Jones, Louise - York University - Department of Biology

个人简介

2002 - Lecturer Department of Biology, University of York 1998 - 2002 Research Scientist Sainsbury Laboratory, John Innes Centre, Norwich 1995 - 1998 Post-doc Department of Virus Research, John Innes Centre, Norwich 1992 - 1995 Post-doc Department of Plant Pathology, University of California, Davis, USA 1988 - 1991 PhD Department of Genetics, University of Leicester 1985 - 1988 BSc (hons) Biological Science, University of Leicester

研究领域

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I have a long-standing interest in RNA biology and post-transcriptional control of gene expression. A particular focus is RNA silencing, which is a conserved mechanism of gene regulation in eukaryotes and is involved in controlling endogenous gene expression and defence against invasive nucleic acids such as viruses. Interestingly RNA silencing can promote epigenetic changes such as DNA methylation and histone modification and one idea is that these pathways contribute to phenotypic plasticity in response to environmental change. Currently my lab is using a combination of molecular and genetic approaches to investigating the connection between RNA silencing and DNA methylation and its wider significance.