Narain, Ravin - University of Alberta - Department of Chemical and Materials Engineering

个人简介

Ravin NARAIN, PhD/PEng, is Professor in the Department of Chemical and Materials Engineering at the University of Alberta. He has published more than 120 articles in peer-reviewed journals and is the editor of three books namely Engineered Carbohydrate-Based Materials for Biomedical Applications (Wiley & Sons), Chemistry of Bioconjugates (Wiley & Sons) and Glycopolymers: Synthesis and Applications (Smithers & Rapra). He has also contributed more than 20 chapters in several books. Dr. Narain’s research examines nanomedicine and regenerative medicine, with an emphasis on developing new carbohydrate based biomaterials for drug and gene delivery for cancer therapy. In addition, he has an interest in interdisciplinary research and has extensive experience in developing innovative polymers, nanoparticles and nanofibers for advanced engineering applications.

研究领域

polymer chemistry, biomaterials and nanotechnology

近期论文

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Yohei Kotsuchibashi, Mitsuhiro Ebara, Takao Aoyagi,* and Ravin Narain,* Recent Advances in Dual Temperature Responsive Block Copolymers and Their Potential as Biomedical Applications, Polymers (2016), 8, 380. Yinan Wang, Lin Li, Yohei Kotsuchibashi, Sergey Vshyvenko, Yang Liu, Dennis Hall, Hongbo Zeng, Ravin Narain* Self-healing and injectable shear thinning hydrogels based on dynamic oxaborole-diol covalent crosslinking, ACS Biomaterials and Engineering (2016) in press Han Lu, Li Xiang, Xin Cui, Jing Liu, Yinan Wang, Ravin Narain, Hongbo Zeng, Molecular Weight Dependence of Synthetic Glycopolymers on Flocculation and Dewatering of Fine Particles, Langmuir (2016) in press Pallavi Bhambri, Brian Fleck, Ravin Narain, Thermo‐responsive polymers for drag reduction in turbulent Taylor–Couette flow, Journal of Applied Polymer Science, (2016), 133, 44191. Stephen Quan, Piyush Kumar, Ravin Narain* Cationic Galactose-Conjugated Copolymers for Epidermal Growth Factor (EGFR) Knockdown in Cervical Adenocarcinoma, ACS Biomaterials and Engineering (2016), 2, 853-859. Han Lu, Yinan Wang, Lin Li, Yohei Kotsuchibashi, Ravin Narain*, Hongbo Zeng* Temperature and pH Responsive Benzoboroxole based Polymers for Flocculation and Enhanced Dewatering of Fine Particle Suspensions, ACS Applied Materials & Interfaces (2015) in press Christian Adokoh, James Darkwa, Ravin Narain Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications, Macro-Glycoligands: Methods and Protocols, (2015) 109-121 Christian Adokoh, James Darkwa, Ravin Narain Synthetic Approach to Glycopolymer Base Nanoparticle Gold (I) Conjugate: A New Generation of Therapeutic Agents, Macro-Glycoligands: Methods and Protocols, (2015) 157-168 Marya Ahmed, Ravin Narain* “Carbohydrate Based Materials for Targeted Delivery of Drugs and Genes to the liver”, Nanomedicine, (2015) 10, 2263-2288 (Invited Review) Stephen Quan, Yinan Wang, Aihua Zhou, Piyush Kumar, Ravin Narain* Galactose-based Thermosensitive Nanogels for Targeted Drug Delivery of Iodoazomycin Arabinofuranoside (IAZA) for Theranostic Management of Hypoxic Hepatocellular Carcinoma, Biomacromolecules, (2015), 16, 1978–1986. Yinan Wang, Yohei Kotsuchibashi, Yang Liu* and Ravin Narain* Study of Bacterial Adhesion on Biomimetic Temperature Responsive Glycopolymer Surfaces, ACS Applied Materials and Interfaces, (2015), 7, 1652-1661. Bindu Thapa, Piyush Kumar, Hongbo Zeng and Ravin Narain* Asialoglycoprotein Receptor-Mediated Gene Delivery to Hepatocytes Using Galactosylated Polymers, Biomacromolecules, (2015), 16, 3008–3020. Ravin Narain*, Yinan Wang, Marya Ahmed, Benjamin Lai, Jayachandran Kizhakkedathu Blood Components interactions of Ionic and Non-Ionic Glyconanogels, Biomacromolecules (2015), 16, 2990–2997. Christian K. Adokoh, Stephen Quan, Mary Hitt, James Darkwa, Piyush Kumar, Ravin Narain* “Synthesis and Evaluation of Polymeric Galactose-Decorated Gold Nanoparticles Functionalized with Gold-Triphenyl Phosphine as Anti-Cancer Agents” Biomacromolecules (2014) 15 (10), 3802-3810 Yinan Wang, Yohei Kotsuchibashi, Koichiro Uto, Mitsuhiro Ebara, Takao Aoyagi, Yang Liu, Ravin Narain* “pH and glucose responsive nanofibers for the reversible capture and release of lectins” Biomaterials Science (2015) DOI: 10.1039/C4BM00269E Yohei Kotsuchibashi, Mitsuhiro Ebara, Takeshi Sato, Yinan Wang, Rajender Rajender, Dennis G. Hall, Ravin Narain*, and Takao Aoyagi*, “Spatio-Temporal Control of Synergistic Gel Formation Consisting of Boroxole- and Glyco-Based Polymers via Photoinduced Proton Transfer” to be submitted to Journal of Physical Chemistry B (2014) (Invited) DOI: 10.1021/jp506478p Yohei Kotsuchibashi, Mitsuhiro Ebara, Ravin Narain, and Takao Aoyagi, “Temperature-responsive mixed core nanoparticle properties determined by the composition of statistical and block copolymers in the core” Polymer Chemistry (2015) 6 1693-1697. Yinan Wang, Ravin Narain* and Yang Liu* “Study of bacterial adhesion on glycopolymers-treated gold surfaces using quartz crystal microbalance with dissipation (QCM-D)” Langmuir, (2014), 30 (25), pp 7377–7387 Rajesh Sunasee, Christian Adokoh, James Darkwa, Ravin Narain* “Therapeutic Potentials of Glycopolymers and Glyconanoparticles” Expert Opinion on Drug Delivery (2014) 11 (6), 867-884 Yinan Wang, Yohei Kotsuchibashi, Yang Liu*, Ravin Narain* “Temperature Responsive Hyperbranched Amine-Based Polymers for Solid-Liquid Separation” Langmuir, (2014), 30 (9), 2360-2368 Marya Ahmed, Kazuhiko Ishihara, Ravin Narain* “Calcium mediated formation of phosphorylcholine-based polyplexes for efficient knockdown of epidermal growth factor receptors (EGFR) in HeLa cells” Chem. Commun. (2014) 50, 2943-2946 Yohei Kotsuchibashi, Ravin Narain* “Dual-Temperature and pH Responsive (Ethylene Glycol)-Based Nanogels via Structural Design” Polymer Chemistry, (2014) 5 (8), 3061-3070 Pavel Kitov, Yohei Kotsuchibashi, Eugenia Paszkiewicz, Dennis Wilhelm, Ravin Narain, David Bundle “Poly(N‑vinyl-2-pyrrolidone-co-vinyl alcohol), a Versatile Amphiphilic Polymeric Scaffold for Multivalent Probe” Organic Letters (2013), 15, 5190–5193 Marya Ahmed, Phanphen Wattanaarsakit, Ravin Narain* “Cationic Glyco-Nanogels for Epidermal Growth Factor Receptor (EGFR) specific siRNA delivery in Cancer Cells” Polymer Chemistry, (2013), 4 (13), 3829-3836 Marya Ahmed, Saul Mamba, Xiao-Hong Yang, James Dwarka, Piyush Kumar, Ravin Narain* “Synthesis and Evaluation of Polymeric Gold Glyco-Conjugates as Anti-Cancer Agents” Bioconjugate Chemistry (2013) 24 (6), 979-986.