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Daude, N., Wohlgemuth, S., Pitstick, R., Gapeshina, H., Carlson, G. A. , and Westaway, D. “Knockout of the PrP- like Sprn gene does not produce embryonic lethality in combination with PrPC-deficiency” Proceedings of the National Academy of Sciences USA, 2012 109:1035- 1040. Mays CE, Kim C, Haldiman T, van der Merwe J, Lau A, Yang J, Grams J, Di Bari MA, Nonno R, Telling GC, Kong Q, Langeveld J, McKenzie D, Westaway D, Safar JG. Prion disease tempo determined by host-dependent substrate reduction. J Clin Invest. 2014 124(2):847-58. Lau A, McDonald A, Daude N, Mays CE, Walter E, Wohlgemuth S, Yang J, Shi B, van der Merwe J, Gapeshina H, Kim C, Grams J, Wille H, Balachandran A, Schmitt-Ulms G, Safar J, Millhauser G, Westaway D. “Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation”. EMBO Mol. Med. 2015 Feb 6; 7(3): 339-56. Mays CE, van der Merwe J, Kim C, Jaldiman T, McKenzie D, Safar JG, Westaway D. (2015) “Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species”. J Virol. Dec 15;89(24): 12418- 26.