Pittman, Quentin - University of Alberta - Department of Pharmacology

个人简介

Bachelor of Arts and Science - Major in Biology, University of Lethbridge, Lethbridge, 1972 PhD - Medical Physiology, University of Calgary, 1976

研究领域

Research activities focus on central autonomic control of fever, antipyresis and blood pressure and on the synaptic pharmacology of important endocrine and autonomic nuclei such as the supraoptic nucleus of the hypothalamus and the dorsal vagal complex. In addition, we study plasticity of neuronal function during pregnancy and lactation, and study the influence of neonatal immune challenges on adult autonomic function. We are interested in a number of transmitters including: cannabinoids, neuropeptides and amino acids.

近期论文

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D'Mello C, Riazi K, Le T, Stevens KM, Wang A, McKay DM, Pittman QJ, Swain MG. (2013) P-selectin-mediated monocyte-cerebral endothelium adhesive interactions link peripheral organ inflammation to sickness behaviors. J Neurosci. 33(37):14878-88. PMID: 24027287 Moriyama C, Galic MA, Mychasiuk R, Pittman QJ, Perrot TS, Currie RW, Esser MJ. (2013) Prenatal transport stress, postnatal maternal behavior, and offspring sex differentially affect seizure susceptibility in young rats. Epilepsy Behav. 29(1):19-27. PMID: 23920381 Acharjee S, Nayani N, Tsutsui M, Hill MN, Ousman SS, Pittman QJ. (2013) Altered cognitive-emotional behavior in early experimental autoimmune encephalitis--cytokine and hormonal correlates. Brain Behav Immun. 33:164-72. PMID: 23886782 Duncan M, Galic MA, Wang A, Chambers AP, McCafferty DM, McKay DM, Sharkey KA, Pittman QJ. (2013) Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation. Am J Physiol Regul Integr Comp Physiol. 305(3):R224-31. PMID: 23739343 Scullion K, Boychuk JA, Yamakawa GR, Rodych JT, Nakanishi ST, Seto A, Smith VM, McCarthy RW, Whelan PJ, Antle MC, Pittman QJ, Teskey GC. (2013) Serotonin 1A receptors alter expression of movement representations. J Neurosci. 33(11):4988-99. PMID: 23486969 Reid AY, Riazi K, Campbell Teskey G, Pittman QJ. (2013) Increased excitability and molecular changes in adult rats after a febrile seizure. Epilepsia. 54(4):e45-8. PMID: 23293960 Hu H, Ho W, Mackie K, Pittman QJ, Sharkey KA. (2012) Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation. Neuroscience. 227:211-22. PMID: 23041513 Henderson AK, Pittman QJ, Teskey GC. (2012) High frequency stimulation alters motor maps, impairs skilled reaching performance and is accompanied by an upregulation of specific GABA, glutamate and NMDA receptor subunits. Neuroscience. 215:98-113. PMID: 22546338 Rana SA, Aavani T, Pittman QJ. (2012) Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life. Horm Behav. 62(3):228-36. PMID: 22516179 Hons IM, Storr MA, Mackie K, Lutz B, Pittman QJ, Mawe GM, Sharkey KA. (2012) Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterol Motil. 24(3):e113-24. PMID: 22235973 Galic MA, Riazi K, Pittman QJ. (2012) Cytokines and brain excitability. Front Neuroendocrinol. 33(1):116-25. PMID: 22214786 Pittman QJ. (2012) A neuro-endocrine-immune symphony. J Neuroendocrinol. 23(12):1296-7. PMID: 22092721 Reid AY, Pittman QJ, Teskey GC. (2012) A prolonged experimental febrile seizure results in motor map reorganization in adulthood. Neurobiol Dis. 45(2):692-700. PMID: 22044736 Tobin V, Schwab Y, Lelos N, Onaka T, Pittman QJ, Ludwig M. (2012) Expression of exocytosis proteins in rat supraoptic nucleus neurones. J Neuroendocrinol. 24(4):629-41. PMID: 21988098 Vezzani A, Aronica E, Mazarati A, Pittman QJ. (2013) Epilepsy and brain inflammation. Exp Neurol. 244:11-21. PMID: 21985866