Chen, Peng - Nanyang Technological University - School of Chemical and Biomedical Engineering

研究领域

1. Developing novel biosensors based on nanostructured materials Nanostructured materials such as nanoparticles, nanopores, carbon nanotubes, and nanowires are bringing unprecedented opportunities to biology. Their nanoscale dimensions allow them to interact intimately with and spy on the nanoscopic world of biomolecules and molecular machineries. We develop nanoelectronic biosensors based on graphene, carbon nanotubes and silicon nanowires which can detect biomolecules with exquiste sensitivity, and can interface with living cells for the detection of cellular activities, such as, biomolecular release and ion channel activities. 2. Studies on exocytosis (or regulated cell secretion) and adipobiology We study the mechanisms of exocytosis, the fundamental process underlying hormone secretion from endocrine cells and neurotransmitter secretion from neurons, using integative methods including bio-imaging (confocal microscopy, total internal reflection fluorescence microscopy, Ca imaging), electrochemistry (micro-carbon-fiber amperometry), and biophysics (patch-clamp), and nanotechnologies (“Micro and Nanotechnologies for Study of Cell Secretion”, Analytical Chemistry, 83(12):4393-4406, 2011). More recently, we focus on investigating the regulated secretion of adipokines from adiocytes, and their involvements in metabolism and metabolic diseases (e.g., obesity and diabetes). 3. Applying nanomaterilas for energy storage and conversion We synthesize and functionalize nanomaterials (e.g., graphene, carbon nanotubes) and use them for energy applications, such as, supercapacitor, biofuel cells, and fuel cells.

近期论文

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Xu R, Jiang T, Fu Z, Cheng N, Zhang X, Zhu K, Xue H, Wang W, Tian J, and Chen P*, “Ion-exchange controlled surface engineering of cobalt phosphide nanowires for enhanced hydrogen evolution” Nano Energy, (accepted), 2020 Liang C, Zhang X, Yang M, Wang W, Chen P*, and Dong X, “Remodeling Tumor Microenvironment by Multifunctional Nanoassemblies for Enhanced Photodynamic Cancer Therapy”, ACS Materials Letters, (accepted), 2020 Than A, Duong PK, Zan P, Liu J, Leow MKS, Chen P*, “Lancing drug-reservoirs into subcutaneous fat to combat obesity and associated metabolic diseases”, Small, 16(31):2002872, 2020 Than A, Zang P, Chen P*, “Transdermal Theranostics”, View, 1:e21, 2020 Yan Y, Zeng Z, Huang M, Chen P*, “Van der waals heterojunctions for catalysis”, Materials Today Advances, 6:100059, 2020 Yan Y, Zhai D, Liu Y, Gong J, Chen J, Zan P, Zeng Z, Li S, Huang W, and Chen P*, "Van der Waals Heterojunction between Bottom-Up Grown Doped Graphene Quantum Dot and Graphene for Photoelectrochemical Water Splitting", ACS Nano, 14:1185-1195, 2020 Liu G, Zhu J, Guo H, Sun A, Chen P*, Xi L, Huang W, Song X, and Dong X, “Mo2C-Derived Polyoxometalate for NIR-II Photoacoustic Imaging-Guided Chemodynamic/Photothermal Synergistic Therapy”, Angewandte Chemie International Edition, 58:18641-18646, 2019 Zeng Z, Gu G, Yang H, Yan Y, Chen J, Yu Z, Gao J, Gan LY, Liu B, Chen P*, “Bifunctional N-CoSe2/3D-MXene as Highly Efficient and Durable Cathode for Rechargeable Zn-Air Battery”, ACS Materials Letter, 1:432-439, 2019 Chen D, Tang Y, Zhu J, Zhang J, Song X, Wang W, Shao J, Huang W, Chen P*, and Dong X, “Photothermal-pH-hypoxia responsive multifunctional nanoplatform for cancer photo-chemo therapy with negligible skin phototoxicity”, Biomaterials, 221:119422, 2019 Zan P, Than A, Duong PK, Song J, Xu C, and Chen P*, “Antimicrobial Microneedle Patch for Treating Deep Cutaneous Fungal Infection”, Advanced Therapeutics, 1900064, 2019 Yan Y, Gong J, Chen J, Zeng Z, Huang W, Pu K, Liu J, and Chen P*, “Recent Advances on Graphene Quantum Dots: From Chemistry and Physics to Applications”, Advanced Materials, 31:1808283, 2019 Xi F, Zhao J, Shen C, He J, Chen J, Yan Y, Li K, Liu J, and Chen P*, “Amphiphilic Graphene Quantum Dots as a New Class of Surfactants”, Carbon, 153:127-135, 2019 Ge G, Yuan W, Lu Y, Zhang Y, Wang W, Chen P, Huang W, Si W, and Dong X, “Highly Stretchable and Self-healing Flexible Sensor Based on Malleable and Anti-Freezing Binary-Networked Hydrogel”, J. of Mat. Chem. A, 7:56949-5856, 2019 Lu L, Zhou L, Chen J, Yan F, Liu J, Dong X, Xi F, and Chen P*, “Nanochannel-Confined Graphene Quantum Dots for Ultrasensitive Electrochemical Analysis of Complex Samples”, ACS Nano, 12:12673-12681, 2018 Zeng Z, Yan Y, Chen J, Zan P, Tian Q, and Chen P*, “Boosting the Photocatalytic Ability of Cu2O Nanowires for CO2 Conversion by MXene Quantum Dots”, Adv. Func. Mat., 29:1806500, 2019 Than A, Liu C, Chang H, Duong PK, Cheung CMG, Xu C, Wang X, and Chen P*, “Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery”, Nature Communications, 9:4433, 2018 Yan Y, Chen J, Li N, Tian J, Li K, Jiang J, Liu J, Tian Q, and Chen P*, “Systematic Bandgap Engineering of Graphene Quantum Dots and Applications for Photocatalytic Water Splitting and CO2 Reduction”, ACS Nano, 12:3523-3532, 2018 Tian J, Chen J, Tian Q, Liu J, and Chen P*, “Graphene quantum dot engineered nickel-cobalt phosphide as highly efficient bifunctional catalyst for overall water splitting”, Nano Energy, 48:284-291, 2018 Zhu H, Li J, Qi X, Chen P*, Pu K, “Oxygenic Hybrid Semiconducting Nanoparticles for Enhanced Photodynamic Therapy”, Nano Letters, 18: 586–594, 2018 Xu W, Lee TK, Moon BS, Song HW, Chen X, Chen B, Kim YJ, Kwak SK, Chen P*, Kim DH, “Broadband Plasmonic Antenna Enhanced Upconversion and Its Application in Flexible Fingerprint Identification”, Advanced Optical Materials, 6:1701119, 2018