Brackenbury, Will - York University - Department of Biology

个人简介

2016 - Lecturer in Biomedical Sciences Department of Biology, University of York 2011 - 2016 MRC Career Development Fellow Department of Biology, University of York 2009 - 2010 Adjunct Lecturer University of Michigan 2006-2010 Post-doc University of Michigan Medical School 2006 PhD Biological Sciences Imperial College London 2002 BSc Biology Imperial College London

研究领域

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Voltage-gated sodium channels are responsible for the initiation and propagation of action potentials, and are therapeutic targets in excitability-related disorders including cardiac arrhythmias, pain and epilepsy. They also play an important role in regulating neuronal pathfinding and migration during brain development. I am interested in the novel role of sodium channels in regulating the migration and invasion of metastatic cancer cells. This requires understanding the mechanisms by which sodium channels regulate adhesion and migration, during nervous system development on the one hand, and cancer metastasis on the other. An important focus of research in my lab is to extend in vitro observations from cell lines towards the clinic, developing in vivo models and human tissue sample analyses.