Chawla , Sangeeta - University of York

个人简介

Career 2010 - Lecturer Department of Biology, University of York 2003 - 2009 BBSRC David Phillips Fellow University of Cambridge 2000 - 2003 Post-Doc University of Cambridge 1997 - 2000 Post-Doc MRC Laboratory of Molecular Biology 1997 PhD MRC Laboratory of Molecular Biology 1993 MPhil University of Cambridge 1992 MSc Jawaharlal Nehru University, India 1990 BSc (Hons) University of Delhi, India

研究领域

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Research in the laboratory is aimed at understanding how neuronal transcription factors respond to growth factors and synaptic activity to direct gene expression programs underlying neuronal differentiation, neuronal growth and synaptic plasticity. We are specifically interested in the regulation of CREB, serum response factor, Elk-1, Class IIa HDACs and the myocyte enhancer factor-2 family of proteins in rodent hippocampal neurons and in differentiating neural progenitors. We are using Drosophila to investigate the role of these transcriptional regulators in learning and memory and in generating rhythmic behaviours such as circadian rhythms of locomotor activity. One aim of our work is to investigate changes in transcription factor regulation in neurodegenerative diseases that are associated with transcriptional dysfunction.