Thomas, Gavin H - York University - Department of Biology

个人简介

2016 - Reader Department of Biology, University of York 2010 - 2016 Senior Lecturer Department of Biology, University of York 2002 - 2010 Lecturer Department of Biology, University of York 2000 - 2002 Postdoctoral Research Fellow Department of Molecular Biology and Biotechnology, University of Sheffield 1998 - 2000 Postdoctoral Research Fellow Molecular Microbiology department at the John Innes Centre, Norwich 1995 - 1998 PhD in Biochemistry Birmingham University 1992 - 1995 BSc (Hons) Bristol University

研究领域

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The Thomas group has two main interests that are linked by the bacterium Escherichia coli. We are interested in the mechanisms used by different bacteria, mainly human pathogens, to utilise the important host-derived molecule sialic acid. This includes how this sugar acid is transported across the inner membrane of bacteria and here we study the sialic acid-specific tripartite ATP-independent periplasmic (TRAP) transporter from Haemophilus influenzae as our main system. We also used constraint-based modelling to understand the obligate symbiosis between a number of bacteria and their insect hosts, focussing mainly on the interaction between the E. coli relative Buchnera aphidicola and its aphid host.