. S.; Zhang, D.* “Core-Shell Molecular Bottlebrushes with Helical Polypeptide Backbone: Synthesis, Characterization and Solution Conformations.” Macromolecules 2011, 44, 1491-1499 Tang, H.; Zhang, D.* “Multi-Functionalization of Helical Block Copoly(α-peptide)s with Orthogonal Chemistry.” Polym. Chem. 2011, 2, 1542-1551 Guo, L. Zhang, D.* “Synthesis and Characterization of Helix-Coil Block Copoly(α-peptoid)s.” ACS Symposium Series on Non-conventional Functional Block Copolymers. 2011, Ch.6, 71-79 Guo, L.; Li, J.; Brown, Z.; Ghale, K.; Zhang, D.* “Synthesis and Characterization of Cyclic and Linear Helical Poly(α-peptoid)s by N-Heterocyclic Carbene-Mediated Ring-Opening Polymerization of N-Substituted N-Carboxylanhydrides.” Biopolym.: Peptide Science 2011, 96, 596-603 Tang, H.; Zhang, D.* “General Route towards Side-Chain-Functionalized alpha-Helical Polypeptides.” Biomacromolecules 2010, 11, 1585-1592 Tang, H.; Zhang, D.* “Poly(gamma-benzyl-L-glutamate)-Functionalized Single-Walled Carbon Nanotubes. Synthesis, Characterization and Materials Properties.” J. Polym. Sci. A Polym. Chem. 2010, 48, 2340-2350 Guo, L.; Zhang, D.* “Cyclic Poly(alpha-peptoid)s and Their Block Copolymers from N-Heterocyclic Carbene- Mediated Ring-Opening Polymerization of N-Substituted N-Carboxylanhydrides.” J. Am. Chem. Soc. 2009, 131, 18072-18074