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Novel High-throughput Approach for Purification of Infectious Virions. James KT, Cooney B, Agopsowicz K, Trevors MA, Mohamed A, Stoltz D, Hitt M, Shmulevitz M. Sci Rep. 2016 Nov 9;6:36826. doi: 10.1038/srep36826. PMID: 27827454 Free PMC Article Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus Variants. Mohamed A, Johnston RN, Shmulevitz M. Viruses. 2015 Dec 1;7(12):6251-78. doi: 10.3390/v7122936. Review. PMID: 26633466 Free PMC Article Nogo to IFN by Ras. Shmulevitz M, Mohamed A. Cell Cycle. 2015 Aug 3;14(15):2392-3. doi: 10.1080/15384101.2015.1063310. No abstract available. PMID: 26103007 Free PMC Article Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release. Garant KA, Shmulevitz M, Pan L, Daigle RM, Ahn DG, Gujar SA, Lee PW. Oncogene. 2016 Feb 11;35(6):771-82. doi: 10.1038/onc.2015.136. Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma. Cooper T, Biron VL, Fast D, Tam R, Carey T, Shmulevitz M, Seikaly H. J Otolaryngol Head Neck Surg. 2015 Feb 24;44:8. doi: 10.1186/s40463-015-0062-x. PMID: 25890191 Free PMC Article Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells. Mohamed A, Teicher C, Haefliger S, Shmulevitz M. J Virol. 2015 Apr;89(8):4319-34. doi: 10.1128/JVI.03651-14. PMID: 25653434 Free PMC Article Activation of p53 by chemotherapeutic agents enhances reovirus oncolysis. Pan D, Marcato P, Ahn DG, Gujar S, Pan LZ, Shmulevitz M, Lee PW. PLoS One. 2013;8(1):e54006. doi: 10.1371/journal.pone.0054006. PMID: 23342061 Free PMC Article Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation. Gujar S, Dielschneider R, Clements D, Helson E, Shmulevitz M, Marcato P, Pan D, Pan LZ, Ahn DG, Alawadhi A, Lee PW. Mol Ther. 2013 Feb;21(2):338-47. doi: 10.1038/mt.2012.228. PMID: 23299799 Free PMC Article Reovirus variants with mutations in genome segments S1 and L2 exhibit enhanced virion infectivity and superior oncolysis. Shmulevitz M, Gujar SA, Ahn DG, Mohamed A, Lee PW. J Virol. 2012 Jul;86(13):7403-13. doi: 10.1128/JVI.00304-12. PMID: 22532697 Free PMC Article Exploring host factors that impact reovirus replication, dissemination, and reovirus-induced cell death in cancer versus normal cells in culture. Shmulevitz M, Lee PW. Methods Mol Biol. 2012;797:163-76. doi: 10.1007/978-1-61779-340-0_12. PMID: 21948476 Stabilisation of p53 enhances reovirus-induced apoptosis and virus spread through p53-dependent NF-κB activation. Pan D, Pan LZ, Hill R, Marcato P, Shmulevitz M, Vassilev LT, Lee PW. Br J Cancer. 2011 Sep 27;105(7):1012-22. doi: 10.1038/bjc.2011.325. PMID: 21863032 Free PMC Article Oncogenic Ras promotes reovirus spread by suppressing IFN-beta production through negative regulation of RIG-I signaling. Shmulevitz M, Pan LZ, Garant K, Pan D, Lee PW. Cancer Res. 2010 Jun 15;70(12):4912-21. doi: 10.1158/0008-5472.CAN-09-4676. Erratum in: Cancer Res.2010 Aug 1;70(15):6397. PMID: 20501842 Free Article Activated Ras signaling significantly enhances reovirus replication and spread. Shmulevitz M, Marcato P, Lee PW. Cancer Gene Ther. 2010 Jan;17(1):69-70. doi: 10.1038/cgt.2009.46. No abstract available. PMID: 19590528 Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism. Burke SM, Issekutz TB, Mohan K, Lee PW, Shmulevitz M, Marshall JS. Blood. 2008 Jun 15;111(12):5467-76. doi: 10.1182/blood-2007-10-118547. PMID: 18424663 Free Article Leaky scanning and scanning-independent ribosome migration on the tricistronic S1 mRNA of avian reovirus. Racine T, Barry C, Roy K, Dawe SJ, Shmulevitz M, Duncan R. J Biol Chem. 2007 Aug 31;282(35):25613-22. PMID: 17604272 Free Article Ras transformation mediates reovirus oncolysis by enhancing virus uncoating, particle infectivity, and apoptosis-dependent release. Marcato P, Shmulevitz M, Pan D, Stoltz D, Lee PW. Mol Ther. 2007 Aug;15(8):1522-30. PMID: 17457318 Free Article Unshackling the links between reovirus oncolysis, Ras signaling, translational control and cancer. Shmulevitz M, Marcato P, Lee PW. Oncogene. 2005 Nov 21;24(52):7720-8. Review. PMID: 16299532 Membrane metabolism mediated by Sec14 family members influences Arf GTPase activating protein activity for transport from the trans-Golgi. Wong TA, Fairn GD, Poon PP, Shmulevitz M, McMaster CR, Singer RA, Johnston GC. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12777-82. PMID: 16126894 Free PMC Article A newly identified interaction between IVa2 and pVIII proteins during porcine adenovirus type 3 infection. Singh M, Shmulevitz M, Tikoo SK. Virology. 2005 May 25;336(1):60-9. PMID: 15866071 Free Article Connecting reovirus oncolysis and Ras signaling. Marcato P, Shmulevitz M, Lee PW. Cell Cycle. 2005 Apr;4(4):556-9. Review. PMID: 15753655