个人简介
Ian Hitchcock is a Lecturer in Biomedical Sciences based in the Centre for Immunology and Infection. He was awarded his BSc and PhD in Biology from the Department of Biology at the University of York, before becoming a postdoctoral fellow in the laboratory of Professor Kenneth Kaushansky in the Department of Medicine at the University of California San Diego. In 2007 he was made an Assistant Professor at the University of California San Diego and moved to the Department of Medicine at Stony Brook University, New York in 2010. He has been at the University of York since July 2014.
研究领域
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Myeloproliferative neoplasms
Regulation of haematopoietic cytokine signalling
Platelet signalling and function
Thrombosis and haemostasis
Blood cell production (haematopoiesis) is tightly regulated by a number of different factors to ensure that the numbers of circulating blood cells are maintained within a physiological range. Haematopoietic cytokines and their receptors are essential in regulating blood cell production, and consequently, aberrant haematopoietic cytokine singling can often lead to haematological malignancies or myelodysplatic syndromes. Our lab is interested in the molecular mechanisms of haematopoietic cytokine signalling and how mutations in cytokine receptors and their associated proteins cause haematological disorders and vascular complications in humans.