Low, Wan - University of Wolverhampton - Faculty of Science & Engineering

个人简介

Dr. Wan Li Low (BSc. (Hons), PhD, CBiol, MRSB, MAPS), is an experienced scientist, capable of delivering high quality teaching and research with a wide range of knowledge and expertise spanning the interdisciplinary fields of pharmaceutical sciences, formulation aspects of antimicrobial drug delivery, microbiology, biotechnology and biology. Upon completing her PhD in liposomal delivery of antimicrobial metal ions and essential oils, she was appointed as a Process Development Scientist as part of a Knowledge Transfer Partnership (KTP) programme between OSIL Ltd. and the University of Wolverhampton. Dr. Low demonstrated excellent qualities to bridge scientific knowledge and research with appropriate business acumen, which resulted in successful project outcomes combined with a prestigious award as the “Business Leader of Tomorrow 2013”. The project was a great success and the Technology Strategy Board awarded additional funding to extend the project, as well as an “Excellent” project grade for its outstanding impact on both the business and the university. Dr. Low continued her research career as a post-doctoral fellow with the Anti-Infective Delivery Research Group (AIDRG) within the School of Pharmacy at the University of Wolverhampton. Her research within AIDRG focuses on the development of smart, responsive controlled release delivery systems to deliver alternative non-antibiotic antimicrobial agents for the management of chronic wound infections. Dr. Low’s contribution to research in biological sciences has been recognised by the Royal Society of Biology with the award of Chartered Biologist (CBiol) status. As Lecturer in Pharmacy Science, Dr. Low is currently contributing to teaching and research activities on the MPharm, BSc. (Hons) Pharmaceutical Science and MSc. degree courses within the School of Pharmacy.

研究领域

Antimicrobial activity of essential oils (e.g. tea tree oil) and metal ions (e.g. silver) Development of preparations combining tea tree oil with silver for application in wound healing Controlled delivery of antimicrobial agents using a variety of drug delivery systems e.g. liposome encapsulation and hydrogel formulations Creation of a wound management devices that enhance wound healing, reduces the frequency of dressing changes and minimizes impact of antimicrobial agents on healthy tissue and the environment In vitromodelling of the wound healing process Formulation of responsive, controlled release delivery systems for wound management Formulation and assay development of novel antimicrobial agents

近期论文

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Low, W.L., Kenward, M.A., Britland, S.T., Amin, M.C.I.M. and Martin, C. (2016). Essential oils and metal ions as alternative antimicrobial agents: a focus on tea tree oil and silver. International Wound Journal. DOI: 10.1111/iwj.12611. Low, W.L., Kenward, M.A. and Martin, C. (2016). Ionically crosslinked chitosan hydrogels for the controlled release delivery of antimicrobial essential oils and metal ions. Medicines, 3(1): 8; DOI:10.3390/medicines3010008. Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2016) Characterisation and in vitro Antimicrobial Potential of Liposomal Silver Ions against Candida albicans. Journal of Microencapsulation, 33(2): 146-152. Gupta, A., Britland, S.T., Radecka, I., Low, W.L. and Martin, C. (2016). Development of biosynthetic cellulose hydrogels loaded with antimicrobial silver nanoparticles for wound dressing applications. UKPharmSci 2016 Conference Proceedings, 5th – 7thSeptember 2016, Technology & Innovation Centre, University of Strathclyde, Glasgow, U.K. Martin, C., Low, W.L., Gupta, A., Amin, M.C.I.M., Radecka, I., Britland, S.T., Raj, P. and Kenward, M.A. (2015). Strategies for Antimicrobial Drug Delivery to the Biofilm. Current Pharmaceutical Design, 21 (1): 43-66. Dosanjh, P.K., Low, W.L., Radecka, I., Britland, S.T. and Martin, C. (2015). Liposomal silver nitrate embedded within a bacterial cellulose hydrogel: Antimicrobial activity against Pseudomonas aeruginosa and Staphylococcus aureus. Liposome Advances 2015 Conference Proceedings, 19th – 22nd December 2015, UCL School of Pharmacy, University of London, London, U.K.