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Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions. MGK Benesch, YM Ko, TPW McMullen and DN Brindley. FEBS Lett. 588 (2014) 2712-2727. Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine1-phosphate. MGK Benesch, YY Zhao, JM Curtis, TPW McMullen and DN Brindley J Lipid Res. J Lipid Res. in press, 2015, doi:10.1194/jlr.M057661. Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression. MGK Benesch, X Tang, J Dewald, W-F Dong, JR Mackey, DG Hemmings, TPW McMullen and DN Brindley. FASEB J, in press. Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. MGK Benesch, YM Ko, X Tang, J Dewald, A Lopez-Campistrous, YY Zhao, R Lai, JM Curtis, DN Brindley1 and TPW McMullen. Endocrine-Related Cancer, in press Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice. M Benesch, X Tang, T Maeda, A Ohata, Y Zhao, B Kok, J Dewald, M Hitt, J Curtis, T McMullen and DN Brindley, FASEB J. 28 (2014) 2655-2666. Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: Implications for cancer treatment. G Venkatraman, MGK Benesch, X Tang, J Dewald, TPW McMullen & DN Brindley. FASEB J. 29 (2015) 772-785. Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice. X Tang, MGK Benesch, J Dewald, YY Zhao, N Patwardhan, WL Santos, JM Curtis, TPW and DN Brindley. J Lipid Res. 55 (2014) 2389-2400